The hybridization chain reaction in the development of ultrasensitive nucleic acid assays

2015 ◽  
Vol 64 ◽  
pp. 86-99 ◽  
Author(s):  
Juleiha Ikbal ◽  
Geraldine S. Lim ◽  
Zhiqiang Gao
Keyword(s):  
Nucleic Acid ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Nucleic Acid Assays

Silver nanocluster-lightened hybridization chain reaction

RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57502-57506 ◽  
Author(s):  
Lin Liu ◽  
Qing Li ◽  
Li-Juan Tang ◽  
Ru-Qin Yu ◽  
Jian-Hui Jiang
Keyword(s):  
Nucleic Acid ◽  
Silver Nanoclusters ◽  
Hybridization Chain Reaction ◽  
Label Free ◽  
Chain Reaction ◽  
Silver Nanocluster ◽  
Turn On ◽  
Nucleic Acid Assays

A hybridization chain reaction (HCR) lightened by DNA-stabilized silver nanoclusters (AgNCs) as a label-free and turn on fluorescence platform for nucleic acid assays.

Traditional and new applications of HCR in biosensing and biomedicine

The Analyst ◽  
2021 ◽  
Author(s):  
Rong Zhou ◽  
Zhuoer Zeng ◽  
Ruowei Sun ◽  
Wenfang Liu ◽  
Qubo Zhu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Double Helix ◽  
Nucleic Acid Amplification ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Single Stranded Dna ◽  
Isothermal Nucleic Acid Amplification ◽  
Hybridization Event ◽  
Nucleic Acid Amplification Technology ◽  
New Applications

Hybridization chain reaction is a very popular isothermal nucleic acid amplification technology. A single-stranded DNA initiator triggers an alternate hybridization event between two hairpins forming a double helix polymer. Due...

Framework Nucleic Acid-Mediated Pull-Down MicroRNA Detection with Hybridization Chain Reaction Amplification

2018 ◽  
Vol 1 (3) ◽  
pp. 859-864 ◽  
Author(s):  
Xiangmeng Qu ◽  
Mingshu Xiao ◽  
Fan Li ◽  
Wei Lai ◽  
Li Li ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Microrna Detection ◽  
Reaction Amplification

scholarly journals Three-dimensional DNA nanostructures to improve the hyperbranched hybridization chain reaction

2019 ◽  
Vol 10 (42) ◽  
pp. 9758-9767 ◽  
Author(s):  
Jing Wang ◽  
Dong-Xia Wang ◽  
Jia-Yi Ma ◽  
Ya-Xin Wang ◽  
De-Ming Kong
Keyword(s):  
Nucleic Acid ◽  
Three Dimensional ◽  
Nucleic Acid Amplification ◽  
Hybridization Chain Reaction ◽  
Dna Nanostructures ◽  
Chain Reaction ◽  
Nucleic Acid Amplification Techniques ◽  
Detection Of Biomarkers

Nonenzymatic nucleic acid amplification techniques (e.g. the hybridization chain reaction, HCR) have shown promising potential for amplified detection of biomarkers.

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