wasp sting
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Toxicon ◽  
2022 ◽  
Vol 205 ◽  
pp. 1-10
Author(s):  
Hai Yuan ◽  
Zhao Gao ◽  
Guang Chen ◽  
Changkun Peng ◽  
Yujun Sun ◽  
...  

2021 ◽  
pp. 1-11
Author(s):  
Fugang Li ◽  
Li Liu ◽  
Dezheng Chen ◽  
Yong Zhang ◽  
Mingli Wang ◽  
...  

<b><i>Background/Aim:</i></b> This study mainly aimed to explore the therapeutic effects of 3 renal replacement therapy (RRT) modalities on acute kidney injury (AKI) caused by wasp stings. <b><i>Methods:</i></b> A retrospective study from September 2016 to December 2019 was conducted. Thirty-one patients with AKIs caused by wasp sting were selected and divided into 3 groups according to the initial RRT modality received, namely, (1) the intermittent hemodialysis combined with hemoperfusion (IHD + HP) group, (2) the continuous veno-venous hemodiafiltration (CVVHDF) group, and (3) the CVVHDF combined with HP (CVVHDF + HP) group. The laboratory results were measured and analyzed before treatment on the 3rd, 7th, and 14th days of treatment. The renal function outcomes and survival of the patients were investigated at 3 months follow-up. <b><i>Results:</i></b> The laboratory results of enzyme measures and inflammatory indicators in wasp sting patients increased significantly in the early stage and 3 RRT modalities were effective in reducing these indicators. In addition, continuous RRT modality (CVVHDF and CVVHDF + HP) showed better clearance of myoglobin than IHD + HP. The serum creatinine levels of patients in the 3 groups did not recover to baseline within 14 days after beginning treatment. Nevertheless, the CVVHDF + HP group was better than the CVVHDF group, and CVVHDF was better than the IHD + HP group on the 3rd day. The interleukin (IL)-6 and IL-10 levels in CVVHDF + HP and IHD + HP groups were obviously lower than those in the CVVHDF group on the 3rd day. In the follow-up study, the recovery rate of renal function in CVVHDF and CVVHDF + HP groups was significantly better than that in the IHD + HP group. <b><i>Conclusion:</i></b> Early RRT was effective in the treatment of patients with A KI caused by wasp sting. CVVHDF + HP and CVVHDF modalities were better than the IHD + HP group in venom clearance and renal function recovery.


2021 ◽  
Author(s):  
Maohe Wang ◽  
Mei Qin ◽  
Amanda Y Wang ◽  
Jia Wei Zhao ◽  
Fei Deng ◽  
...  

Abstract Background We aimed to assess the utility of the poisoning severity score (PSS) as early prognostic predictors in patients with wasp stings, and to explore a reliable and simple predictive tool for short-term outcomes. Methods From January 2016 to December 2018, 363 patients with wasp stings in Suining Central Hospital were taken as research subjects. In the first 24h of hospital admission, the PSS and Chinese expert consensus on standardized diagnosis and treatment of wasp stings (CECC) were used as the criterion for severity classification, and their correlation was analyzed. The patients were divided into survival and death groups according to the state of discharge. The factors that affect outcome were analyzed by logistic regression analysis. A clinical prognostic model of death was constructed according to the risk factors, and 1000 times repeated sampling was done to include the data to verify the model internally. Results The mortality of wasp sting patients was 3.9%. There was a correlation between PSS and CECC (r=0.435, P<0.001) for severity classification. Sex, age, number of stings, and PSS were independent risk factors for death. Based on the 4 independent risk factors screened by the above regression analysis, a nomogram model was constructed to predict the risk of death in wasp sting patients. The predicted value C-index was 0.962, and the internally verified AUC was 0.962(95%C.I. 0.936-0.988, P<0.001). Conclusions PSS is helpful in the early classification of the severity of wasp stings. Sex, age, number of stings, and PSS were independent risk factors for death in wasp sting patients. The nomogram model established in this study can accurately predict the occurrence of the risk of death.


