An integrative proteomics metabolomics based strategy reveals the mechanisms involved in wasp sting induced acute kidney injury

Toxicon ◽  
2022 ◽  
Vol 205 ◽  
pp. 1-10
Author(s):  
Hai Yuan ◽  
Zhao Gao ◽  
Guang Chen ◽  
Changkun Peng ◽  
Yujun Sun ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Wasp Sting

scholarly journals Multiple Organ Dysfunction and Acute Pancreatitis Following Wasp Stings

2020 ◽  
Vol 18 (3) ◽  
pp. 566-568
Author(s):  
Olita Shilpakar ◽  
Bibek Rajbhandari ◽  
Bipin Karki ◽  
Umesh Bogati
Keyword(s):  
Acute Kidney Injury ◽  
Acute Pancreatitis ◽  
Organ Dysfunction ◽  
Kidney Injury ◽  
Complete Recovery ◽  
Multiple Organ ◽  
Multiple Organ Dysfunction ◽  
Wasp Sting ◽  
History Of ◽  
Wasp Stings

Wasp stings are common in our part of the world and may cause complications ranging from mild local reactions to fatal anaphylaxis. Severe cases may present with multisystem involvement causing acute kidney injury, hepatic dysfunction, clotting abnormalities, rhabdomyolysis or even death. However, cases with acute pancreatitis as a complication of wasp sting is not usual and have been very rarely reported. We present a case of a fifty-two-year-old lady with the history of multiple wasp stings followed by multiple organ dysfunction and acute pancreatitis with complete recovery following immediate conservative measures. Keywords: Acute kidney injury; multiple organ dysfunction; pancreatitis; wasp; sting

scholarly journals Peritoneal Dialysis in Children with Acute Kidney Injury: Dhaka Shishu (Children) Hospital Experience

2017 ◽  
Vol 6 (2) ◽  
pp. 11-14
Author(s):  
NK Sarker ◽  
M Hanif ◽  
MA Rouf ◽  
PK Sarkar ◽  
S Mahmud ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Developing Countries ◽  
Peritoneal Dialysis ◽  
Kidney Injury ◽  
Unknown Etiology ◽  
Cross Sectional ◽  
Wasp Sting ◽  
Medical College ◽  
Common Causes ◽  
Uremic Syndrome

Background: The choices for renal replacement therapy (RRT) in children with acute kidney injury (AKI) are limited in developing countries. Peritoneal dialysis (PD) is the preferred and convenient treatment modality for acute kidney injury (AKI) in children and hemodynamically unstable patients.Methods: This is a cross sectional descriptic type of observational study of children who underwent PD for AKI in 43 children (27 boys) in nephrology department of Dhaka Shishu (children) Hospital from January 2013 to December 2013.Result: The study included 43 children (62.8 % male). Mean age was 2 ± 1.07 years, with the youngest being 2 months, and the oldest, 14 years. Most common causes was septicaemia (25.6%) and hypovolumia (25.6%) followed by unknown etiology (16.2%), glomerulonephritis (11.6%), wasp sting (9.3%) and hemolytic uremic syndrome (7%). Overall mortality was 32.5%, most common in unknown etiology and high in male but not statistically significant (p=0.42).Conclusions: In the developing countries, PD can be successfully performed for the management of childhood AKI. Septicaemia and hypovolumia are the leading causes of AKI, however mortality higher in male and unknown etiology.Anwer Khan Modern Medical College Journal Vol. 6, No. 2: July 2015, P 11-14

Efficacy of Three Renal Replacement Therapy Modalities for the Treatment of Acute Kidney Injury Caused by Wasp Sting

2021 ◽  
pp. 1-11
Author(s):  
Fugang Li ◽  
Li Liu ◽  
Dezheng Chen ◽  
Yong Zhang ◽  
Mingli Wang ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Kidney Injury ◽  
Therapeutic Effects ◽  
Wasp Sting ◽  
Laboratory Results ◽  
Better Than

