Glutathione cycle induction against sulfur mustard cytotoxicity on human skin fibroblast cell line (HF2FF)

2008 ◽  
Vol 180 ◽  
pp. S115
Author(s):  
Mehdi Saberi ◽  
Ali Zaree ◽  
Ali Khoshbaten
Keyword(s):  
Cell Line ◽  
Human Skin ◽  
Skin Fibroblast ◽  
Sulfur Mustard ◽  
Fibroblast Cell ◽  
Human Skin Fibroblast ◽  
Fibroblast Cell Line ◽  
Glutathione Cycle ◽  
Human Skin Fibroblast Cell

scholarly journals Effect of enoxaparin and onion extract on human skin fibroblast cell line – Therapeutic implications for the treatment of keloids

2013 ◽  
Vol 52 (2) ◽  
pp. 262-267 ◽  
Author(s):  
Michał Pikuła ◽  
Maria E. Żebrowska ◽  
Loretta Pobłocka-Olech ◽  
Mirosława Krauze-Baranowska ◽  
Małgorzata Sznitowska ◽  
...  
Keyword(s):  
Cell Line ◽  
Human Skin ◽  
Skin Fibroblast ◽  
Fibroblast Cell ◽  
Human Skin Fibroblast ◽  
Fibroblast Cell Line ◽  
Therapeutic Implications ◽  
Onion Extract ◽  
Human Skin Fibroblast Cell

ЦИТОТОКСИЧЕСКОЕ ДЕЙСТВИЕ ПОЛИАКРИЛАТА ЗОЛОТА (АУРУМАКРИЛ) НА ФИБРОБЛАСТЫ КОЖИ ЧЕЛОВЕКА

2020 ◽  
Vol 65 (6) ◽  
pp. 1093-1098
Author(s):  
Д.Б. Корман ◽  
◽  
Е.И. Некрасова ◽  
Л.А. Островская ◽  
О.О. Рябая ◽  
...  
Keyword(s):  
Human Skin ◽  
Skin Fibroblast ◽  
Cytotoxic Effect ◽  
Inhibitory Concentration ◽  
Fibroblast Cell ◽  
Human Skin Fibroblast ◽  
Fibroblast Cell Line ◽  
Human Skin Fibroblast Cell ◽  
Potential Antitumor

The cytotoxic effect of the potential antitumor drug aurumacryl (aurum polyacrylate) on the hFB-hTERT6 human skin fibroblast cell line has been studied in vitro. It has been established that aurumacril exhibits substantial cytotoxicity to human skin fibroblasts. The maximum of cytotoxic effect (75% cell death) was observed when the concentration of aurumacryl was 0.125 mg/ml. The inhibitory concentration of aurumacryl causing 50% human skin fibroblast death (IC50) was 0.09 mg/ml.

scholarly journals Niosome Encapsulated Bromelain Reduced IL-6 and TNF-α in LPS Induced Human Skin Fibroblast Cell Line

2021 ◽  
Vol 2 (7) ◽  
pp. 01-10
Author(s):  
Siavash Hosseinpour Chermahini ◽  
Fadzilah Adibah Abdul Majid ◽  
Azila Abdul Aziz ◽  
Roya Anvari
Keyword(s):  
Cell Line ◽  
Human Skin ◽  
Skin Fibroblast ◽  
Skin Barrier ◽  
Fibroblast Cell ◽  
Skin Inflammation ◽  
Human Skin Fibroblast ◽  
Necrosis Factor Alpha ◽  
Tnf Α

The topical delivery of bromelain as an anti-inflammatory solution for skin inflammation has attracted the attention of researchers. Due to the skin barrier issue, a new method was designed for the effective delivery of specific doses of bromelain to the desired action sites. A niosome was selected as a novel and practical transdermal vehicle for the delivery of bromelain to inflamed sites. In this regard, a lipopolysaccharide (LPS)-induced human skin fibroblast (HSF1184) cell line was assembled in-vitro as a simulated model. The levels of interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-α), the two immune-modulatory regulators of cell responses to inflammation, were measured to determine the response towards the niosome-encapsulated bromelain treatment. The results showed that the niosome-encapsulated bromelain significantly reduced the levels of IL-6 and TNF-α compared to the non-encapsulated bromelain, the vehicle (niosome) and the control.

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