Prognostic Factors for Chronic Kidney Disease After Curative Surgery in Patients With Small Renal Tumors

Urology ◽  
2009 ◽  
Vol 74 (5) ◽  
pp. 1064-1068 ◽  
Author(s):  
Hwang Gyun Jeon ◽  
In Gab Jeong ◽  
Jeong Woo Lee ◽  
Sang Eun Lee ◽  
Eunsik Lee
Keyword(s):  
Chronic Kidney Disease ◽  
Prognostic Factors ◽  
Kidney Disease ◽  
Renal Tumors ◽  
Curative Surgery

scholarly journals Identifying Influential Prognostic Factors of Death Hazard Rates in Patients with Chronic Kidney Disease (CKD) Using Weibull Model with Non-Constant Shape Parameter

2021 ◽  
Author(s):  
Seyede Solmaz Taheri ◽  
Ahmadreza Baghestani ◽  
Farzanehsadat Minoo ◽  
Anahita Saeedi
Keyword(s):  
Chronic Kidney Disease ◽  
Uric Acid ◽  
Prognostic Factors ◽  
Kidney Disease ◽  
Shape Parameter ◽  
Weibull Model ◽  
Hazard Rates ◽  
Time Interval ◽  
Stage Renal Disease ◽  
Constant Shape

Introduction: Chronic Kidney Disease (CKD) is a disease in which damaged kidneys could not remove waste material from the blood which could result in other health problems. The aim of this analysis was to identify significant laboratory prognostic factors on death hazard due to CKD. Methods: There were 109 patients with end-stage renal disease (ESRD) treated at Helal pharmaceutical and clinical complex. The survival time was set as the time interval from starting dialysis until death due to CKD. Age, gender and factors such as creatinine, cholesterol, uric acid, SGOT, SGPT, bilirubin, hemoglobin, potassium, ALP, HbA1C, ferritin, calcium, phosphorus, PTH and albumin were employed in this study. Weibull Distribution with non-Constant Shape Parameter versus constant Shape Parameter for the analysis were used. Results: Death due to CKD occurred in 29 (26.6%) of the patients. Sixty-seven (61.5%) had uric acid higher than 6.8 (mg/dl) and 39(35%) had phosphorus higher than 4.7 (mg/dl) which were poor prognoses. The incidence of death was 48.4%. Calcium<8.5 (mg/dl) (p=0.002), Calcium > 9.5 (mg/dl) (p=0.003), Albumin 4-6.3 (g/dl) (p=0.034), Phosphorus (p=0.022), hemoglobin<10 (g/dl) (p=0.043), hemoglobin>12.5 (g/dl) (p=0.006) and iPTH (p<0.001) were significant variables which had an effect on death hazard rates. Conclusion: The Weibull model with Non-Constant shape parameter was suggested to be more accurate for identifying risk factors, leading to more precise results, compared to constant shape parameter. Investigators mostly emphasize on the importance of Calcium, Albumin, Phosphorus, hemoglobin and iPTH for reducing hazard rates in CKD patients.  

The Clinical Course and Prognostic Factors of COVID-19 in Patients with Chronic Kidney Disease, A Study in Six Centers

2021 ◽  
Vol 15 (4) ◽  
Author(s):  
Sharzad Ossareh ◽  
Neda Najafi ◽  
Roghayeh Akbari ◽  
Zahra Lotfi ◽  
Atieh Makhough ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Prognostic Factors ◽  
Kidney Disease ◽  
Clinical Course

scholarly journals Renal outcomes and prognostic factors in patients with type-2 diabetes and chronic kidney disease confirmed by renal biopsy

2021 ◽  
Vol 12 ◽  
pp. 204062232110523
Author(s):  
Na Jing ◽  
Mengxing Pan ◽  
Yi Song ◽  
Feng Guo ◽  
Haohao Zhang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Chronic Kidney Disease ◽  
Prognostic Factors ◽  
Family History ◽  
Kidney Disease ◽  
Renal Disease ◽  
Family History Of Diabetes ◽  
Renal Outcomes ◽  
History Of

