Pro-inflammatory cytokine profile of critically ill septic patients following therapeutic plasma exchange

2013 ◽  
Vol 48 (1) ◽  
pp. 75-78 ◽  
Author(s):  
Hadi Hamishehkar ◽  
Mohammad Taghi Beigmohammadi ◽  
Mohammad Abdollahi ◽  
Sarah Mousavi ◽  
Shadi Ziaie ◽  
...  
Keyword(s):  
Plasma Exchange ◽  
Critically Ill ◽  
Inflammatory Cytokine ◽  
Cytokine Profile ◽  
Therapeutic Plasma Exchange

scholarly journals Therapeutic plasma exchange in adult critically ill patients with life-threatening SARS-CoV-2 disease: A pilot study

2020 ◽  
Vol 60 ◽  
pp. 328-333 ◽  
Author(s):  
Fahad Faqihi ◽  
Abdulrahman Alharthy ◽  
Mohammed Alodat ◽  
Demetrios J. Kutsogiannis ◽  
Peter G. Brindley ◽  
...  
Keyword(s):  
Pilot Study ◽  
Plasma Exchange ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Therapeutic Plasma Exchange ◽  
Life Threatening

Therapeutic Plasma Exchange in Critically Ill Children Requiring Intensive Care

2018 ◽  
Vol 19 (2) ◽  
pp. e97-e104 ◽  
Author(s):  
Gerard Cortina ◽  
Rosemary McRae ◽  
Roberto Chiletti ◽  
Warwick Butt
Keyword(s):  
Intensive Care ◽  
Plasma Exchange ◽  
Critically Ill ◽  
Therapeutic Plasma Exchange ◽  
Critically Ill Children

scholarly journals Therapeutic Plasma Exchange: A potential Management Strategy for Critically Ill COVID-19 Patients

2020 ◽  
Vol 35 (9) ◽  
pp. 827-835 ◽  
Author(s):  
Seena Tabibi ◽  
Tara Tabibi ◽  
Rosalynn R. Z. Conic ◽  
Nassim Banisaeed ◽  
Michael B. Streiff
Keyword(s):  
Plasma Exchange ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Laboratory Data ◽  
Therapeutic Plasma Exchange ◽  
Medical Treatments ◽  
Clinical Observations ◽  
Cytokine Levels ◽  
Potential Benefits ◽  
Trial Phase

In the 5 months since initial reports of COVID-19 came to light, the death toll due to SARS-CoV-2 has rapidly increased. The morbidity and mortality of the infection varies based upon patient age, comorbid conditions, viral load, and the availability of effective treatments. Findings from limited autopsies, clinical observations, and laboratory data suggest that high cytokine levels and a procoagulant state can precipitate acute respiratory distress syndrome and multi-organ dysfunction syndrome in critically ill patients. To complicate matters, comorbidities may affect the response to medical treatments currently in use, all of which are still in trial phase. Therapeutic plasma exchange (TPE) merits consideration in the treatment of critically ill COVID-19 patients and is an avenue for clinical trials to pursue. If efficacious, faster recovery of patients may lead to shorter intensive care unit stays and less time on mechanical ventilation. Herein, we briefly discuss some of the various approaches currently being investigated for the treatment of SARS-CoV-2 with a focus on potential benefits of TPE for selected critically ill patients.

Sign in / Sign up

Export Citation Format

Share Document