Emerging Treatments for Insomnia, Sleep Apnea, and Restless Leg Syndrome Among Dialysis Patients

2021 ◽  
Vol 41 (6) ◽  
pp. 526-533
Author(s):  
Shanna Diaz ◽  
Kashif Abad ◽  
Sanjay R. Patel ◽  
Mark L. Unruh
Keyword(s):  
Sleep Apnea ◽  
Restless Leg Syndrome ◽  
Dialysis Patients ◽  
Emerging Treatments

scholarly journals Risk, Severity, and Predictors of Obstructive Sleep Apnea in Hemodialysis and Peritoneal Dialysis Patients

2018 ◽  
Vol 15 (11) ◽  
pp. 2377 ◽  
Author(s):  
Shih-Ting Huang ◽  
Chen-Li Lin ◽  
Tung-Min Yu ◽  
Chia-Hung Kao ◽  
Wen-Miin Liang ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Peritoneal Dialysis ◽  
Sleep Apnea ◽  
Cox Regression ◽  
Study Cohort ◽  
Research Database ◽  
Control Cohort ◽  
Dialysis Patients ◽  
Cpap Treatment ◽  
Obstructive Sleep

Our study aimed to determine the incidence and severity of obstructive sleep apnea (OSA) in patients with end-stage renal disease (ESRD) and also whether different dialysis modalities confer different risk and treatment response for OSA. We used Taiwan’s National Health Insurance Research Database for analysis and identified 29,561 incident dialysis patients as the study cohort between 2000 and 2011. Each dialysis patient was matched with four non-dialysis control cases by age, sex, and index date. Cox regression hazard models were used to identify the risk of OSA. The incidence rate of OSA was higher in the peritoneal dialysis (PD) cohort than the hemodialysis (HD) and control cohort (18.9, 7.03 vs. 5.5 per 10,000 person-years, respectively). The risk of OSA was significantly higher in the PD (crude subhazard ratio (cSHR) 3.50 [95% CI 2.71–4.50], p < 0.001) and HD cohort (cSHR 1.31 [95% CI 1.00–1.72], p < 0.05) compared with the control cohort. Independent risk factors for OSA in this population were age, sex, having coronary artery disease (CAD), hyperlipidemia, chronic obstructive pulmonary disease (COPD), and hypertension. Major OSA (MOSA) occurred in 68.6% in PD and 50.0% in HD patients with OSA. In the PD subgroup, the incidence of mortality was significantly higher in OSA patients without continuous positive airway pressure (CPAP) treatment compared with OSA patients undergoing CPAP treatment. The results of this study indicate that ESRD patients were at higher risk for OSA, especially PD patients, compared with control. The severity of OSA was higher in PD patients than HD patients. Treatment of MOSA with CPAP was associated with reduced mortality in PD patients.

Effects of nocturnal oxygen therapy on sleep apnea syndrome in peritoneal dialysis patients

2008 ◽  
Vol 70 (10) ◽  
pp. 332-339 ◽  
Author(s):  
T. Kumagai ◽  
Y. Ishibashi ◽  
H. Kawarazaki ◽  
W. Kawarazaki ◽  
H. Shimizu ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Sleep Apnea ◽  
Oxygen Therapy ◽  
Sleep Apnea Syndrome ◽  
Dialysis Patients ◽  
Apnea Syndrome ◽  
Nocturnal Oxygen Therapy

“I Am Pregnant; Why Can’t I Sleep?”

2017 ◽  
Author(s):  
Sandra L. Horowitz
Keyword(s):  
Sleep Apnea ◽  
Gestational Hypertension ◽  
Adverse Outcomes ◽  
Airflow Limitation ◽  
Poor Sleep ◽  
Hormonal Changes ◽  
Restless Leg Syndrome ◽  
Pregnancy And Postpartum ◽  
Induced Hypertension ◽  
The Common

This chapter reviews the common sleep disorders of pregnancy. During pregnancy and postpartum, 84% of women report poor sleep at least a few nights a week. These problems are common, disruptive to daytime and nighttime activity, and may have multiple causes. This chapter covers aspects of insomnia and restless leg syndrome. It also discusses sleep apnea in pregnancy with related hormonal changes that may increase the incidence. There is an association of sleep apnea and pregnancy-induced hypertension, with increased adverse outcomes of pregnancy, including fetal growth retardation and premature birth. It has been suggested that treating nocturnal airflow limitation may improve gestational hypertension. The recommended therapies in this chapter may also be applied to non-pregnant patients with similar complaints.

