PL-107: Should gastric bypass operation be done for type 2 diabetes in subjects with body mass index 20 - 34 kgs/m2?- an initial Indian experience

2009 ◽  
Vol 5 (3) ◽  
pp. S3
Author(s):  
Shashank S. Shah ◽  
Jayashree S. Todkar ◽  
Poonam S. Shah
2019 ◽  
Vol 229 (4) ◽  
pp. e2
Author(s):  
Bernardo M. Pessoa ◽  
Matthew G. Browning ◽  
Jad Khoraki ◽  
Guilherme Mazzini ◽  
Luke Wolfe ◽  
...  

2009 ◽  
Vol 161 (1) ◽  
pp. 201-206 ◽  
Author(s):  
Bernd Schultes ◽  
Barbara Ernst ◽  
Florian Schmid ◽  
Martin Thurnheer

ContextObesity resulting from damage to the hypothalamus, i.e. hypothalamic obesity, is a severe condition that currently lacks any effective evidence-based therapy.ObjectiveOur goal was to describe the course of hypothalamic obesity in a craniopharyngioma patient treated with distal gastric bypass surgery and to outline distinct aspects of multidisciplinary case management.Patient and methodsA 29-year-old man, who had undergone craniopharyngioma resection at the age of 8, was referred to our Interdisciplinary Obesity Centre with a body mass index (BMI) of 52.0 kg/m2, type 2 diabetes and obstructive sleep apnoea syndrome (OSAS). After careful preoperative preparation, including the adjustment of hormone substitution therapy for panhypopituitarism, nutritional counselling and a supervised exercise program, he underwent a distal gastric bypass operation.ResultsEighteen months after the operation the patient's BMI had decreased to 31.9 kg/m2, type 2 diabetes was in complete remission, and OSAS appeared to be improved. Also, feelings of hunger were markedly reduced after the operation. A standard regimen of supplements successfully prevented any severe nutritional deficiencies. After weight loss, the dose of hydrocortisone could be distinctly reduced without any signs of adrenal insufficiency while GH substitution had to be markedly increased to achieve normal IGF1 levels.ConclusionsOur case demonstrates that within a multidisciplinary team approach, a distal gastric bypass operation can be a safe and highly effective therapy for patients with hypothalamic obesity. Also, our findings hint at an effect of gastric bypass surgery on hunger and eating behaviour that may not essentially rely on hypothalamic mechanisms.


2018 ◽  
Vol 86 (March) ◽  
pp. 255-263
Author(s):  
MOHAMED SHETIWY, M.D. NASHAT ABD EL-RAZEK, M.D. ◽  
HOSAM EL-GHADBAN, M.D., M.R.Cs. ASHRAF ABBAS, M.D. ◽  
AHMED NEGM, M.D. MOHAMED SAMIR, M.D., M.R.Cs. ◽  
MAGDY BASHEER, M.D. ABD EL-RAHMAN EL-BAHY, M.D. ◽  
ASHRAF SHOMA, M.D., F.R.Cs.

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