Target-triggered activation of rolling circle amplification for label-free and sensitive fluorescent uracil-DNA glycosylase activity detection and inhibition

Talanta ◽  
2019 ◽  
Vol 204 ◽  
pp. 812-816 ◽  
Author(s):  
Fang Yang ◽  
Xia Li ◽  
Jing Li ◽  
Yun Xiang ◽  
Ruo Yuan
Keyword(s):  
Rolling Circle Amplification ◽  
Dna Glycosylase ◽  
Label Free ◽  
Activity Detection ◽  
Uracil Dna Glycosylase ◽  
Rolling Circle

Label-free and sensitive detection of uracil-DNA glycosylase using exponential real-time rolling circle amplification

2018 ◽  
Vol 10 (20) ◽  
pp. 2405-2410 ◽  
Author(s):  
Yuan Xu ◽  
Yun-Xi Cui ◽  
Qiu-Ge Zhao ◽  
An-Na Tang ◽  
De-Ming Kong
Keyword(s):  
Real Time ◽  
Rolling Circle Amplification ◽  
Sensitive Detection ◽  
Dna Glycosylase ◽  
Label Free ◽  
Uracil Dna Glycosylase ◽  
Schematic Representation ◽  
Rolling Circle ◽  
Sensing Platform ◽  
Activity Sensing

Schematic representation of an exponential rolling circle amplification-based uracil-DNA glycosylase activity-sensing platform.

Target-responsive dumbbell probe-mediated rolling circle amplification strategy for highly sensitive Hg2+ detection

RSC Advances ◽  
2014 ◽  
Vol 4 (51) ◽  
pp. 27091-27097 ◽  
Author(s):  
Qingwang Xue ◽  
Yanqin Lv ◽  
Yuanfu Zhang ◽  
Shuling Xu ◽  
Qiaoli Yue ◽  
...  
Keyword(s):  
Rolling Circle Amplification ◽  
Selective Detection ◽  
Label Free ◽  
Rolling Circle ◽  
Fluorescent Sensing ◽  
Highly Sensitive ◽  
Mercuric Ions ◽  
Amplification Strategy

A novel label-free amplified fluorescent sensing scheme based on target-responsive dumbbell probe-mediated rolling circle amplification (D-RCA) has been developed for sensitive and selective detection of mercuric ions.

Sensitive and label-free discrimination of 5-hydroxymethylcytosine and 5-methylcytosine in DNA by ligation-mediated rolling circle amplification

2018 ◽  
Vol 54 (62) ◽  
pp. 8602-8605 ◽  
Author(s):  
Zi-yue Wang ◽  
Meng Wang ◽  
Yan Zhang ◽  
Chun-yang Zhang
Keyword(s):  
Rolling Circle Amplification ◽  
Fluorescence Method ◽  
Label Free ◽  
Rolling Circle

We develop a label-free fluorescence method for sensitive discrimination of 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) by ligation-mediated rolling circle amplification.

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