scholarly journals Inhibitory effect of Camellia sinensis , Ilex paraguariensis and Ardisia compressa tea extracts on the proliferation of human head and neck squamous carcinoma cells

2016 ◽  
Vol 3 ◽  
pp. 269-278 ◽  
Author(s):  
Marco Vinicio Ramirez-Mares ◽  
Hideka Kobayashi ◽  
Elvira Gonzalez de Mejia
Keyword(s):  
Head And Neck ◽  
Camellia Sinensis ◽  
Squamous Carcinoma ◽  
Human Head ◽  
Inhibitory Effect ◽  
Carcinoma Cells ◽  
Ilex Paraguariensis ◽  
Squamous Carcinoma Cells

Reovirus oncolysis in human head and neck squamous carcinoma cells

2004 ◽  
Vol 31 (4) ◽  
pp. 407-412 ◽  
Author(s):  
Y IKEDA ◽  
G NISHIMURA ◽  
S YANOMA ◽  
A KUBOTA ◽  
M FURUKAWA ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Carcinoma ◽  
Human Head ◽  
Carcinoma Cells ◽  
Squamous Carcinoma Cells

Midazolam inhibits the proliferation of human head and neck squamous carcinoma cells by downregulating p300 expression

Tumor Biology ◽  
2014 ◽  
Vol 35 (8) ◽  
pp. 7499-7504 ◽  
Author(s):  
Yun-ling Dou ◽  
Jia-ping Lin ◽  
Feng-en Liu ◽  
Ling-yan Wang ◽  
Hai-hua Shu ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Carcinoma ◽  
Human Head ◽  
Carcinoma Cells ◽  
Squamous Carcinoma Cells

scholarly journals Mitoferrin-2-dependent Mitochondrial Iron Uptake Sensitizes Human Head and Neck Squamous Carcinoma Cells to Photodynamic Therapy

2012 ◽  
Vol 288 (1) ◽  
pp. 677-686 ◽  
Author(s):  
Hsin-I Hung ◽  
Justin M. Schwartz ◽  
Eduardo N. Maldonado ◽  
John J. Lemasters ◽  
Anna-Liisa Nieminen
Keyword(s):  
Photodynamic Therapy ◽  
Head And Neck ◽  
Iron Uptake ◽  
Squamous Carcinoma ◽  
Human Head ◽  
Carcinoma Cells ◽  
Squamous Carcinoma Cells ◽  
Mitochondrial Iron

scholarly journals Induction of Cell Cycle Arrest and Apoptotic Response of Head and Neck Squamous Carcinoma Cells (Detroit 562) by Caffeic Acid and Caffeic Acid Phenethyl Ester Derivative

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Arkadiusz Dziedzic ◽  
Robert Kubina ◽  
Agata Kabała-Dzik ◽  
Marta Tanasiewicz
Keyword(s):  
Cell Cycle ◽  
Phenolic Compounds ◽  
Head And Neck ◽  
Caffeic Acid ◽  
Squamous Carcinoma ◽  
Human Head ◽  
Caffeic Acid Phenethyl Ester ◽  
Carcinoma Cells ◽  
Dead Cell ◽  
Squamous Carcinoma Cells

Natural polyphenols have been observed to possess antiproliferative properties. The effects, including apoptotic potential of bioactive phenolic compounds, caffeic acid (CA) and its derivative caffeic acid phenethyl ester (CAPE), on cell proliferation and apoptosis in human head and neck squamous carcinoma cells (HNSCC) line (Detroit 562) were investigated and compared. Cancer cells apoptosis rates and cell cycle arrests were analysed by flow cytometry. Exposure to CA and CAPE was found to result in a dose-dependent decrease in the viability of Detroit 562 cells at different levels. CA/CAPE treatment did significantly affect the viability of Detroit 562 cells (MTT results). CAPE-mediated loss of viability occurred at lower doses and was more pronounced, with the concentrations which inhibit the growth of cells by 50% estimated at 201.43 μM (CA) and 83.25 μM (CAPE). Dead Cell Assay with Annexin V labelling demonstrated that CA and CAPE treatment of Detroit 562 cells resulted in an induction of apoptosis at 50 μM and 100 μM doses. The rise of mainly late apoptosis was observed for 100 μM dose and CA/CAPE treatment did affect the distribution of cells in G0/G1 phase. A combination of different phenolic compounds, potentially with chemotherapeutics, could be considered as an anticancer drug.

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