Sleep Disorders in Peritoneal and Haemodialysis Patients as Assessed by a Self-Administered Questionnaire

2000 ◽  
Vol 23 (4) ◽  
pp. 237-242 ◽  
Author(s):  
A. De Vecchi ◽  
S. Finazzi ◽  
R. Padalino ◽  
T. Santagostino ◽  
E. Bottaro ◽  
...  
Keyword(s):  
Sleep Disorders ◽  
Early Morning ◽  
Restless Leg Syndrome ◽  
Dialysis Patients ◽  
Dialysis Dose ◽  
Sleeping Pills ◽  
The Relationship ◽  
Self Administered Questionnaire ◽  
Frequent Problem

Sleep disorders have been reported as a frequent problem in dialysis patients. However, only one paper has compared the prevalence and possible causes of this complication in peritoneal (PD) and haemodialysis (HD) patients. We surveyed 84 PD and 87 HD patients about disordered sleep using a self-administered questionnaire. Forty-nine percent of PD and 56% of HD patients reported problems sleeping. These problems were rated as severe by 29 PD and 22 HD patients. Type of disturbances involved delayed sleeping (13 PD and 32 HD, p< 0.005), interrupted sleep (32 PD and 44 HD) and early morning awakening (25 PD and 37 HD). The number of hours of sleep varied widely among patients: it was 5 and 21 minutes in PD patients with sleep disorders and 7 and 37 min in PD pts without such problems. No statistically significant relationship was evidenced between sleep disorders and age, sex, body weight, obesity, duration of dialysis, dialysis dose, self-assessed sadness, anxiety, worry, pain, pruritus, dyspnoea, restless leg syndrome, use of cigarettes, caffeine, or sleeping pills. In conclusion, sleep disorders are a frequent problem in both PD and HD patients. Apparently the relationship with demographics, dialysis dose, lifestyle and personality traits is poor. The possible role of other causes should be investigated.

scholarly journals Relationship among end-stage renal disease, hypertension, and sleep apnea in nondiabetic dialysis patients

2005 ◽  
Vol 18 (2) ◽  
pp. 152-157 ◽  
Author(s):  
C DEOLIVEIRARODRIGUES ◽  
O MARSON ◽  
S TUFIC ◽  
O KOHLMANNJR ◽  
S GUIMARAES ◽  
...  
Keyword(s):  
Sleep Apnea ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Dialysis Patients ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Common sleep disorders in women

2021 ◽  
pp. 24-30
Author(s):  
Elsa Mathew ◽  
◽  
Antony Fernandez ◽  
Leslee E Hudgins ◽  
Shekar Raman ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Disorders ◽  
Sleep Disturbances ◽  
Adult Life ◽  
Reproductive Hormones ◽  
Restless Leg Syndrome ◽  
Adult Life Span ◽  
Pressure Therapy ◽  
Obstructive Sleep

Sleep disturbances contribute to a high frequency of mental health and cardiovascular diseases with significant gender differences. Women have a higher incidence than men of insomnia and are more likely than men to complain of insomnia, headache, irritability, and fatigue than the ‘‘typical’’ symptoms of loud snoring and apneas during sleep. Reproductive hormones play an important role in sleep in women. In the premenopausal age these hormones have a protective effect on sleep apnea while on pregnancy there is a higher prevalence of sleep apnea and restless legs syndrome. Cardiovascular mortality is high in women with obstructive sleep apnea and continuous positive airway pressure therapy improves outcomes in most cases of obstructive sleep apnea. The epidemiology, risk factors, diagnostic criteria, and therapies for the three most common sleep disorders (insomnia, obstructive sleep apnea, and restless leg syndrome), along with effects of menopause, pregnancy, and social factors on sleep in women, are key considerations for clinicians caring for female patients across the adult life span.

scholarly journals Dialysis Patients With Restless Leg Syndrome: Can We Relieve Their Suffering?

Cureus ◽  
2020 ◽  
Author(s):  
Marina Salib ◽  
Areeba N Memon ◽  
Asavari S Gowda ◽  
Bhavana Rallabhandi ◽  
Erjola Bidika ◽  
...  
Keyword(s):  
Restless Leg Syndrome ◽  
Dialysis Patients
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