Influence of chemical nature of carrier materials on the dissolution behavior of racemic ibuprofen

2018 ◽  
Vol 132 ◽  
pp. 91-98 ◽  
Author(s):  
Sarah Reiser ◽  
Miaotian Sun ◽  
Monika Johannsen ◽  
Michael Türk
Author(s):  
Richard R. Shivers

The sinus gland is a neurohemal organ located in the crayfish eyestalk and represents a storage site for neurohormones prior to their release into the circulation. The sinus gland contains 3 classes of dense, membrane-limited granules: 1) granules measuring less than 1000 Å in diameter, 2) granules measuring 1100-1400 Å in diameter, and 3) granules measuring 1500-2000 Å in diameter. Class 3 granules are the most electron-dense of the granules found in the sinus gland, while class 2 granules are the most abundant. Generally, all granules appear to undergo similar changes during release.Release of neurosecretory granules may be initiated by a preliminary fragmentation of the “parent granule” into smaller, less dense vesicles which measure about 350 Å in diameter (V, Figs. 1-3). A decrease in density of the granules prior to their fragmentation has been observed and may reflect a change in the chemical nature of the granule contents.


Author(s):  
Nicholas J Severs

In his pioneering demonstration of the potential of freeze-etching in biological systems, Russell Steere assessed the future promise and limitations of the technique with remarkable foresight. Item 2 in his list of inherent difficulties as they then stood stated “The chemical nature of the objects seen in the replica cannot be determined”. This defined a major goal for practitioners of freeze-fracture which, for more than a decade, seemed unattainable. It was not until the introduction of the label-fracture-etch technique in the early 1970s that the mould was broken, and not until the following decade that the full scope of modern freeze-fracture cytochemistry took shape. The culmination of these developments in the 1990s now equips the researcher with a set of effective techniques for routine application in cell and membrane biology.Freeze-fracture cytochemical techniques are all designed to provide information on the chemical nature of structural components revealed by freeze-fracture, but differ in how this is achieved, in precisely what type of information is obtained, and in which types of specimen can be studied.


1998 ◽  
Vol 08 (PR5) ◽  
pp. Pr5-85-Pr5-89
Author(s):  
P. Sarrazin ◽  
F. Bernard ◽  
G. Calvarin ◽  
J. C. Niepce ◽  
B. Thierry

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Yuhan Sun

Abstract: In order to reveal the dissolution behavior of iron tailings in blast furnace slag, we studied the main component of silica in iron tailings. First, edge contour features need to be established to represent the melting process of silica. We choose shape, perimeter, area and generalized radius as objects. By independently analyzing the influence of these four indexes on the melting rate, the area and shape were selected as the characteristic parameters of the edge contour of the silica particles. Then, the actual melting rate of the silica is estimated by the edge contour feature index. Finally, we can calculate the melting rate of the first second of three time periods of 0.00010312mm3/s,0.0002399mm3/s,0.0000538mm3/s.


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