Spectrochromatographic determination of dorzolamide hydrochloride and timolol maleate in an ophthalmic solution using three-way analysis methods

Talanta ◽  
2019 ◽  
Vol 191 ◽  
pp. 248-256 ◽  
Author(s):  
Erdal Dinç ◽  
Eda Büker
Author(s):  
Willem Talakua ◽  
Eygner Gerald Talakua

The purpose of this study is to study the maximization of business profits through the determination of the optimal use of production factors in the trawl ring business in Latuhalat. Observations and direct interviews based on questionnaires were carried out on 3 fishermen who owned trawl ring businesses in 3 hamlets in Latuhalat. Data were analyzed using business profit analysis methods and linear programming analysis. The results showed that: 1). The optimal use of production factors for trawling by the respondents in Latuhalat is 41 - 45 trips in June using 15.2 - 21.1 liters of gasoline, 280.9 - 304.4 liters of gasoline, 10.1 - 21 , 2 liters of oil, using labor as much as 15-17 people for 8 hours / day, and using transportation and FAD services as much as 351.3 - 360 HOK or 8 hours per day; and 2). The maximum profit that can be obtained from trawling rings by respondents in Latuhalat is Rp. 165,545,500 - up to Rp. 184,800,000, - in June. To achieve this maximum profit, respondents need to produce 25,270.3 kg of fish to 27,540.98 kg in June.


Kerntechnik ◽  
2008 ◽  
Vol 73 (3) ◽  
pp. 118-121
Author(s):  
T. Heinrich ◽  
L. Funke ◽  
M. Köhler ◽  
U.-K. Schkade ◽  
F. Ullrich ◽  
...  

2020 ◽  
Vol 16 ◽  
Author(s):  
Aykut Kul ◽  
Murat Ozdemir ◽  
Selma Ozilhan ◽  
Olcay Sagirli

Background: Buprenorphine is quite common in the illicit market. Buprenorphine-containing drugs abuse is frequently encountered in patients. The analysis methods used to determine the abuse of buprenorphine and norbuprenorphine are important for forensic science. Buprenorphine is metabolized to norbuprenorphine by the liver. Objective: Therefore, the determination of buprenorphine and norbuprenorphine in urine is one of the methods to determine the abuse of buprenorphine. Methods: In this study, we have developed a precise, simple, and rapid ultra-performance liquid chromatographytandem mass spectrometer method for the determination of buprenorphine and norbuprenorphine simultaneously. Results: The developed method was validated in terms of selectivity and linearity, which was in the range of 9–1800 ng/mL for both buprenorphine and norbuprenorphine. The intra-assay and inter-assay accuracy and precision were found within acceptable limits of the EMA guideline. Lower limits of quantitation were 9 ng/mL for both buprenorphine and norbuprenorphine. Conclusion: The developed method was successfully applied for the determination of both analytes in the proficiency testing samples.


2021 ◽  
Vol 68 (3-4) ◽  
pp. 22-28
Author(s):  
Bettina Ronai ◽  
Rainer Franz ◽  
Marcella Frauscher

Water and solid particulate contamination are the two most common contaminants of lubricated systems and may be highly problematic for these systems. To reduce downtime and prevent failure, lubricant formulations contain detergent and dispersant additives that play an important role in terms of contamination tolerance. In lack of a practical procedure for the determination of the relevant properties, a novel method for the evaluation of the dispersing ability of lubricating oils is introduced. Following and combining established lubricant analysis methods, a procedure with optimum parameters was found. An assessment of the method using fresh and artificially altered lubricating oils allowed a differentiation concerning their dispersing ability.


Sign in / Sign up

Export Citation Format

Share Document