Restoration of Endocrine Function and Ovulation After a Heterotopic Ovarian Transplant in the Inguinal Region of Rabbits Using a Vascular Microsurgical Technique

Abstract. Background: Effectiveness of vascular closure devices during endovascular procedures requiring a direct puncture of a vascular prosthesis placed in the inguinal region is unknown. Patients and methods: The retrospective analysis included 134 patients with a history of polyethylene terephthalate (PETE) graft implantation in the inguinal region. In 20 (15 %) patients, haemostasis was achieved with manual compression, in 21 (16 %) with the StarClose™, and in 93 (69 %) with the AngioSeal™ device. Results: The incidence of vascular complications in the manual compression group was higher (at a threshold of statistical significance) than in the device closure group (45.0 vs. 24.5 %, p = 0.059). The difference was considered statistically significant when manual compression was compared with the AngioSeal™ closure group (45.0 vs. 13.9 %, p < 0.01). The vascular complication rate in the StarClose™ group was significantly higher than in the AngioSeal™ group (71.4 vs. 13.9 %, p < 0.000001). While haematomas were the only vascular complications observed after application of AngioSeal™, both haematomas and pseudoaneurysms were found in the StarClose™ group. Conclusions: The AngioSeal™ vascular closure device provides better local haemostasis than the StarClose™ device or manual compression during endovascular interventions requiring a direct puncture of PETE grafts

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Endoscopic-Assisted Microsurgical Technique for Management of Anterior Cranial Fossa Lesions Using the Keyhole Supraorbital Approach

Journal of Neurological Surgery Part B Skull Base ◽

10.1055/s-0034-1383981 ◽

2014 ◽

Vol 75 (S 02) ◽

Author(s):

Ali Ayyad

Keyword(s):

Anterior Cranial Fossa ◽

Microsurgical Technique ◽

Supraorbital Approach ◽

Cranial Fossa

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Pediatric Replantation after Traumatic Amputation at the Distal Forearm: Rehabilitation Protocol and Outcomes

Journal of Hand and Microsurgery ◽

10.1055/s-0040-1703096 ◽

2020 ◽

Author(s):

Nicholas C. Oleck ◽

Radhika Malhotra ◽

Haripriya S. Ayyala ◽

Ramazi O. Datiashvili

Keyword(s):

Operating Room ◽

Multidisciplinary Team ◽

Distal Forearm ◽

Left Forearm ◽

Traumatic Amputation ◽

Postoperative Rehabilitation ◽

Rehabilitation Protocol ◽

Microsurgical Technique ◽

Optimal Function ◽

And Function

AbstractMajor limb replantation is a formidable task, especially in the pediatric setting. While meticulous microsurgical technique is required in the operating room, the authors aim to highlight the importance of postoperative rehabilitation therapy for optimal function. We highlight the case of a 12-year-old boy who suffered complete traumatic amputation through the distal left forearm. The limb was successfully replanted with successful restoration of sensation and function with the aid of intensive postoperative occupational therapy. A multidisciplinary team is of paramount importance to maximize function of a replanted upper extremity.

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METABOLIC AND ENDOCRINE ASPECTS OF THE WHIRLER MUTATION IN MALE MICE

Acta Endocrinologica ◽

10.1530/acta.0.0640347 ◽

1970 ◽

Vol 64 (2) ◽

pp. 347-358

Author(s):

A. Stanley Weltman ◽

Arthur M. Sackler

Keyword(s):

Locomotor Activity ◽

Endocrine Function ◽

Metabolic Rates ◽

Heterozygous Female ◽

Endocrine Organ ◽

General Body ◽

Adrenocortical Activity ◽

Body Weights ◽

Seminal Vesicle Weight ◽

Eosinophil Counts

ABSTRACT Body weight, metabolic rate, locomotor activity and alterations in endocrine organ activity were noted in recessive homozygous male whirler mice and the phenotypically »normal« heterozygotes. Representative populations of the two types were studied at different age levels. In general, body weights of the whirler mice were consistently and significantly lower. Open-field locomotion studies similarly indicated heightened locomotor activity. Total leukocyte and eosinophil counts were either markedly or significantly lower in the homozygous vs. heterozygous whirler groups. Evaluation of relative organ weights showed significantly increased adrenal weights in whirler mice sacrificed at 14 weeks and 11 months of age. These changes were accompanied by involution of the thymus. Thus, the varied data indicate persistent increased metabolism and adrenocortical activity during the life-span of the whirler mice. Seminal vesicle weight decreases in the whirler males at 11 months suggest lower gonadal function. The findings are in accord with previous studies of alterations in metabolic rates and endocrine function of homozygous whirler vs. heterozygous female mice.

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THE INFLUENCE OF 17α-METHYL-19-NORTESTOSTERONE ON THE ENDOCRINE FUNCTION OF THE ADRENAL CORTEX

Acta Endocrinologica ◽

10.1530/acta.0.xxxiii0388 ◽

1960 ◽

Vol XXXIII (III) ◽

pp. 388-400 ◽

Cited By ~ 6

Author(s):

L. G. Huis in 't Veld ◽

B. Louwerens ◽

P. A. F. van der Spek

Keyword(s):

Urinary Excretion ◽

Adrenal Cortex ◽

Direct Effect ◽

Chorionic Gonadotrophin ◽

Endocrine Function ◽

List Type ◽

Prolonged Administration ◽

Acth Secretion ◽

Male Patients ◽

Normal Males

ABSTRACT In two male patients and two castrated males, the influence of corticotrophin (ACTH) on the urinary excretion of neutral 17-ketosteroids and 17-hydroxycorticosteroids was determined before and during a period in which patients were treated with 5 mg 17α-methyl-19-nortestosterone (MNT) daily. In two castrated males, moreover, the influence of chorionic gonadotrophin and ACTH + chorionic gonadotrophin on the urinary excretion of 17-ketosteroids and 17-hydroxycorticosteroids was determined before and during a period of treatment with 5 mg MNT daily. Prolonged administration of MNT causes a decrease in the urinary excretion of neutral 17-ketosteroids and 17-hydroxycorticosteroids both in the normal males and in the male castrates. ACTH caused an increase in the urinary excretion of 17-ketosteroids and 17-hydroxycorticosteroids before and during MNT administration. During MNT administration this increase (expressed in mg/24 hours) was ≤ the increase produced by the same dose of ACTH prior to MNT administration. In two male castrates treated with MNT, chorionic gonadotrophin caused no increase in the urinary excretion of 17-ketosteroids and 17-hydroxycorticosteroids. The effect obtained before and during MNT administration by administration of ACTH + chorionic gonadotrophin did not exceed the effect obtained by the same dose of ACTH alone. Our conclusion is that the effect of MNT on the excretion of adrenocortical steroids is not due to the inhibition of the ACTH secretion. The possibility of a direct effect of MNT on the adrenal cortex has not been excluded with complete certainty. A change in the corticosteroid metabolism due to the influence of MNT, however, must also be taken into consideration.

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