Experimental approach for an in vitro toxicity assay with non-aggregated quantum dots

2009 ◽  
Vol 23 (5) ◽  
pp. 955-962 ◽  
Author(s):  
Brian A. Koeneman ◽  
Yang Zhang ◽  
Kiril Hristovski ◽  
Paul Westerhoff ◽  
Yongsheng Chen ◽  
...  
ACS Nano ◽  
2012 ◽  
Vol 6 (11) ◽  
pp. 9475-9484 ◽  
Author(s):  
Wesley E. Smith ◽  
Jessica Brownell ◽  
Collin C. White ◽  
Zahra Afsharinejad ◽  
Jesse Tsai ◽  
...  

Polyhedron ◽  
2014 ◽  
Vol 70 ◽  
pp. 77-84 ◽  
Author(s):  
José S. Casas ◽  
María S. García-Tasende ◽  
Agustín Sánchez ◽  
Ángeles Sánchez-González ◽  
José Sordo ◽  
...  

2012 ◽  
Vol 9 (1) ◽  
pp. 171-174 ◽  
Author(s):  
Jun'An Liu ◽  
Xiaolei Wei ◽  
Jianhua Cao ◽  
Hong Jiang

Water soluble CdTe quantum dots have shown potential as a platform for development of live cell imaging, but their cytotoxicity limits their biological applications. To decrease their cytotoxicity, an approach to modify CdTe quantum dots (QDs) with polyamidoamine (PAMAM) was employed by forming covalent bonds between them. The resultant nanocomposites as a cell imaging bioprobe for live PK15 and their in vitro toxicity were also investigated. The results showed that the prepared nanocomposites were able to enter PK15 cells with good biocompatibility and low cellular toxicity.


1987 ◽  
Vol 13 (6) ◽  
pp. 662-668 ◽  
Author(s):  
Debra L. Skelnik ◽  
Richard L. Lindstrom ◽  
Liaquat Allarakhia ◽  
Charmille Tamulinas ◽  
O. J. Lorenzetti

2019 ◽  
Vol 38 (5) ◽  
pp. 357-384 ◽  
Author(s):  
Olusola B. Adewale ◽  
Hajierah Davids ◽  
Lynn Cairncross ◽  
Saartjie Roux

Potential applications of gold nanoparticles in biomedicine have increasingly been reported on account of the ease of synthesis, bioinert characteristics, optical properties, chemical stability, high biocompatibility, and specificity. The safety of these particles remains a great concern, as there are differences among toxicity study protocols used. This article focuses on integrating results of research on the toxicological behavior of gold nanoparticles. This can be influenced by the physicochemical properties, including size, shape, surface charge, and other factors, such as methods used in the synthesis of gold nanoparticles, models used, dose, in vivo route of administration, and interference of gold nanoparticles with in vitro toxicity assay systems. Several researchers have reported toxicological studies with regard to gold nanoparticles, using various in vitro, in vivo, and in ovo models. The conflicting results concerning the toxicity of gold nanoparticles should thus be addressed to justify the safe use of gold nanoparticles in biomedicine.


Luminescence ◽  
2015 ◽  
Vol 31 (2) ◽  
pp. 341-347 ◽  
Author(s):  
Vivek Pandey ◽  
Gajanan Pandey ◽  
Vinay Kumar Tripathi ◽  
Sapna Yadav ◽  
Mohana Krishna Reddy Mudiam

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