scholarly journals HER2 breast cancer biomarker detection using a sandwich optical fiber assay

Talanta ◽  
2021 ◽  
Vol 221 ◽  
pp. 121452 ◽  
Author(s):  
Médéric Loyez ◽  
Maxime Lobry ◽  
Eman M. Hassan ◽  
Maria C. DeRosa ◽  
Christophe Caucheteur ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Optical Fiber ◽  
Cancer Biomarker ◽  
Biomarker Detection ◽  
Her2 Breast Cancer

scholarly journals Graphene-Coated Optical Fiber SPR Biosensor for BRCA1 and BRCA2 Breast Cancer Biomarker Detection: a Numerical Design-Based Analysis

2019 ◽  
Vol 10 (1) ◽  
pp. 67-79 ◽  
Author(s):  
Md. Biplob Hossain ◽  
Md. Muztahidul Islam ◽  
Lway Faisal Abdulrazak ◽  
Md. Masud Rana ◽  
Tarik Bin Abdul Akib ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Optical Fiber ◽  
Cancer Biomarker ◽  
Biomarker Detection ◽  
Brca1 And Brca2 ◽  
Spr Biosensor ◽  
Numerical Design

scholarly journals Optical multiplexed bioassays on photonic crystals for breast cancer biomarker detection

2021 ◽  
Vol 255 ◽  
pp. 13003
Author(s):  
Tommaso Pileri ◽  
Alberto Sinibaldi ◽  
Agostino Occhicone ◽  
Elena Giordani ◽  
Matteo Allegretti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Specific Interaction ◽  
Fluorescence Emission ◽  
Optical Biosensor ◽  
Cancer Biomarker ◽  
Time Development ◽  
Biomarker Detection ◽  
Label Free ◽  
One Dimensional ◽  
Protein Bovine Serum Albumin

An optical biosensor for proteomic breast cancer biomarker detection in complex media is presented. Bloch Surface Waves (BSW) excited onto one dimensional photonic crystal (1DPC) were used to probe the interaction of HER2 with three antibody species and an inert protein (Bovine Serum Albumin - BSA). The optical system combines Label-Free readings to track the bioassay real-time development and Fluorescence emission quantification to evaluate the level of specific interaction between the antigen and the antibodies. The results confirm a distinguishable level of affinity between the antibodies and the analyte according to their specificity even at low antibody surface density (about 1173 pg/mm2).

scholarly journals Breast cancer biomarker detection through the photoluminescence of epitaxial monolayer MoS2 flakes

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Sergio Catalán-Gómez ◽  
María Briones ◽  
Sandra Cortijo-Campos ◽  
Tania García-Mendiola ◽  
Alicia de Andrés ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Spectroscopic Analysis ◽  
Optical Biosensor ◽  
Cancer Biomarker ◽  
Dna Probe ◽  
Optical Biosensors ◽  
Biomarker Detection ◽  
Monolayer Mos2 ◽  
Complementary Sequence

Abstract In this work we report on the characterization and biological functionalization of 2D MoS2 flakes, epitaxially grown on sapphire, to develop an optical biosensor for the breast cancer biomarker miRNA21. The MoS2 flakes were modified with a thiolated DNA probe complementary to the target biomarker. Based on the photoluminescence of MoS2, the hybridization events were analyzed for the target (miRNA21c) and the control non-complementary sequence (miRNA21nc). A specific redshift was observed for the hybridization with miRNA21c, but not for the control, demonstrating the biomarker recognition via PL. The homogeneity of these MoS2 platforms was verified with microscopic maps. The detailed spectroscopic analysis of the spectra reveals changes in the trion to excitation ratio, being the redshift after the hybridization ascribed to both peaks. The results demonstrate the benefits of optical biosensors based on MoS2 monolayer for future commercial devices.

Disposable Microfluidic Immunoarray Device for Sensitive Breast Cancer Biomarker Detection

2017 ◽  
Vol 9 (33) ◽  
pp. 27433-27440 ◽  
Author(s):  
Ricardo A. G. de Oliveira ◽  
Elsa M. Materon ◽  
Matias E. Melendez ◽  
André L. Carvalho ◽  
Ronaldo C. Faria
Keyword(s):  
Breast Cancer ◽  
Cancer Biomarker ◽  
Biomarker Detection

Catalytic Au/PEDOT/Pt micromotors for cancer biomarker detection and potential breast cancer treatment

2021 ◽  
Author(s):  
Gozde Yurdabak Karaca ◽  
Filiz Kuralay ◽  
Ozlem Bingol Ozakpinar ◽  
Emre Uygun ◽  
Umran Koc ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Breast Cancer Treatment ◽  
Cancer Biomarker ◽  
Biomarker Detection

scholarly journals Graphene oxide–metal nanocomposites for cancer biomarker detection

RSC Advances ◽  
2017 ◽  
Vol 7 (57) ◽  
pp. 35982-35991 ◽  
Author(s):  
Md. Azahar Ali ◽  
Chandan Singh ◽  
Saurabh Srivastava ◽  
Prasad Admane ◽  
Ved V. Agrawal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Graphene Oxide ◽  
Black Pepper ◽  
Cancer Biomarker ◽  
Biomarker Detection ◽  
Reduced Graphene ◽  
Metal Nanocomposites ◽  
Universal Protocol ◽  
Graphene Oxide Sheets

We report a universal protocol for the in situ bioinspired green synthesis of metal nanoparticles on simultaneously reduced graphene oxide sheets using a black pepper extract for quantification of breast cancer biomarker.

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