<b><i>Background/Aim:</i></b> This study mainly aimed to explore the therapeutic effects of 3 renal replacement therapy (RRT) modalities on acute kidney injury (AKI) caused by wasp stings. <b><i>Methods:</i></b> A retrospective study from September 2016 to December 2019 was conducted. Thirty-one patients with AKIs caused by wasp sting were selected and divided into 3 groups according to the initial RRT modality received, namely, (1) the intermittent hemodialysis combined with hemoperfusion (IHD + HP) group, (2) the continuous veno-venous hemodiafiltration (CVVHDF) group, and (3) the CVVHDF combined with HP (CVVHDF + HP) group. The laboratory results were measured and analyzed before treatment on the 3rd, 7th, and 14th days of treatment. The renal function outcomes and survival of the patients were investigated at 3 months follow-up. <b><i>Results:</i></b> The laboratory results of enzyme measures and inflammatory indicators in wasp sting patients increased significantly in the early stage and 3 RRT modalities were effective in reducing these indicators. In addition, continuous RRT modality (CVVHDF and CVVHDF + HP) showed better clearance of myoglobin than IHD + HP. The serum creatinine levels of patients in the 3 groups did not recover to baseline within 14 days after beginning treatment. Nevertheless, the CVVHDF + HP group was better than the CVVHDF group, and CVVHDF was better than the IHD + HP group on the 3rd day. The interleukin (IL)-6 and IL-10 levels in CVVHDF + HP and IHD + HP groups were obviously lower than those in the CVVHDF group on the 3rd day. In the follow-up study, the recovery rate of renal function in CVVHDF and CVVHDF + HP groups was significantly better than that in the IHD + HP group. <b><i>Conclusion:</i></b> Early RRT was effective in the treatment of patients with A KI caused by wasp sting. CVVHDF + HP and CVVHDF modalities were better than the IHD + HP group in venom clearance and renal function recovery.

scholarly journals Acute Pancreatitis and Rhabdomyolysis with Acute Kidney Injury following Multiple Wasp Stings

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Seo Hee Yang ◽  
Yeon Han Song ◽  
Tae Hoon Kim ◽  
Su Bin Kim ◽  
Sang Youb Han ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Acute Pancreatitis ◽  
Kidney Injury ◽  
Multiple Organ ◽  
Wasp Sting ◽  
Rare Manifestation ◽  
Liver And Pancreas ◽  
Wasp Stings ◽  
Kidney Liver ◽  
Toxic Reactions

Multiple wasp stings can induce multiple organ dysfunction by toxic reactions. However, acute pancreatitis is a rare manifestation in wasp sting injury. A 74-year-old woman visited the emergency department by anaphylactic shock because of multiple wasp stings. Acute kidney injury, rhabdomyolysis, hepatotoxicity, and coagulopathy were developed next day. Serum amylase and lipase were elevated and an abdominal computed tomography revealed an acute pancreatitis. Urine output was recovered after 16 days of oliguria (below 500 ml/day). Her kidney, liver, and pancreas injury gradually improved after sessions of renal replacement therapy.

scholarly journals Wasp sting-induced acute kidney injury

2016 ◽  
Vol 9 (2) ◽  
pp. 201-204 ◽  
Author(s):  
Jeyachandran Dhanapriya ◽  
Thanigachalam Dineshkumar ◽  
Ramanathan Sakthirajan ◽  
Palaniselvam Shankar ◽  
Natarajan Gopalakrishnan ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Wasp Sting

Acute Kidney Injury Following Wasp Stings - A Case Report and Literature Review

2018 ◽  
Vol 42 (2) ◽  
pp. 98-101
Author(s):  
Sayeeda Anwar ◽  
Nasir Hossain ◽  
Farzana Kabir Rozana ◽  
Sultan Mahamud Sumon
Keyword(s):  
Acute Kidney Injury ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Case Report ◽  
Kidney Injury ◽  
Wasp Sting ◽  
Renal Functions ◽  
Wasp Stings ◽  
Supportive Management ◽  
Fatal Complications

The manifestations of wasp stings are usually benign and localized at the site of stings but susceptible individuals may present with multisystem and potentially fatal complications like hemolytic anaemia, acute renal failure and shock. We report here a child who developed acute kidney injury seven days after multiple wasp stings. The renal functions recovered with supportive management including two sessions of peritoneal dialysis. This case report highlights that management of some of the wasp stings should be done in consultation with centre which has facilities for dialysis. The management of wasp sting should be started as early as possible and when progressive renal failure ensues, intensive dialysis support results in good renal recovery in majority of survivors.Bangladesh J Child Health 2018; VOL 42 (2) :98-101

scholarly journals Acute kidney injury in wasp sting-do early bicarbonate and mannitol make a difference?

2014 ◽  
Vol 18 (10) ◽  
pp. 701-702 ◽  
Author(s):  
Ponniah Thirumalaikolundusubramanian ◽  
Florence Benita ◽  
Chidambaram Ananth
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Wasp Sting

Acute Kidney Injury Due to Acute Cortical Necrosis Following a Single Wasp Sting

Renal Failure ◽  
2012 ◽  
Vol 35 (1) ◽  
pp. 170-172 ◽  
Author(s):  
Vivek Kumar ◽  
Ritambhra Nada ◽  
Sravan Kumar ◽  
Raja Ramachandran ◽  
Manish Rathi ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Cortical Necrosis ◽  
Wasp Sting
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