A green synthesis of MOR zeolite membranes by wet gel conversion for dehydration of water-acetic acid mixtures

compound 2-((1H-benzo[d]imidazol-2-yl)thio)acetic acid (1) with o-aminobenzamide (2) gave compound (2-[1-(1H-benzimidazol-2-yl)-ethylsulfanyl]-3H-quinazolin-4-one (3). 3 could also be syntehsized by an alternative two routes scheme 2 and scheme 3. It appears from scheme 3 that it is giving good yields under green and eco-friendly conditions using PEG-600 (polyethylent glycol). Compound 10 was synthesized in two routes scheme4 and scheme 5. It appears from Route B (Scheme 4) that it is giving good yields: alkylation followed by oxidation in route A followed by alkylation in PEG-600 used as a green solvent. The total sequence of reactions has been carried out using eco-friendly and green conditions. Further, anticancer activity was carried out by using docking studies and binding conformation of active compounds of 3, 8, 9 and 10. The results show that 3 and 9 have potential to be developed as chemotherapeutic agents and compounds 3, 9 molecule showed best fit, potent dock score when compared with doxorubicin.

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Efficient and green synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones using imidazol-1-yl-acetic acid as a novel, reusable and water-soluble organocatalyst

Catalysis Communications ◽

10.1016/j.catcom.2011.08.022 ◽

2011 ◽

Vol 15 (1) ◽

pp. 123-126 ◽

Cited By ~ 24

Author(s):

Mojgan Kargar ◽

Rahim Hekmatshoar ◽

AbdolJalil Mostashari ◽

Zahra Hashemi

Keyword(s):

Acetic Acid ◽

Green Synthesis ◽

Water Soluble

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AN ULTRASOUND MEDIATED GREEN SYNTHESIS OF 2-PYRAZOLINE DERIVATIVES

10.36106/ijsr/9527056 ◽

2021 ◽

pp. 36-39

Author(s):

Shrivastava Birendra ◽

Upasna Upasna ◽

Arora Satish Chander

Keyword(s):

Acetic Acid ◽

Green Synthesis ◽

19Th Century ◽

Heterocyclic Compounds ◽

Unsaturated Aldehydes ◽

Aldehydes And Ketones ◽

The 19Th Century

Pyrazolines are prominent nitrogen-containing heterocyclic compounds and therefore, various procedures have been worked out for their synthesis. After the pioneering work of Fischer and Knoevenagel in the 19th century, the reaction of α, β-unsaturated aldehydes and ketones with phenylhydrazine in acetic acid by reuxing became one of the most popular methods for the preparation of 2-pyrazolines. Aseries of substituted 2- pyrazolines was synthesized by ultrasound irradiated method to nd out cleaner/ greener approaches.

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Dehydration of Concentrated Acetic Acid Solutions by Pervaporation Using Novel MER Zeolite Membranes

Chemistry Letters ◽

10.1246/cl.2007.594 ◽

2007 ◽

Vol 36 (5) ◽

pp. 594-595 ◽

Cited By ~ 19

Author(s):

Takako Nagase ◽

Yoshimichi Kiyozumi ◽

Yasuhisa Hasegawa ◽

Tomoya Inoue ◽

Takuji Ikeda ◽

...

Keyword(s):

Acetic Acid ◽

Acid Solutions ◽

Zeolite Membranes

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ChemInform Abstract: Green Synthesis of 2-Amino-5-substituted-1,3,4-oxadiazoles at the Platinum Anode in Acetic Acid.

ChemInform ◽

10.1002/chin.201116132 ◽

2011 ◽

Vol 42 (16) ◽

pp. no-no

Author(s):

Laxmi Kant Sharma ◽

Sushma Singh ◽

R. K. P. Singh

Keyword(s):

Acetic Acid ◽

Green Synthesis ◽

Platinum Anode

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Acetic Acid Dehydration by Pervaporation Zeolite Membranes

Encyclopedia of Membranes ◽

10.1007/978-3-642-40872-4_956-1 ◽

2014 ◽

pp. 1-1

Author(s):

Reyes Mallada

Keyword(s):

Acetic Acid ◽

Zeolite Membranes

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Acetic acid-promoted condensation of o-phenylenediamine with aldehydes into 2-aryl-1-(arylmethyl)-1H-benzimidazoles under microwave irradiation

Journal of the Serbian Chemical Society ◽

10.2298/jsc090901096a ◽

2010 ◽

Vol 75 (9) ◽

pp. 1181-1189 ◽

Cited By ~ 28

Author(s):

Davood Azarifar ◽

Mojgan Pirhayati ◽

Behrooz Maleki ◽

Mehrangiz Sanginabadi ◽

Nejat Yami

Keyword(s):

Acetic Acid ◽

Transition Metal ◽

Microwave Irradiation ◽

Green Synthesis ◽

Simple Procedure ◽

High Yields

An efficient and simple procedure was developed for the green synthesis of various 2-aryl-1-(arylmethyl)-1H-benzimidazoles in high yields by acetic acid-promoted condensation of o-phenylenediamine with aldehydes in air under microwave irradiation and transition metal catalystfree conditions.

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