Time Course of Isoflurane-Induced Vasodilation: A Doppler Ultrasound Study of the Left Coronary Artery in Mice

2016 ◽  
Vol 42 (4) ◽  
pp. 999-1009 ◽  
Author(s):  
Francesca Lenzarini ◽  
Nicole Di Lascio ◽  
Francesco Stea ◽  
Claudia Kusmic ◽  
Francesco Faita
2001 ◽  
Vol 11 (1) ◽  
pp. 79-83 ◽  
Author(s):  
Luc Mertens ◽  
Frank Weidemann ◽  
George R. Sutherland

AbstractWe report an infant with an abnormal left coronary artery arising from the pulmonary trunk in whom, subsequent to surgical repair, sequential improvements in regional left and right systolic and diastolic myocardial function were quantified by the new ultrasound-based method of regional strain and strain rate imaging. The regional radial and longitudinal myocardial function of the left ventricle was homogeneously reduced prior to repair, while the time course of their recovery differed subsequent to repair. We discuss the concepts and advantages behind this quantitative approach to monitoring regional myocardial function in children.


2013 ◽  
Vol 16 (4) ◽  
pp. 210 ◽  
Author(s):  
Sachin Talwar ◽  
Aandrei Jivendra Jha ◽  
Shiv Kumar Choudhary ◽  
Saurabh Kumar Gupta ◽  
Balram Airan

Between January 2002 and December 2012, five patients (4 female) underwent corrective surgery for anomalous left coronary artery from pulmonary artery (ALCAPA). They were older than 1 year (range, 3-56 years). One of the 2 patients younger than 10 years had presented with congestive heart failure, and the other had experienced repeated episodes of lower respiratory tract infection since childhood. Of the remaining 3 adult patients, 2 had experienced angina with effort, and 1 patient had had repeated respiratory tract infections since childhood, with mild dyspnea on effort of New York Heart Association (NYHA) class II. Three patients had the anomalous left coronary artery implanted directly into the ascending aorta via coronary-button transfer, and 2 patients underwent coronary artery bypass with obliteration of the left main ostium. Two patients underwent concomitant mitral valve repair procedures, and 1 patient underwent direct closure of a perimembranous ventricular septal defect. Four patients survived the surgery, and 1 patient died because of a persistently low cardiac output. Follow-up times ranged from 3 months to 4 years. All survivors are in NYHA class I and have left ventricular ejection fractions of 45% to 60%, with moderate (n = 1), mild (n = 1), or no (n = 2) mitral insufficiency. We conclude that a few naturally selected patients with ALCAPA do survive beyond infancy and can undergo establishment of 2 coronary systems with satisfactory results.


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