The clinical impact of malnutrition on the postoperative outcomes of patients undergoing colorectal resection surgery for colon or rectal cancer: Propensity score matched analysis of 2011–2017 US hospitals

2021 ◽  
Vol 38 ◽  
pp. 101587
Author(s):  
David Uihwan Lee ◽  
Gregory Hongyuan Fan ◽  
David Jeffrey Hastie ◽  
Elyse Ann Addonizio ◽  
Julie Suh ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Propensity Score ◽  
Colorectal Resection ◽  
Clinical Impact ◽  
Postoperative Outcomes

The clinical impact of cirrhosis on the postoperative outcomes of patients undergoing bariatric surgery: propensity score-matched analysis of 2011-2017 US hospitals

2021 ◽  
pp. 1-10
Author(s):  
David Uihwan Lee ◽  
Gregory Hongyuan Fan ◽  
David Jeffrey Hastie ◽  
Elyse Ann Addonizio ◽  
Vibhav Narayan Prakasam ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Propensity Score ◽  
Clinical Impact ◽  
Postoperative Outcomes

The clinical impact of frailty on the postoperative outcomes of patients undergoing gastrectomy for gastric cancer: a propensity-score matched database study

2021 ◽  
Author(s):  
David Uihwan Lee ◽  
Jean Kwon ◽  
John Han ◽  
Gregory Hongyuan Fan ◽  
David Jeffrey Hastie ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Propensity Score ◽  
Clinical Impact ◽  
Postoperative Outcomes ◽  
Database Study

Evaluating disparities in delivery of neoadjuvant guideline‐based chemoradiation for rectal cancer: A multicenter, propensity score‐weighted cohort study

2021 ◽  
Author(s):  
Lung W. Lau ◽  
William C. Kethman ◽  
Katherine E. Bingmer ◽  
Asya Ofshteyn ◽  
Emily Steinhagen ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Cohort Study ◽  
Propensity Score

scholarly journals Postoperative non-steroidal anti-inflammatory drug use and oncological outcomes of rectal cancer

BJS Open ◽  
2021 ◽  
Vol 5 (1) ◽  
Author(s):  
O Grahn ◽  
M Lundin ◽  
M-L Lydrup ◽  
E Angenete ◽  
M Rutegård
Keyword(s):  
Rectal Cancer ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Instrumental Variables ◽  
Cox Regression ◽  
Recurrence Free Survival ◽  
Free Survival ◽  
Oncological Outcomes ◽  
Anti Inflammatory ◽  
Instrumental Variables Approach

Abstract Background Non-steroidal anti-inflammatory drugs (NSAIDs) are known to suppress the inflammatory response after surgery and are often used for pain control. This study aimed to investigate NSAID use after radical surgical resection for rectal cancer and long-term oncological outcomes. Methods A cohort of patients who underwent anterior resection for rectal cancer between 2007 and 2013 in 15 hospitals in Sweden was investigated retrospectively. Data were obtained from the Swedish Colorectal Cancer Registry and medical records; follow-up was undertaken until July 2019. Patients who received NSAID treatment for at least 2 days after surgery were compared with controls who did not, and the primary outcome was recurrence-free survival. Cox regression modelling with confounder adjustment, propensity score matching, and an instrumental variables approach were used; missing data were handled by multiple imputation. Results The cohort included 1341 patients, 362 (27.0 per cent) of whom received NSAIDs after operation. In analyses using conventional regression and propensity score matching, there was no significant association between postoperative NSAID use and recurrence-free survival (adjusted hazard ratio (HR) 1.02, 0.79 to 1.33). The instrumental variables approach, including individual hospital as the instrumental variable and clinicopathological variables as co-variables, suggested a potential improvement in the NSAID group (HR 0.61, 0.38 to 0.99). Conclusion Conventional modelling did not demonstrate an association between postoperative NSAID use and recurrence-free survival in patients with rectal cancer, although an instrumental variables approach suggested a potential benefit.

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