scholarly journals Peripheral Arterial Tonometry – PAT Technology

2021 ◽  
pp. 101566
Author(s):  
Robert P. Schnall ◽  
Jacob (Koby) Sheffy ◽  
Thomas Penzel
Keyword(s):  
Peripheral Arterial Tonometry ◽  
Arterial Tonometry ◽  
Peripheral Arterial

scholarly journals Variability of Peripheral Arterial Tonometry in the Measurement of Endothelial Function in Healthy Men

2009 ◽  
Vol 32 (12) ◽  
pp. 700-704 ◽  
Author(s):  
Jianmin Liu ◽  
Jingzhu Wang ◽  
Yan Jin ◽  
Hans J. Roethig ◽  
Martin Unverdorben
Keyword(s):  
Endothelial Function ◽  
Peripheral Arterial Tonometry ◽  
Healthy Men ◽  
Arterial Tonometry ◽  
Peripheral Arterial

scholarly journals Assessment of endothelial function by non-invasive peripheral arterial tonometry predicts late cardiovascular adverse events

2010 ◽  
Vol 31 (9) ◽  
pp. 1142-1148 ◽  
Author(s):  
R. Rubinshtein ◽  
J. T. Kuvin ◽  
M. Soffler ◽  
R. J. Lennon ◽  
S. Lavi ◽  
...  
Keyword(s):  
Adverse Events ◽  
Endothelial Function ◽  
Peripheral Arterial Tonometry ◽  
Non Invasive ◽  
Arterial Tonometry ◽  
Peripheral Arterial

Abstract 11845: Impaired Peripheral Endothelial Function Assessed by Digital Reactive Hyperemia Peripheral Arterial Tonometry and Risk of In-Stent Restenosis

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Naohiro Komura ◽  
Kenichi Tsujita ◽  
Kenshi Yamanaga ◽  
Kenji Sakamoto ◽  
Takashi Miyazaki ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Prognostic Value ◽  
Reactive Hyperemia ◽  
Characteristic Analysis ◽  
Peripheral Arterial Tonometry ◽  
Stent Restenosis ◽  
Arterial Tonometry ◽  
Stent Length ◽  
Peripheral Arterial ◽  
In Stent Restenosis

Introduction: Drug-eluting stents (DESs) are replacing bare-metal stents (BMSs), but in-stent restenosis (ISR) remains a problem. Impaired endothelial function is a key event in the atherosclerosis process and a predictor of future cardiovascular events. Reactive hyperemia index (RHI) assessed by peripheral arterial tonometry (PAT) evaluates endothelial function noninvasively. Hypothesis: We prospectively assessed the prognostic value of RHI in predicting ISR after percutaneous coronary intervention (PCI). Methods: RHI was measured using Endo-PAT 2000 before PCI (initial RHI) and at follow-up angiography (F/U RHI) in 249 consecutive patients who had successful PCI. F/U angiography was performed at six and nine months after PCI with BMS and DES, respectively. ISR was defined as percent diameter stenosis >50% at F/U angiography assessed by quantitative coronary angiography. Results: At F/U, ISR was seen in 68 patients (27.3%). F/U ln(RHI) was significantly lower in patients with ISR than in those without (0.52 ± 0.23 vs. 0.65 ± 0.27, p < 0.01); no between-group difference in initial ln(RHI) was seen (0.60 ± 0.26 vs. 0.62 ± 0.25, p = 0.56). By multivariate logistic regression analysis, even after adjusting for other significant parameters in univariate analysis (BMS use, total stent length, HDL-Cholesterol, HbA1c, calcium antagonist use, and post-PCI minimum lumen diameter), F/U ln(RHI) independently predicted ISR (odds ratio: 0.13; 95% confidence interval [CI]: 0.04-0.48; p = 0.002). In receiver operating-characteristic analysis, F/U RHI was the strongest predictor of ISR (area under the curve [AUC]: 0.67; 95% CI: 0.60-0.75; p < 0.01; RHI < 1.73 had 67.6% sensitivity, 64.1% specificity); AUC significantly improved from 0.62 to 0.70 when RHI was added to traditional ISR risk factors (diabetes mellitus, total stent length, minimum stent diameter) (p = 0.02). Net reclassification index was significant after addition of RHI (26.5%, p = 0.002). Conclusions: To our knowledge, this is the first study indicating that impaired RHI at F/U angiography independently predicts occurrence of ISR. The simple and noninvasive assessment of endothelial function by RH-PAT adds incremental prognostic value to ISR-risk stratification following PCI.

Abstract 536: Poor Correlation Between FMD and PAT-Ratio in Patients With Metabolic Syndrome

2017 ◽  
Vol 37 (suppl_1) ◽  
Author(s):  
Ueda Tomohiro
Keyword(s):  
Metabolic Syndrome ◽  
Endothelial Function ◽  
Multivariable Analysis ◽  
Control Group ◽  
Poor Correlation ◽  
Study Group ◽  
Peripheral Arterial Tonometry ◽  
Arterial Tonometry ◽  
Coronary Lesions ◽  
Peripheral Arterial

Background: Flow mediated dilatation (FMD) and peripheral arterial tonometry (PAT) are commonly used methods for assessing endothelial function in a research setting but it is unclear how well they correlate. The aim of this study is to compare and correlate these methods in patients with metabolic syndrome. Methods: The study involved 105 subjects (mean age68±10 years) with metabolic syndrome. Based on the results of coronary angiography, they were divided into 2 groups: a study group with coronary lesions (n=68) and a control group without coronary lesions (n=37). Flow mediated vasodilatation (FMD) and nitroglycerine-induced vasodilatation (NID) in the brachial artery was measured by using UNEXEF18G (UNEX CO, Japan). At the same time, PAT ratio was measured by using Endo-PAT 2000 (Itamar Medical, Israel) Results: FMD was not correlated with PAT ratio by Spearman`s analysis. FMD was significantly impaired in the study group compared to that in the control group (3.9±1.8% vs. 2.6±1.5%, respectively; P<0.001). However, NID and PAT ratio had no deference in the two groups. Multivariable analysis revealed that FMD (odds ratio: 0.53, 95% confidence interval [CI]: 0.31-0.90) were independent variables for CAD in metabolic syndrome patients. Conclusion: This study showed that poor correlation between FMD and PAT in patients with metabolic syndrome. PAT may not be used as a substitute for FMD as a measure of endothelial function

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