Efficient priming of simian/human immunodeficiency virus (SHIV)-specific T-cell responses with DNA encoding hybrid SHIV/hepatitis B surface antigen particles

Vaccine ◽  
2004 ◽  
Vol 22 (27-28) ◽  
pp. 3535-3545 ◽  
Author(s):  
Anne-Laure Puaux ◽  
Delphine Marsac ◽  
Stéphane Prost ◽  
Mandal K Singh ◽  
Patricia Earl ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
T Cell Responses ◽  
Dna Encoding ◽  
Cell Responses ◽  
Immunodeficiency Virus

Age is an important determinant in humoral and T cell responses to immunization with hepatitis B surface antigen

2013 ◽  
Vol 9 (7) ◽  
pp. 1466-1476 ◽  
Author(s):  
Carina Rosenberg ◽  
Nicolai V. Bovin ◽  
Lone Valentin Bram ◽  
Eigil Flyvbjerg ◽  
Mogens Erlandsen ◽  
...  
Keyword(s):  
T Cell ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Important Determinant ◽  
Hepatitis B Surface Antigen ◽  
T Cell Responses ◽  
Cell Responses

scholarly journals T cell responses to hepatitis B surface antigen are detectable in non-vaccinated individuals

2008 ◽  
Vol 14 (16) ◽  
pp. 2529 ◽  
Author(s):  
Martin R Weihrauch ◽  
Michael von Bergwelt-Baildon ◽  
Milos Kandic ◽  
Martin Weskott ◽  
Winfried Klamp ◽  
...  
Keyword(s):  
T Cell ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
T Cell Responses ◽  
Cell Responses

scholarly journals Reconstitution of Hepatitis B Virus (HBV)–Specific T Cell Responses with Treatment of Human Immunodeficiency Virus/HBV Coinfection

2003 ◽  
Vol 188 (12) ◽  
pp. 1815-1819 ◽  
Author(s):  
R. Monica Lascar ◽  
Richard J. Gilson ◽  
A. Ross Lopes ◽  
Antonio Bertoletti ◽  
Mala K. Maini
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hepatitis B Virus ◽  
T Cell ◽  
Hepatitis B ◽  
T Cell Responses ◽  
Cell Responses ◽  
B Virus ◽  
Immunodeficiency Virus

T-Cell Responses to Hepatitis B Surface Antigen in Lung Transplant Recipients

2007 ◽  
Vol 27 (9) ◽  
pp. 1248-1252 ◽  
Author(s):  
Mary S Hayney ◽  
Nicholas A Wiegert ◽  
Frances L Pelsue ◽  
Renee M Fohl ◽  
Ewa Jankowska-Gan ◽  
...  
Keyword(s):  
T Cell ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Lung Transplant ◽  
Hepatitis B Surface Antigen ◽  
T Cell Responses ◽  
Transplant Recipients ◽  
Cell Responses ◽  
Lung Transplant Recipients

HBV-specific T cell responses in low replicating inactive carrier patients are independent of Hepatitis B surface antigen load

2018 ◽  
Vol 68 ◽  
pp. S793-S794
Author(s):  
U.S. Gill ◽  
N. Hansi ◽  
N.L. Bert ◽  
K. Kunasegaran ◽  
G.E. Dolman ◽  
...  
Keyword(s):  
T Cell ◽  
Hepatitis B ◽  
Surface Antigen ◽  
Hepatitis B Surface Antigen ◽  
T Cell Responses ◽  
Inactive Carrier ◽  
Cell Responses

scholarly journals Maintenance of Viral Suppression in Human Immunodeficiency Virus Controllers Despite Waning T-Cell Responses During Antiretroviral Therapy

2020 ◽  
Vol 222 (11) ◽  
pp. 1837-1842 ◽  
Author(s):  
Nikolaus Jilg ◽  
Pilar Garcia-Broncano ◽  
Michael Peluso ◽  
Florencia P Segal ◽  
Ronald J Bosch ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Antiretroviral Therapy ◽  
T Cell Activation ◽  
Cell Activation ◽  
T Cell Responses ◽  
Cell Responses ◽  
Immunodeficiency Virus ◽  
Undetectable Viremia ◽  
Hiv Controllers

Abstract AIDS Clinical Trials Group study A5308 found reduced T-cell activation and exhaustion in human immunodeficiency virus (HIV) controllers start antiretroviral therapy (ART). We further assessed HIV-specific T-cell responses and post-ART viral loads. Before ART, the 31% of participants with persistently undetectable viremia had more robust HIV-specific T-cell responses. During ART, significant decreases were observed in a broad range of T-cell responses. Eight controllers in A5308 and the Study of the Consequences of the Protease Inhibitor Era (SCOPE) cohort showed no viremia above the level of quantification in the first 12 weeks after ART discontinuation. ART significantly reduced HIV-specific T-cell responses in HIV controllers but did not adversely affect controller status after ART discontinuation.

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