scholarly journals Messenger Ribonucleic Acid Vaccines for Severe Acute Respiratory Syndrome Coronavirus-2 – A Review

2021 ◽  
Author(s):  
Christine M. Akamine ◽  
Hana M. El Sahly
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Ribonucleic Acid ◽  
Messenger Ribonucleic Acid

scholarly journals Quantitative Measurement of Ovalbumin Messenger Ribonucleic Acid Activity

1973 ◽  
Vol 248 (6) ◽  
pp. 2031-2039 ◽  
Author(s):  
Robert E. Rhoads ◽  
G. Stanley McKnight ◽  
Robert T. Schimke
Keyword(s):  
Ribonucleic Acid ◽  
Quantitative Measurement ◽  
Messenger Ribonucleic Acid

scholarly journals Do Corticosteroid Injections for the Treatment of Pain Influence the Efficacy of mRNA COVID-19 Vaccines?

Pain Medicine ◽  
2021 ◽  
Vol 22 (4) ◽  
pp. 994-1000
Author(s):  
Haewon Lee ◽  
Jennifer A Punt ◽  
David C Miller ◽  
Ameet Nagpal ◽  
Clark C Smith ◽  
...  
Keyword(s):  
Hpa Axis ◽  
Ribonucleic Acid ◽  
Direct Evidence ◽  
Corticosteroid Injection ◽  
Vaccine Dose ◽  
Hypothalamic Pituitary Adrenal ◽  
Messenger Ribonucleic Acid ◽  
Corticosteroid Injections

Abstract Myth Corticosteroid injection for the treatment of pain and inflammation is known to decrease the efficacy of the messenger ribonucleic acid (mRNA) vaccines for coronavirus disease 2019 (COVID-19). Fact There is currently no direct evidence to suggest that a corticosteroid injection before or after the administration of an mRNA COVID-19 vaccine decreases the efficacy of the vaccine. However, based on the known timeline of hypothalamic-pituitary-adrenal (HPA) axis suppression following epidural and intraarticular corticosteroid injections, and the timeline of the reported peak efficacy of the Pfizer-BioNTech and Moderna vaccines, physicians should consider timing an elective corticosteroid injection such that it is administered no less than 2 weeks prior to a COVID-19 mRNA vaccine dose and no less than 1 week following a COVID-19 mRNA vaccine dose, whenever possible.

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