A structural brain network analysis for rapid eye movement sleep behavior disorder (RBD) patients

2017 ◽  
Vol 40 ◽  
pp. e183
Author(s):  
E.J. Lee ◽  
J.E. Yoon ◽  
M.-H. Lee ◽  
A. Min ◽  
Y.H. Hwang ◽  
...  
Keyword(s):  
Network Analysis ◽  
Eye Movement ◽  
Behavior Disorder ◽  
Brain Network ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Sleep Behavior ◽  
Structural Brain Network ◽  
Structural Brain

Convergent patterns of structural brain changes in rapid eye movement sleep behavior disorder and Parkinson’s disease on behalf of the German rapid eye movement sleep behavior disorder study group

SLEEP ◽  
2020 ◽  
Author(s):  
Florian Holtbernd ◽  
Sandro Romanzetti ◽  
Wolfgang Hermann Oertel ◽  
Susanne Knake ◽  
Elisabeth Sittig ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Eye Movement ◽  
Diffusion Tensor ◽  
Behavior Disorder ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Sleep Behavior ◽  
Brain Changes ◽  
Structural Brain

Abstract Study Objectives Rapid eye movement sleep behavior disorder (RBD) is considered a prodromal state of Parkinson’s disease (PD). We aimed to characterize patterns of structural brain changes in RBD and PD patients using multimodal MRI. Methods A total of 30 patients with isolated RBD, 29 patients with PD, and 56 age-matched healthy controls (HC) underwent MRI at 3T, including tensor-based morphometry, diffusion tensor imaging, and assessment of cortical thickness. Results RBD individuals showed increased volume of the right caudate nucleus compared with HC, and higher cerebellar volume compared with both PD subjects and HC. Similar to PD subjects, RBD patients displayed increased fractional anisotropy (FA) in the corticospinal tracts, several tracts mainly related to non-motor function, and reduced FA of the corpus callosum compared with HC. Further, RBD subjects showed higher FA in the cerebellar peduncles and brainstem compared with both, PD patients and HC. PD individuals exhibited lower than normal volume in the basal ganglia, midbrain, pedunculopontine nuclei, and cerebellum. In contrast, volume in PD subjects was increased in the thalamus compared with both HC and RBD subjects. Conclusions We found convergent patterns of structural brain alterations in RBD and PD patients compared with HC. The changes observed suggest a co-occurrence of neurodegeneration and compensatory mechanisms that fail with emerging PD pathology. Our findings strengthen the hypothesis of RBD and PD constituting a continuous disease spectrum.

scholarly journals Structural Brain Alterations Associated with Rapid Eye Movement Sleep Behavior Disorder in Parkinson’s Disease

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Soufiane Boucetta ◽  
Ali Salimi ◽  
Mahsa Dadar ◽  
Barbara E. Jones ◽  
D. Louis Collins ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Eye Movement ◽  
Behavior Disorder ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Sleep Behavior ◽  
Structural Brain ◽  
Structural Brain Alterations

Parkinson’s Disease Genetic Loci in Rapid Eye Movement Sleep Behavior Disorder

2015 ◽  
Vol 56 (3) ◽  
pp. 617-622 ◽  
Author(s):  
Z. Gan-Or ◽  
S. L. Girard ◽  
A. Noreau ◽  
C. S. Leblond ◽  
J. F. Gagnon ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Eye Movement ◽  
Behavior Disorder ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Genetic Loci ◽  
Sleep Behavior

Impulse control disorder and rapid eye movement sleep behavior disorder in Parkinson's disease

2014 ◽  
Vol 20 (12) ◽  
pp. 1411-1414 ◽  
Author(s):  
Sophie Bayard ◽  
Yves Dauvilliers ◽  
Huan Yu ◽  
Muriel Croisier-Langenier ◽  
Alexia Rossignol ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Eye Movement ◽  
Impulse Control ◽  
Behavior Disorder ◽  
Impulse Control Disorder ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Sleep Behavior

Exploring the functional role and neural correlates of K-complexes in isolated rapid eye movement sleep behavior disorder

Cortex ◽  
2021 ◽  
Author(s):  
Andrea Galbiati ◽  
Giulia Carli ◽  
Elisabetta Fasiello ◽  
Francesca Casoni ◽  
Marco Zucconi ◽  
...  
Keyword(s):  
Eye Movement ◽  
Functional Role ◽  
Behavior Disorder ◽  
Neural Correlates ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Sleep Behavior

Dopamine transporter imaging deficit predicts early transition to synucleinopathy in idiopathic rapid eye movement sleep behavior disorder

2017 ◽  
Vol 82 (3) ◽  
pp. 419-428 ◽  
Author(s):  
Alex Iranzo ◽  
Joan Santamaría ◽  
Francesc Valldeoriola ◽  
Monica Serradell ◽  
Manel Salamero ◽  
...  
Keyword(s):  
Eye Movement ◽  
Dopamine Transporter ◽  
Behavior Disorder ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Sleep Behavior ◽  
Dopamine Transporter Imaging ◽  
Early Transition

scholarly journals Electromyography Analysis of Rapid Eye Movement Sleep Behavior Disorder

2018 ◽  
Vol 73 (1) ◽  
pp. 27-33
Author(s):  
Natsuko NAKANO ◽  
Fumiya KINOSHITA ◽  
Hiroki TAKADA ◽  
Meiho NAKAYAMA
Keyword(s):  
Eye Movement ◽  
Behavior Disorder ◽  
Rapid Eye Movement ◽  
Rapid Eye Movement Sleep ◽  
Sleep Behavior
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