Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl ethyl sulfide is associated with increased production of reactive oxygen species

Nadph Cytochrome ◽

P450 Reductase ◽

Generation of Reactive Oxygen Species during Interaction of Diesel Exhaust Particle Components with NADPH-Cytochrome p450 Reductase and Involvement of the Bioactivation in the DNA Damage

Free Radical Biology and Medicine ◽

10.1016/s0891-5849(96)00341-3 ◽

1997 ◽

Vol 22 (3) ◽

pp. 479-487 ◽

Cited By ~ 174

Author(s):

Yoshito Kumagai ◽

Toyoko Arimoto ◽

Masaru Shinyashiki ◽

Nobuhiro Shimojo ◽

Yumi Nakai ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Cytochrome P450 ◽

Diesel Exhaust ◽

Reactive Oxygen ◽

Diesel Exhaust Particle ◽

Oxygen Species ◽

Nadph Cytochrome ◽

Effects of transient overexpression or knockdown of cytochrome P450 reductase on reactive oxygen species generation and hypoxia reoxygenation injury in liver cells

Clinical and Experimental Pharmacology and Physiology ◽

10.1111/j.1440-1681.2011.05622.x ◽

2011 ◽

Vol 38 (12) ◽

pp. 846-853 ◽

Cited By ~ 8

Author(s):

Venkateswaran C Pillai ◽

Russell O Snyder ◽

Upendra Gumaste ◽

Thomas J Thekkumkara ◽

Reza Mehvar

Keyword(s):

Reactive Oxygen Species ◽

Cytochrome P450 ◽

Reactive Oxygen Species Generation ◽

Reactive Oxygen ◽

Liver Cells ◽

Oxygen Species ◽

P450 Reductase ◽

Reoxygenation Injury ◽

Transient Overexpression

Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)67801-4 ◽

1991 ◽

Vol 266 (6) ◽

pp. 3372-3375

Author(s):

T Shimizu ◽

T Tateishi ◽

M Hatano ◽

Y Fujii-Kuriyama

Keyword(s):

Cytochrome P450 ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Catalytic Function ◽

The cytochrome P450 2B4-NADPH cytochrome P450 reductase electron transfer complex is not formed by charge-pairing.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42093-5 ◽

1992 ◽

Vol 267 (21) ◽

pp. 14669-14676

Author(s):

A.I. Voznesensky ◽

J.B. Schenkman

Keyword(s):

Electron Transfer ◽

Cytochrome P450 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Nadph Cytochrome P450 Reductase ◽

Electron Transfer Complex

Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase. Implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32834fcf4f ◽

2012 ◽

Vol 23 (4) ◽

pp. 393-405 ◽

Cited By ~ 5

Author(s):

Dorota Kostrzewa-Nowak ◽

Bohdan Bieg ◽

Mark J.I. Paine ◽

C. Roland Wolf ◽

Jolanta Tarasiuk

Keyword(s):

Cytochrome P450 ◽

Multidrug Resistant ◽

Structural Factors ◽

Hl60 Cells ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anthraquinone Derivatives ◽

Organization of NADPH-Cytochrome P450 Reductase and CYP1A2 in the Endoplasmic Reticulum—Microdomain Localization Affects Monooxygenase Function

Molecular Pharmacology ◽

10.1124/mol.110.068817 ◽

2010 ◽

Vol 79 (3) ◽

pp. 549-557 ◽

Cited By ~ 24

Author(s):

Lauren Brignac-Huber ◽

James R. Reed ◽

Wayne L. Backes

Keyword(s):

Endoplasmic Reticulum ◽

Cytochrome P450 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Role of the prosthetic groups of NADPH-cytochrome P450 reductase in 3-hydroxyanthranilamide-catalyzed, NADPH-dependent superoxide anion production

Redox Report ◽

10.1080/13510002.1996.11747070 ◽

1996 ◽

Vol 2 (5) ◽

pp. 339-344

Author(s):

Y. Ohta ◽

R. Shinohara ◽

I. Ishiguro

Keyword(s):

Cytochrome P450 ◽

Superoxide Anion ◽

Superoxide Anion Production ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anion Production ◽

Nadph Cytochrome P450 Reductase ◽

Prosthetic Groups

Reduction of cytochrome b5 by NADPH–cytochrome P450 reductase

Archives of Biochemistry and Biophysics ◽

10.1016/j.abb.2005.06.019 ◽

2005 ◽

Vol 440 (2) ◽

pp. 204-211 ◽

Cited By ~ 56

Author(s):

F. Peter Guengerich

Keyword(s):

Cytochrome P450 ◽

Cytochrome B5 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Altered heme catabolism by heme oxygenase-1 caused by mutations in human NADPH cytochrome P450 reductase

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2010.08.072 ◽

2010 ◽

Vol 400 (3) ◽

pp. 374-378 ◽

Cited By ~ 26

Author(s):

Amit V. Pandey ◽

Christa E. Flück ◽

Primus E. Mullis

Keyword(s):

Cytochrome P450 ◽

Heme Oxygenase ◽

Heme Oxygenase 1 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Membrane Topology of NADPH–Cytochrome P450 Reductase on the Endoplasmic Reticulum

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1997.0553 ◽

1998 ◽

Vol 351 (2) ◽

pp. 175-179 ◽

Cited By ~ 22

Author(s):

Yuichiro Kida ◽

Satoru Ohgiya ◽

Katsuyoshi Mihara ◽

Masao Sakaguchi

Keyword(s):

Endoplasmic Reticulum ◽

Cytochrome P450 ◽

Membrane Topology ◽

Nadph Cytochrome ◽

P450 Reductase ◽