Adaptive Support Ventilation Versus Synchronized Intermittent Mandatory Ventilation With Pressure Support in Weaning Patients After Orthotopic Liver Transplantation

Purpose. The aim of this study was to compare the metabolic load between adaptive support ventilation (ASV) and pressure support ventilation (PSV) modes in critically ill patients. Methods. Sequential 20 min ventilation by PSV followed by 20 min ASV in critically ill patients was assessed. ASV was set for full support, i.e., with the minute volume control set at the same level as the minute volume observed during PSV. The trial started from PSV 8 cmH2O and continued with high (PSV 12 cmH2O) to low (PSV 0) conditions or low to high conditions, in random order. The oxygen consumption (VO2), production of carbon dioxide (VCO2), and energy expenditure (EE) were measured by indirect calorimetry (IC). Results. Twenty-four patients with critical illness participated in the study. Comparing with the PSV mode, the EE in the ASV mode was lower in the level of PSV 0 cmH2O (1069 ± 73 vs. 1425 ± 76 kcal), PS 8 cmH2O (1116 ± 70 vs. 1284 ± 61 kcal), and PS 12 cmH2O (1017 ± 70 vs. 1169 ± 58 kcal) (p<0.05). The VO2, VCO2, and P0.1 in PSV were significantly higher than those in ASV (p<0.05). Conclusion. In patients with critical illness, the application of ASV set for full support was associated with a lower metabolic load and respiratory drive than in any of the studied PSV conditions.

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Effects of Adaptive Support Ventilation and Synchronized Intermittent Mandatory Ventilation on Peripheral Circulation and Blood Gas Markers of COPD Patients with Respiratory Failure

Cell Biochemistry and Biophysics ◽

10.1007/s12013-014-9944-1 ◽

2014 ◽

Vol 70 (1) ◽

pp. 481-484 ◽

Cited By ~ 3

Author(s):

Ling Han ◽

Yingxiao Wang ◽

Yonghua Gan ◽

Lijun Xu

Keyword(s):

Respiratory Failure ◽

Peripheral Circulation ◽

Blood Gas ◽

Intermittent Mandatory Ventilation ◽

Adaptive Support Ventilation ◽

Support Ventilation ◽

Copd Patients ◽

Adaptive Support

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Application Of Adaptive Support Ventilation In Korean Patients With Acute Lung Injury

10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3008 ◽

2010 ◽

Author(s):

Wou Young Chung ◽

Keu Sung Lee ◽

Joo Hun Park ◽

Seung Soo Sheen ◽

Sung Chul Hwang ◽

...

Keyword(s):

Acute Lung Injury ◽

Lung Injury ◽

Adaptive Support Ventilation ◽

Support Ventilation ◽

Korean Patients ◽

Adaptive Support

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Adaptive Support Ventilation as a Sole Mode of Mechanical Ventilation-An Observational Study

Birat Journal of Health Sciences ◽

10.3126/bjhs.v1i1.17090 ◽

2017 ◽

Vol 1 (1) ◽

pp. 8-12

Author(s):

L.K. Rajbanshi ◽

M. Dali ◽

S.B. Karki ◽

K. Khanal ◽

B. Aryal ◽

...

Keyword(s):

Intensive Care Unit ◽

Mechanical Ventilation ◽

Intensive Care ◽

Observational Study ◽

Ventilatory Support ◽

Control Mode ◽

Adaptive Support Ventilation ◽

Support Ventilation ◽

Adaptive Support ◽

The Mean

Introduction Adaptive support ventilation (ASV) is a close loop dual control mechanical ventilation mode. This mode can automatically change its parameters to weaning mode once the patient is actively breathing converting volume targeted pressure control mode to volume targeted pressure support mode. We aimed to observe the outcome of the patients ventilated with ASV as a sole mode in terms of duration of mechanical ventilation, duration of weaning from the ventilatory support and length of Intensive care unit (ICU) stay.Methodology We conducted a prospective observational study for the duration of six months (Sept 2015 to Feb 2016) to assess the clinical outcome of the patients ventilated by ASV as a sole mode of ventilation. The study conducted observation of 78 patients without chronic respiratory, renal, hepatic and neurological disease who were admitted in our intensive care unit for invasive ventilatory support.Results Out of the 187 patients who required invasive and noninvasive ventilation, only 78 patients fulfilled the criteria to be included in the study. It was observed that the mean duration of mechanical ventilation was 5.4 days while weaning as well as tracheal extubation was successful within 13 hours of initiation of weaning. The mean duration of ICU stay was found to be 6.3 days.Conclusion We concluded that the patient ventilated by ASV mode were effectively weaned without the need of changing the ventilator mode. However, the safety of ASV mode needs to be established by large randomized control trail in a wide spectrum of patients.Birat Journal of Health Sciences 2016 1(1): 8-12

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