2021 ◽  
Author(s):  
Yong Liu ◽  
Hongmei Shu ◽  
Youlin Long ◽  
Xiaoqin Nie ◽  
Hongfu Tang ◽  
...  

Abstract Background In recent years, the incidence of wasp sting has increased annually in China. Organ damage and high mortality due to mass wasp envenomation remain major challenges. Timely and appropriate medical intervention can improve survival. However, there are currently no normalized tools for early assessment of severity. Methods The clinical data of wasp sting patients hospitalized from 2011 to 2019 were used as a training set. Logistic regression was used to explore major risk factors for the development of a severe case of wasp stings (SC). The Wasp Sting Severity Score (WSS) was determined considering these risk factors to identify SCs and was tested in a validation dataset that was prospectively collected in 2020. Results The data of 1131 wasp sting patients from 2011–2019 were included in the training set. Logistic regression analysis showed that tea-colored urine (TCU), number of stings, and lactate dehydrogenase (LDH) and total bilirubin (TBIL) levels were risk factors for developing a SC. The WSS was developed considering these four risk factors, and the total possible WSS was 20 points. The WSS was tested using the validation dataset, comprising the data of 153 patients, in 2020, and we found that a WSS ≥3 points was an important indication for blood purification, with a sensitivity of 71.9%, specificity of 92.6% and an area under the curve (AUC) of 0.918 (95% CI 0.873–0.962). Among patients with more than 30 stings, mortality in those who underwent plasma exchange (PE) within 24 hours after admission was significantly lower than that in those who did not receive PE treatment (14.3% vs. 46.9%, P = 0.003). However, continuous venovenous hemofiltration (CVVH) (P = 0.317) and hemoperfusion (HP) (P = 0.869) did not significantly reduce mortality. Conclusions Patients with WSS scores ≥ 3 should be considered for blood purification as early as possible in addition to routine treatment. In addition, PE is better than CVVH and HP at reducing mortality in patients suffering from severe wasp stings.


2021 ◽  
Author(s):  
Maohe Wang ◽  
Mei Qin ◽  
Amanda Y Wang ◽  
Jia Wei Zhao ◽  
Fei Deng ◽  
...  

Abstract Background: We aimed to assess the utility of the poisoning severity score (PSS) as early prognostic predictors in patients with wasp stings, and to explore a reliable and simple predictive tool for short-term outcomes.Methods: From January 2016 to December 2018, 363 patients with wasp stings in Suining Central Hospital were taken as research subjects. In the first 24h of hospital admission, the PSS and Chinese expert consensus on standardized diagnosis and treatment of wasp stings (CECC) were used as the criterion for severity classification, and their correlation was analyzed. The patients were divided into survival and death groups according to the state of discharge. The factors that affect outcome were analyzed by logistic regression analysis. A clinical prognostic model of death was constructed according to the risk factors, and 1000 times repeated sampling was done to include the data to verify the model internally.Results: The mortality of wasp sting patients was 3.9%. There was a correlation between PSS and CECC (r=0.435, P<0.001) for severity classification. Sex, age, number of stings, and PSS were independent risk factors for death. Based on the 4 independent risk factors screened by the above regression analysis, a nomogram model was constructed to predict the risk of death in wasp sting patients. The predicted value C-index was 0.962, and the internally verified AUC was 0.962(95%C.I. 0.936-0.988, P<0.001).Conclusions: PSS is helpful in the early classification of the severity of wasp stings. Sex, age, number of stings, and PSS were independent risk factors for death in wasp sting patients. The nomogram model established in this study can accurately predict the occurrence of the risk of death.


Author(s):  
Renato Erzen ◽  
Ana Koren ◽  
Julij Selb ◽  
Nissera Bajrovic ◽  
Nika Lalek ◽  
...  
Keyword(s):  

2021 ◽  
pp. practneurol-2021-003007
Author(s):  
Boby Varkey Maramattom

A 48-year-old man presented with a headache and disorientation after multiple wasp stings. Following admission, he developed seizures and was intubated. We provisionally diagnosed wasp sting-related allergic encephalitis and treated this with intravenous methylprednisolone and intravenous immunoglobulin. He recovered uneventfully over several days.