Aim: To evaluate the renal outcomes and prognostic factors among patients with type-2 diabetes (T2D) and biopsy-confirmed diabetic nephropathy (DN), non-diabetic renal disease (NDRD) and DN mixed with NDRD (MIX). Design and Methods: Patients with both T2D and chronic kidney disease (CKD) who underwent renal biopsy between January 2014 and December 2016 were recruited in this prospective observational study. Participants were divided into DN group, NDRD group, or MIX group according to the baseline pathological diagnosis. The primary endpoint was a composite renal event of end-stage renal disease (ESRD) or ⩾ 40% reduction in estimated glomerular filtration rate (eGFR). Results: Among the 292 participants included, 153 (52.4%) belonged to the DN group, 30 (10.3%) belonged to the NDRD group, and 109 (37.3%) belonged to the MIX group. During the median follow-up of 27 months, the adverse renal events occurred in 132 (44.2%) patients. Compared with NDRD group, the multiple adjusted hazard ratios (HRs) for renal events in patients with DN and MIX groups were 3.900 (95% confidence interval [CI]: 1.103–13.788) and 2.691 (95% CI: 0.662–10.936), respectively. Baseline lower eGFR (HR: 1.159, 95% CI: 1.060–1.266), severe proteinuria (HR: 2.047, 95% CI: 1.227–3.416), lower hemoglobin (HR: 1.170, 95% CI: 1.008–1.267), and a family history of diabetes (HR: 1.138, 95% CI: 1.008–2.285) were independent predictors for adverse renal outcomes in patients with DN. Conclusion: In patients with T2D and CKD, pure DN and MIX group displayed a worse renal prognosis than NDRD group. Worse renal function, severe proteinuria, lower hemoglobin, and a family history of diabetes may be associated with adverse renal outcomes in patients with DN.

1855 PREDICTIVE FACTORS OF NEW ONSET CHRONIC KIDNEY DISEASE AFTER RADICAL NEPHRECTOMY FOR CORTICAL RENAL TUMORS

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Fabio Torricelli ◽  
Alexandre Danilovic ◽  
Giovanni Marchini ◽  
Alexandre Sant'Anna ◽  
Marcos Dall'Oglio ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Predictive Factors ◽  
Radical Nephrectomy ◽  
Renal Tumors ◽  
New Onset

scholarly journals Should all patients with hypertension be worried about developing severe coronavirus disease 2019 (COVID-19)?

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Ramin Hosseinzadeh ◽  
Mohammad Ali Sheikh Beig Goharrizi ◽  
Mansour Bahardoust ◽  
Akbar Ghorbani Alvanegh ◽  
Mohammad Reza Ataee ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Prognostic Factors ◽  
Kidney Disease ◽  
Clinical Outcomes ◽  
Clinical Laboratory ◽  
P Value ◽  
Hypertensive Patients ◽  
Hospitalization Period ◽  
History Of ◽  
Poor Outcomes

Abstract Background Hypertension, the most common comorbidity among coronavirus disease 2019 (COVID-19) patients, is accompanied by worse clinical outcomes, but there is lack of evidence about prognostic factors among COVID-19 patients with hypertension. We have come up with some prognostic factors to predict the severity of COVID-19 among hypertensive patients. In addition, epidemiologic, clinical and laboratory differences among COVID-19 patients with and without underlying hypertension were evaluated. Methods Medical profiles of 598 COVID-19 cases were analyzed. Patients were divided into two comparative groups according to their positive or negative history of hypertension. Then, epidemiologic, clinical, laboratory and radiological features and also clinical outcomes were compared. Results 176 (29.4%) patients had underlying hypertension. Diabetes was significantly higher in hypertensive group [72 (40.9%) vs 76 (18%)] (P-value: 0.001). Cardiovascular and renal disorders were significantly higher in hypertensive patients. (P-value: 0.001 and 0.013 respectively). In COVID-19 patients with hypertension, severe/critical types were significantly higher. [42(23.8%) vs. 41(9.7%)], (P-value: 0.012). In the logistic regression model, Body mass index > 25 (ORAdj: 1.8, 95% CI: 1.2 to 2.42; P-value: 0.027), age over 60 (ORAdj: 1.26, 95% CI: 1.08 to 1.42; P-value: 0.021), increased hospitalization period (ORAdj: 2.1, 95% CI: 1.24 to 2.97; P-value: 0.013), type 2 diabetes (ORAdj: 2.22, 95% CI: 1.15 to 3.31; P-value: 0.001) and chronic kidney disease (ORAdj: 1.83, 95% CI: 1.19 to 2.21; P-value: 0.013) were related with progression of COVID-19. Conclusion Hypertensive patients with Age > 60-year-old, BMI > 25 Kg/m2, CVD, diabetes and chronic kidney disease are associated with poor outcomes in those with COVID-19 infection.

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