scholarly journals Liver Transplantation Reverses Hepatic Myelopathy in Hepatitis B-Related Decompensated Liver Cirrhosis: Case Report and Review of the Literature

Author(s):  
Zebin Zhu ◽  
Yang Liu ◽  
Wei Wu ◽  
Dehao Huang ◽  
Yafei Guo ◽  
...  
BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chi Hyuk Oh ◽  
Jin San Lee

Abstract Background Cerebral microbleeds (CMBs) are small, rounded, dark-signal lesions on brain MRI that represent cerebral hemosiderin deposits resulting from prior microhemorrhages and are neuroimaging biomarkers of cerebral amyloid angiopathy (CAA). Here, we report a case of innumerable CMBs in a patient with hepatic encephalopathy underlying decompensated liver cirrhosis. Case presentation An 83-year-old woman diagnosed with hepatitis B virus-related liver cirrhosis 40 years before was referred to our neurology clinic for progressive disorientation of time and place, personality changes, and confusion with somnolence over 2 weeks. Based on the laboratory, neuroimaging, and electrophysiological findings, we diagnosed the patient with hepatic encephalopathy, and her symptoms recovered within 12 h after proper medical management. Brain MRI showed innumerable CMBs in the bilateral frontal, parietal, temporal, and occipital lobes. Since the distribution of CMBs in the patient was mainly corticosubcortical and predominantly in the posterior cortical regions, and the apolipoprotein E genotype was ε4/ε4, we speculated that CAA and hepatic encephalopathy coexisted in this patient. Conclusions We suggest that severe liver dysfunction associated with long-term decompensated liver cirrhosis may be related to an increased number of CMBs in the brain. Our findings indicate that decompensated liver cirrhosis may be a risk factor for the development of CMBs and corroborate a link between the liver and the brain.


2020 ◽  
Vol 7 (07) ◽  
pp. 4871-4874
Author(s):  
Amal Hajri ◽  
Abdessamad El Azhary ◽  
Driss Erguibi ◽  
Rachid Boufettal ◽  
Saad Rifki El Jai ◽  
...  

Primary anorectal malignant melanoma is an extremely rare condition. It appears at the third highest frequency after melanomas of the skin and retina. Its prognosis is dreadful because of the early onset of metastases. The treatment remains essentially surgical. We report an observation of primitive anorectal melanoma, collected at the department of surgery for digestive cancers and liver transplantation of the Ibn Rochd University Hospital of Casablanca, with a review of the literature. In order to analyse the clinical, paraclinical and therapeutic characteristics of primary anorectal melanoma.


Author(s):  
Pietro PERDUCA ◽  
Daniel Reis WAISBERG ◽  
Rafael Soares Nunes PINHEIRO ◽  
Eduardo Guimarães HOURNEAUX-DE-MOURA ◽  
Luiz Augusto Carneiro D’ALBUQUERQUE ◽  
...  

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