2021 ◽  
Vol p5 (03) ◽  
pp. 2768-2774
Author(s):  
Vijitha Vijayan

Wasp stings are common especially during the warmer months when people are outside for longer periods of time. They are equipped with a stinger for self-defence. A wasp’s stinger contains venom that is transmitted to humans during a sting. Local manifestations following stings are common and usually life-threatening anaphylax- is may occur. Most of the cases involve one or a few stings where only local symptoms without any serious aller- gic reactions. In such cases Vishaghna lepas (antitoxic topical applications) can be used as it nullifies the harmful or poisonous effects along with medicinal intake. Here, in this study, the efficacy of Kushmandabeejadi lepa churna, mentioned in Kriyakoumudi (traditional book on toxicology) for wasp sting is studied by administering it along with another widely practiced classical preparation. Aim and Objectives- The study was conducted to study the efficacy of Kushmandabeejadi lepa against Sigrupunarnavadi lepa along with Dasanga agada in the management of Wasp sting Methods- A clinical study with 20 participants fulfilling the diagnostic and inclusion criteria was selected alternately and assigned in to two groups. Group 1(trial group) received Kushmanadabeejadi lepa Churna and Group 2(control group) received Sigrupunarnavadi lepa churna five times daily for a period of three days, both as external application. Fourth day was observatory period and assessment was done on fifth day. In both groups, Dasanga Agada was used as common internal medicine. Results-The outcome variables – pain, itching, erythema and swelling were assessed for the change in mean score values. Data were analysed statistical- ly using Mann-Whitney U Test and Wilcoxon Signed Rank Test. The result obtained was significant in relieving the cardinal symptoms of wasp sting Conclusion- The overall effect shows that both the treatments individually were significant in the management of wasp sting and Kushmandabeejadi lepa is equally effective in managing the signs and symptoms produced by wasp sting when compared with Sigrupunarnavadi lepa. Keywords: Kushmandabeejadi Lepa; wasp sting; Sigrupunarnavadi Lepa; Vishaghna Lepa, Dasanga agada


2021 ◽  
Vol 09 (3) ◽  
pp. 529-535
Author(s):  
Vijitha Vijayan

Wasp stings are common especially during the warmer months when people are outside for longer periods of time. They are equipped with a stinger for self-defence. A wasp’s stinger contains venom that is trans-mitted to humans during a sting. Local manifestations following stings are common and usually life-threatening anaphylaxis may occur. Most of the cases involve one or a few stings where only local symp-toms without any serious allergic reactions. In such cases Vishaghna lepas (antitoxic topical applications) can be used as it nullifies the harmful or poisonous effects along with medicinal intake. Here, in this study, the efficacy of Kushmandabeejadi lepa churna, mentioned in Kriyakoumudi (traditional book on toxicolo-gy) for wasp sting is studied by administering it along with another widely practiced classical preparation. Aim and Objectives- The study was conducted to study the efficacy of Kushmandabeejadi lepa against Sigrupunarnavadi lepa along with Dasanga agada in the management of Wasp sting Methods- A clinical study with 20 participants fulfilling the diagnostic and inclusion criteria was selected alternately and as-signed in to two groups. Group 1(trial group) received Kushmanadabeejadi lepa churna and Group 2(control group) received Sigrupunarnavadi lepa churna five times daily for a period of three days, both as external application. Fourth day was observatory period and assessment was done on fifth day. In both groups, Dasanga agada was used as common internal medicine. Results-The outcome variables – pain, itching, erythema and swelling were assessed for the change in mean score values. Data were analysed sta-tistically using Mann-Whitney U Test and Wilcoxon Signed Rank Test. The result obtained was significant in relieving the cardinal symptoms of wasp sting Conclusion- The overall effect shows that both the treat-ments individually were significant in the management of wasp sting and Kushmandabeejadi lepa is equal-ly effective in managing the signs and symptoms produced by wasp sting when compared with Sigru-punarnavadi lepa.


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