Eating-related pathology at the intersection of gender, gender expression, sexual orientation, and weight status: An intersectional Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA) of the Growing Up Today Study cohorts

2021 ◽  
pp. 114092
Author(s):  
Ariel L. Beccia ◽  
Jonggyu Baek ◽  
S. Bryn Austin ◽  
William M. Jesdale ◽  
Kate L. Lapane
BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e036130
Author(s):  
Merida Rodriguez-Lopez ◽  
Juan Merlo ◽  
Raquel Perez-Vicente ◽  
Peter Austin ◽  
George Leckie

ObjectiveTo describe a novel strategy, Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA) to evaluate hospital performance, by analysing differences in 30-day mortality after a first-ever acute myocardial infarction (AMI) in Sweden.DesignCross-classified study.Setting68 Swedish hospitals.Participants43 247 patients admitted between 2007 and 2009, with a first-ever AMI.Primary and secondary outcome measuresWe evaluate hospital performance by analysing differences in 30-day mortality after a first-ever AMI using a cross-classified multilevel analysis. We classified the patients into 10 categories according to a risk score (RS) for 30-day mortality and created 680 strata defined by combining hospital and RS categories.ResultsIn the cross-classified multilevel analysis the overall RS adjusted hospital 30-day mortality in Sweden was 4.78% and the between-hospital variation was very small (variance partition coefficient (VPC)=0.70%, area under the curve (AUC)=0.54). The benchmark value was therefore achieved by all hospitals. However, as expected, there were large differences between the RS categories (VPC=34.13%, AUC=0.77)ConclusionsMAIHDA is a useful tool to evaluate hospital performance. The benefit of this novel approach to adjusting for patient RS is that it allowed one to estimate separate VPCs and AUC statistics to simultaneously evaluate the influence of RS categories and hospital differences on mortality. At the time of our analysis, all hospitals in Sweden were performing homogeneously well. That is, the benchmark target for 30-day mortality was fully achieved and there were not relevant hospital differences. Therefore, possible quality interventions should be universal and oriented to maintain the high hospital quality of care.


PLoS ONE ◽  
2018 ◽  
Vol 13 (12) ◽  
pp. e0208624 ◽  
Author(s):  
Aránzazu Hernández-Yumar ◽  
Maria Wemrell ◽  
Ignacio Abásolo Alessón ◽  
Beatriz González López-Valcárcel ◽  
George Leckie ◽  
...  

2021 ◽  
pp. 140349482098149
Author(s):  
Maria Wemrell ◽  
Cecilia Lenander ◽  
Kristofer Hansson ◽  
Raquel Vicente Perez ◽  
Katarina Hedin ◽  
...  

Aims: Antimicrobial resistance presents an increasingly serious threat to global public health, which is directly related to how antibiotic medication is used in society. Actions aimed towards the optimised use of antibiotics should be implemented on equal terms and according to the needs of the population. Previous research results on differences in antibiotic use between socio-economic and demographic groups in Sweden are not entirely coherent, and have typically focused on the effects of singular socio-economic variables. Using an intersectional approach, this study provides a more precise analysis of how the dispensation of antibiotic medication was distributed across socio-economic and demographic groups in Sweden in 2016–2017. Methods: Using register data from a nationwide cohort and adopting an intersectional analysis of individual heterogeneity and discriminatory accuracy, we map the dispensation of antibiotics according to age, sex, country of birth and income. Results: While women and high-income earners had the highest antibiotic dispensation prevalence, no large differences in the dispensation of antibiotics were identified between socio-economic groups. Conclusions: Public-health interventions aiming to support the reduced and optimised use of antibiotics should be directed towards the whole Swedish population rather than towards specific groups. Correspondingly, an increased focus on socio-economic or demographic factors is not warranted in interventions aimed at improving antibiotic prescription patterns among medical practitioners.


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