scholarly journals Impaired spatial working memory in children with well-controlled epilepsy: An event-related potentials study

Seizure ◽  
2011 ◽  
Vol 20 (2) ◽  
pp. 143-150 ◽  
Author(s):  
I. Myatchin ◽  
L. Lagae
Keyword(s):  
Working Memory ◽  
Spatial Working Memory ◽  
Event Related Potentials ◽  
Related Potentials

Abnormal auditory N400 in a case of zolpidem dependence, during a working memory test

2006 ◽  
Vol 21 (2) ◽  
pp. 135-137 ◽  
Author(s):  
Ioannis A. Liappas ◽  
Charalabos C. Papageorgiou ◽  
Andreas D. Rabavilas
Keyword(s):  
Working Memory ◽  
Spatial Working Memory ◽  
Event Related Potentials ◽  
Short Term ◽  
Context Processing ◽  
Gaba A ◽  
Related Potentials ◽  
N400 Component ◽  
Underlying Mechanisms ◽  
Term Management

AbstractZolpidem is a GABA (A) agonist, which is indicated for the short-term management of insomnia. Recent research provide evidence suggesting that zolpidem produces spatial working memory (WM) deficits and dependence; however, the underlying mechanisms of these effects are unknown. Since the auditory N400 component of event-related potentials (ERPS) is considered as an index of memory use of context processing, the present study focused on N400 waveform of ERPs elicited during a WM task in a case suffering from zolpidem dependence. The patterns of N400 waveform of this case were compared to the patterns obtained from healthy controls. This comparison revealed that zolpidem dependence is accompanied by reduced amplitudes located at posterior brain areas and diffuse prolongation of N400. These findings may indicate that zolpidem dependence manifests alterations with regard to the memory use of context processing, involving or affecting a wide-ranging network of the brain's structures.

Event-Related Potentials in Young and Elderly Adults during a Visual Spatial Working Memory Task

2004 ◽  
Vol 35 (4) ◽  
pp. 185-192 ◽  
Author(s):  
Verner Knott ◽  
Anne Millar ◽  
Louise Dulude ◽  
Lisa Bradford ◽  
Fahad Alwahhabi ◽  
...  
Keyword(s):  
Working Memory ◽  
Spatial Working Memory ◽  
Memory Task ◽  
Event Related Potentials ◽  
Elderly Adults ◽  
Visual Spatial ◽  
Related Potentials ◽  
Visual Spatial Working Memory

The Role of Spatial Selective Attention in Working Memory for Locations: Evidence from Event-Related Potentials

2000 ◽  
Vol 12 (5) ◽  
pp. 840-847 ◽  
Author(s):  
Edward Awh ◽  
Lourdes Anllo-Vento ◽  
Steven A. Hillyard
Keyword(s):  
Working Memory ◽  
Selective Attention ◽  
Visual Processing ◽  
Spatial Working Memory ◽  
Memory Task ◽  
Stimulus Display ◽  
Event Related Potentials ◽  
Related Potentials ◽  
On Line ◽  
Multichannel Recordings

We investigated the hypothesis that the covert focusing of spatial attention mediates the on-line maintenance of location information in spatial working memory. During the delay period of a spatial working-memory task, behaviorally irrelevant probe stimuli were flashed at both memorized and nonmemorized locations. Multichannel recordings of event-related potentials (ERPs) were used to assess visual processing of the probes at the different locations. Consistent with the hypothesis of attention-based rehearsal, early ERP components were enlarged in response to probes that appeared at memorized locations. These visual modulations were similar in latency and topography to those observed after explicit manipulations of spatial selective attention in a parallel experimental condition that employed an identical stimulus display.

Auditory event-related potentials during a spatial working memory task

2008 ◽  
Vol 119 (5) ◽  
pp. 1176-1189 ◽  
Author(s):  
S.K. Rader ◽  
J.L. Holmes ◽  
E.J. Golob
Keyword(s):  
Working Memory ◽  
Spatial Working Memory ◽  
Memory Task ◽  
Event Related Potentials ◽  
Auditory Event ◽  
Related Potentials ◽  
Auditory Event Related Potentials

scholarly journals Hydrolyzed Chicken Extract (ProBeptigen®) on Cognitive Function in Healthy Middle-Aged People: A Randomized Double-Blind Trial

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1362
Author(s):  
Dean Wu ◽  
Cheng-Chang Yang ◽  
Kuan-Yu Chen ◽  
Ying-Chin Lin ◽  
Pei-Jung Wu ◽  
...  
Keyword(s):  
Working Memory ◽  
Placebo Group ◽  
Cognitive Aging ◽  
Spatial Working Memory ◽  
Memory Task ◽  
Event Related Potentials ◽  
Mild Stress ◽  
Middle Aged ◽  
Aged People ◽  
Related Potentials

