The role of plasma transfusion in pre-hospital haemostatic resuscitation

We present a case of transfusion-related acute lung injury as a complication of convalescent plasma transfusion in a patient who presented with COVID-19–related severe acute respiratory syndrome. Despite treatment with tocilizumab, remdesivir, and intravenous steroids, worsening dyspnea prompted adjunctive treatment with convalescent plasma. Two hours after completion of the plasma transfusion, the patient developed hypoxia-induced cardiac arrest secondary to transfusion-related acute lung injury. This case sheds light on life-threatening transfusion reactions and emphasizes the need to investigate post-transfusion monitoring protocols as well as the possible role of surveillance equipment.

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Severe COVID-19 in a Postpartum Woman: A Three-Month Challenge with Convalescent Plasma and Corticosteroid

Frontiers in Emergency Medicine ◽

10.18502/fem.v5i4.6699 ◽

2021 ◽

Author(s):

Zahra Soleimani ◽

Sedigheh Hantoushzadeh ◽

Azam Soleimani

Keyword(s):

Respiratory Function ◽

Postpartum Woman ◽

Plasma Transfusion ◽

Case Presentation ◽

Healthy Neonate ◽

Rescue Treatment ◽

Pregnancy And Postpartum ◽

Seriously Ill Patients ◽

Seriously Ill

Introduction: Management of seriously ill patients infected with new corona virus (SARS-CoV-2) is challenging especially in pregnancy and postpartum state. Case presentation: A 39- year-old primigravid critically ill woman with acute respiratory distress (ARDS) due to confirmed SARS-CoV-2 infection underwent urgent cesarean delivery (a healthy neonate) at 33 weeks and 5/7 of pregnancy. She received treatments including hydroxychloroquine, antivirals and broad-spectrum antibiotics while she was intubated for mechanical ventilation. In spite of all treatments, she developed a critical course after the mild primary clinical improvement. Convalescent plasma transfusion as a rescue treatment was performed and led to an improvement in her general condition and delayed gradual recovery in respiratory function after two months. Conclusion: The promising role of early treatment with convalescent plasma transfusion in seriously ill pregnant women infected with SARS-CoV-2, needs to be elucidated by further randomized studies.

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Facts and challenges in convalescent plasma therapy in COVID-19

10.17727/jmsr.2020/8s1-14 ◽

2020 ◽

Vol 8 (S1) ◽

pp. 112-116

Author(s):

Kumar H

Keyword(s):

Clinical Study ◽

Mortality Rate ◽

High Mortality ◽

Safety Profile ◽

Passive Immunization ◽

Scientific Data ◽

Plasma Transfusion ◽

Plasma Therapy ◽

Plasma Donation

The present coronavirus disease 2019 (COVID-19) pandemic has brought the focus back onto the passive immunization potential of the Convalescent plasma. This however has many challenges as availability of recovered patients as donors, eligibility of recovered patients for convalescent plasma donation, Safety profile of convalescent plasma. Considering the lack of efficacious treatments for COVID 19 and the epidemic situation with high mortality rate, the evaluation of convalescent plasma therapy in COVID-19 is the need of the hour. In this article, the feasibility and challenges are discussed based on the literature published on role of convalescent plasma therapy in COVID-19. Based on the limited scientific data available, convalescent plasma transfusion (CPT) therapy in COVID-19 patients appears safe, clinically effective, and reduces mortality. However an ongoing clinical study at our Centre should give us a good direction to establish the efficacy of CPT to COVID-19 patients. Keywords: convalescent plasma therapy; COVID-19; coronavirus; SARS-CoV-2

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Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽

10.1001/jama.195.12.1005 ◽

1966 ◽

Vol 195 (12) ◽

pp. 1005-1009 ◽

Cited By ~ 18

Author(s):

D. J. Fernbach

Keyword(s):

Wilms Tumor

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Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽

10.1001/jama.195.3.167 ◽

1966 ◽

Vol 195 (3) ◽

pp. 167-172 ◽

Cited By ~ 2

Author(s):

T. E. Van Metre

Keyword(s):

Diagnosis And Management

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The power of norms to sway fused group members

Behavioral and Brain Sciences ◽

10.1017/s0140525x18001644 ◽

2018 ◽

Vol 41 ◽

Cited By ~ 1

Author(s):

Winnifred R. Louis ◽

Craig McGarty ◽

Emma F. Thomas ◽

Catherine E. Amiot ◽

Fathali M. Moghaddam

Keyword(s):

Evolutionary Anthropology ◽

Normative Systems ◽

Violent Extremism ◽

Identity Fusion ◽

Group Members

AbstractWhitehouse adapts insights from evolutionary anthropology to interpret extreme self-sacrifice through the concept of identity fusion. The model neglects the role of normative systems in shaping behaviors, especially in relation to violent extremism. In peaceful groups, increasing fusion will actually decrease extremism. Groups collectively appraise threats and opportunities, actively debate action options, and rarely choose violence toward self or others.

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Elaborating the role of reflection and individual differences in the study of folk-economic beliefs

Behavioral and Brain Sciences ◽

10.1017/s0140525x18000274 ◽

2018 ◽

Vol 41 ◽

Author(s):

Kevin Arceneaux

Keyword(s):

Decision Making ◽

Individual Differences ◽

Cognitive Processes ◽

Evolutionary History ◽

Behavioral Responses ◽

History Of ◽

Economic Beliefs

AbstractIntuitions guide decision-making, and looking to the evolutionary history of humans illuminates why some behavioral responses are more intuitive than others. Yet a place remains for cognitive processes to second-guess intuitive responses – that is, to be reflective – and individual differences abound in automatic, intuitive processing as well.

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The role of affect in feelings of obligation

Behavioral and Brain Sciences ◽

10.1017/s0140525x19002449 ◽

2020 ◽

Vol 43 ◽

Author(s):

Stefen Beeler-Duden ◽

Meltem Yucel ◽

Amrisha Vaish

Keyword(s):

Positive Emotions ◽

The Creation ◽

Sense Of Obligation

Abstract Tomasello offers a compelling account of the emergence of humans’ sense of obligation. We suggest that more needs to be said about the role of affect in the creation of obligations. We also argue that positive emotions such as gratitude evolved to encourage individuals to fulfill cooperative obligations without the negative quality that Tomasello proposes is inherent in obligations.

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