A rapid, adaptative DNA biosensor based on molecular beacon-concatenated dual signal amplification strategies for ultrasensitive detection of p53 gene and cancer cells

Talanta ◽  
2020 ◽  
Vol 210 ◽  
pp. 120638 ◽  
Author(s):  
Zewei Luo ◽  
Ya Xu ◽  
Zhijun Huang ◽  
Junman Chen ◽  
Xiaqing Wang ◽  
...  
2020 ◽  
Vol 150 ◽  
pp. 111895 ◽  
Author(s):  
Liying Zhao ◽  
Huaixia Yang ◽  
Xiaoke Zheng ◽  
Jinge Li ◽  
Lihe Jian ◽  
...  

2016 ◽  
Vol 8 (47) ◽  
pp. 8262-8265 ◽  
Author(s):  
Ke Yang ◽  
Ming Zeng ◽  
Xing He ◽  
Jianming Li ◽  
Dinggeng He

An enzyme-free dual signal amplification strategy based on programmable molecular hairpins has been developed for amplified detection of DNA via the hairpin DNA-fueled dynamic self-assembly of three-arm DNAzyme.


2018 ◽  
Vol 10 (48) ◽  
pp. 5834-5841 ◽  
Author(s):  
Hao Liu ◽  
Jialong Fan ◽  
Weiping Liu ◽  
Chunyi Tong ◽  
Zhenhua Xie ◽  
...  

Due to the miRNA's key roles in early disease diagnosis, an assay based on chimeric molecular beacon was constructed for miR204 detection with LOD lower to 50 pM.


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