Salmonella Enteritidis ghost vaccine carrying the hemagglutinin globular head (HA1) domain from H1N1 virus protects against salmonellosis and influenza in chickens

Vaccine ◽  
2020 ◽  
Vol 38 (28) ◽  
pp. 4387-4394
Author(s):  
Gayeon Won ◽  
Amal Senevirathne ◽  
John Hwa Lee
Keyword(s):  
Salmonella Enteritidis ◽  
H1n1 Virus ◽  
Globular Head

scholarly journals A Broadly Neutralizing Human Monoclonal Antibody That Recognizes a Conserved, Novel Epitope on the Globular Head of the Influenza H1N1 Virus Hemagglutinin

2011 ◽  
Vol 85 (20) ◽  
pp. 10905-10908 ◽  
Author(s):  
J. C. Krause ◽  
T. Tsibane ◽  
T. M. Tumpey ◽  
C. J. Huffman ◽  
C. F. Basler ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
H1n1 Virus ◽  
Human Monoclonal Antibody ◽  
Influenza H1n1 ◽  
Globular Head

scholarly journals Globular Head-Displayed Conserved Influenza H1 Hemagglutinin Stalk Epitopes Confer Protection against Heterologous H1N1 Virus

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0153579 ◽  
Author(s):  
Miriam Klausberger ◽  
Rupert Tscheliessnig ◽  
Silke Neff ◽  
Raffael Nachbagauer ◽  
Teddy John Wohlbold ◽  
...  
Keyword(s):  
H1n1 Virus ◽  
Globular Head

Structure of Myosin Subfragment-1 from Electron Microscopy and Crystallography

1988 ◽  
Vol 46 ◽  
pp. 156-157
Author(s):  
Donald A. Winkelmann
Keyword(s):  
Electron Microscopy ◽  
Molecular Weight ◽  
Actin Filaments ◽  
Light Chains ◽  
Myosin Filament ◽  
Primary Role ◽  
Heavy Chains ◽  
Myosin Subfragment ◽  
Myosin Subfragment 1 ◽  
Globular Head

The primary role of the interaction of actin and myosin is the generation of force and motion as a direct consequence of the cyclic interaction of myosin crossbridges with actin filaments. Myosin is composed of six polypeptides: two heavy chains of molecular weight 220,000 daltons and two pairs of light chains of molecular weight 17,000-23,000. The C-terminal portions of the myosin heavy chains associate to form an α-helical coiled-coil rod which is responsible for myosin filament formation. The N-terminal portion of each heavy chain associates with two different light chains to form a globular head that binds actin and hydrolyses ATP. Myosin can be fragmented by limited proteolysis into several structural and functional domains. It has recently been demonstrated using an in vitro movement assay that the globular head domain, subfragment-1, is sufficient to cause sliding movement of actin filaments.The discovery of conditions for crystallization of the myosin subfragment-1 (S1) has led to a systematic analysis of S1 structure by x-ray crystallography and electron microscopy. Image analysis of electron micrographs of thin sections of small S1 crystals has been used to determine the structure of S1 in the crystal lattice.

Activation of isolated heterophils from chicks stimulated in vivo with salmonella enteritidis-immune lymphokines

1996 ◽  
Vol 54 ◽  
pp. 760-761
Author(s):  
R. B. Moyes ◽  
R. E. Droleskey ◽  
M. H. Kogut ◽  
J. R. DeLoach
Keyword(s):  
Lamina Propria ◽  
Intestinal Mucosa ◽  
Salmonella Enteritidis ◽  
Intestinal Tract ◽  
Polymorphonuclear Cells ◽  
Subclinical Infection ◽  
Egg Products ◽  
Immune Lymphokines ◽  
Organ Invasion

Salmonella enteritidis (SE) is of great concern to the poultry industry due to the organism's ability to penetrate the intestinal mucosa of the laying hen and subsequently colonize the ovaries and yolk membrane. The resultant subclinical infection can lead to SE infection of raw eggs and egg products. Interference with the ability of the organism to invade has been linked to the activation and recruitment of inflammatory polymorphonuclear cells, heterophils, to the lamina propria of the intestinal tract.Recently it has been established that heterophil activation and increased resistance to SE organ invasion can be accomplished by the administration of SE-immune lymphokines (SE-ILK) obtained from supernatants of concanavalin-A stimulated SE immune T lymphocytes from SE hyperimmunized hens. Invasion of SE into the lamina propria provides a secondary signal for directing activated heterophils to the site of SE invasion.

Sweet's syndrome associated with Salmonella enteritidis infection

1999 ◽  
Vol 24 (3) ◽  
pp. 239-240 ◽  
Author(s):  
Flórez ◽  
Sánchez-Aguilar ◽  
Rosón ◽  
Prieto ◽  
Van den Eyden ◽  
...  
Keyword(s):  
Salmonella Enteritidis ◽  
Sweet’S Syndrome ◽  
Sweet's Syndrome

H1N1 Virus Shedding Can Last Beyond 1 Week

2009 ◽  
Vol 39 (17) ◽  
pp. 1-24
Author(s):  
MITCHEL L. ZOLER
Keyword(s):  
H1n1 Virus ◽  
Virus Shedding
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