Cognitive decline is an important issue of global public health. Cognitive aging might begin at middle adulthood, the period particularly vulnerable to stress in lifespan. Essence of chicken (EOC) has consistently demonstrated its beneficial effects on various cognitive domains as nutritional supplementation. This study primarily aimed to examine the cognitive enhancement effects of ProBeptigen® (previously named CMI-168), hydrolyzed peptides extracted from EOC, in healthy middle-aged people under mild stress. Ninety healthy subjects were randomly assigned into the ProBeptigen® or placebo group for eight weeks. Neurocognitive assessment, event-related potentials (ERPs), and blood tests were conducted before, during, and after the treatment. The ProBeptigen® group outperformed placebo group on Logical Memory subtests of Wechsler Memory Scale-third edition (WMS-III) and Spatial Working Memory task in the Cambridge Neuropsychological Test Automated Battery (CANTAB). The anti-inflammatory effects of ProBeptigen® in humans were also confirmed, with progressively declining high-sensitivity C-reactive protein (hs-CRP) levels. Regular dietary supplementation of ProBeptigen® is suggested to improve verbal short- and long-term memory as well as spatial working memory, and reduce inflammation in middle-aged healthy individuals with stress. The effects of ProBeptigen® on cognition warrant further investigation. (NCT03612752)

Event-related potentials and spatial working memory evidence from auditory and visual modalities

1997 ◽  
Vol 25 (1) ◽  
pp. 26
Author(s):  
M. Martin-Loeches ◽  
F. Barcelo ◽  
F.J. Rubia
Keyword(s):  
Working Memory ◽  
Spatial Working Memory ◽  
Event Related Potentials ◽  
Related Potentials

Human Event-Related Potentials to Higher-Order Acoustic Spatial Changes

2002 ◽  
Vol 16 (2) ◽  
pp. 114-118 ◽  
Author(s):  
Timo Ruusuvirta ◽  
Heikki Hämäläinen
Keyword(s):  
Working Memory ◽  
Mismatch Negativity ◽  
Spatial Information ◽  
Free Field ◽  
Event Related Potentials ◽  
Negative Polarity ◽  
Positive Polarity ◽  
Spatial Changes ◽  
Related Potentials ◽  
Human Event

Abstract Human event-related potentials (ERPs) to a tone continuously alternating between its two spatial loci of origin (middle-standards, left-standards), to repetitions of left-standards (oddball-deviants), and to the tones originally representing these repetitions presented alone (alone-deviants) were recorded in free-field conditions. During the recordings (Fz, Cz, Pz, M1, and M2 referenced to nose), the subjects watched a silent movie. Oddball-deviants elicited a spatially diffuse two-peaked deflection of positive polarity. It differed from a deflection elicited by left-standards and commenced earlier than a prominent deflection of negative polarity (N1) elicited by alone-deviants. The results are discussed in the context of the mismatch negativity (MMN) and previous findings of dissociation between spatial and non-spatial information in auditory working memory.

scholarly journals Temporal Dynamics of Attention during Encoding versus Maintenance of Working Memory: Complementary Views from Event-related Potentials and Alpha-band Oscillations

2015 ◽  
Vol 27 (3) ◽  
pp. 492-508 ◽  
Author(s):  
Nicholas E. Myers ◽  
Lena Walther ◽  
George Wallis ◽  
Mark G. Stokes ◽  
Anna C. Nobre
Keyword(s):  
Working Memory ◽  
Visual Information ◽  
Temporal Dynamics ◽  
Recall Performance ◽  
Event Related Potentials ◽  
Alpha Band ◽  
Related Potentials ◽  
Frontoparietal Control Network ◽  
Anticipatory Attention ◽  
Processing Differences

Working memory (WM) is strongly influenced by attention. In visual WM tasks, recall performance can be improved by an attention-guiding cue presented before encoding (precue) or during maintenance (retrocue). Although precues and retrocues recruit a similar frontoparietal control network, the two are likely to exhibit some processing differences, because precues invite anticipation of upcoming information whereas retrocues may guide prioritization, protection, and selection of information already in mind. Here we explored the behavioral and electrophysiological differences between precueing and retrocueing in a new visual WM task designed to permit a direct comparison between cueing conditions. We found marked differences in ERP profiles between the precue and retrocue conditions. In line with precues primarily generating an anticipatory shift of attention toward the location of an upcoming item, we found a robust lateralization in late cue-evoked potentials associated with target anticipation. Retrocues elicited a different pattern of ERPs that was compatible with an early selection mechanism, but not with stimulus anticipation. In contrast to the distinct ERP patterns, alpha-band (8–14 Hz) lateralization was indistinguishable between cue types (reflecting, in both conditions, the location of the cued item). We speculate that, whereas alpha-band lateralization after a precue is likely to enable anticipatory attention, lateralization after a retrocue may instead enable the controlled spatiotopic access to recently encoded visual information.

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