Evaluation of Coronary Flow Velocity Reserve in Homozygous Familial Hypercholesterolemia by Transthoracic Doppler Echocardiography and Dual-Source Computed Tomography

2010 ◽  
Vol 36 (10) ◽  
pp. 1756-1761 ◽  
Author(s):  
Ya Yang ◽  
Xiaoshan Zhang ◽  
Rongjuan Li ◽  
Hongyan Ren ◽  
Zheng Wang ◽  
...  
2015 ◽  
Vol 10 (1) ◽  
pp. 12 ◽  
Author(s):  
Iana Simova ◽  

Coronary flow velocity reserve (CFVR) reflects global coronary atherosclerotic burden, endothelial function and state of the microvasculature. It could be measured using transthoracic Doppler echocardiography in a non-invasive, feasible, reliable and reproducible fashion, following a standardised protocol with different vasodilatory stimuli. CFVR measurement is a recommended complement to vasodilator stress echocardiography. It could serve as a diagnostic tool for coronary microvascular dysfunction and in the setting of epicardial coronary artery stenoses could help in identification and assessment of functional significance of coronary lesions and follow-up of patients after coronary interventions. CFVR has also a prognostic significance in different clinical situations.


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