Effects of Mimosa tenuiflora on larval establishment of Haemonchus contortus in sheep

SUMMARYA Strain ofHaemonchus contortusshowing moderate levels of resistance to thiabendazole (TBZ) (egg hatch assay LC50 2.1 μM) was subjected, in alternating sequence, to 5 in vitro and 4 in vivo selections with TBZ. This resulted in a significant increase in resistance (egg hatch assay LC50 2.8 μM). The isolates obtained after each combined in vitro and in vivo selection were compared in terms of egg hatch assay, establishment, net egg output, per capita egg output and degree of pathology caused in infected hosts. The increase in resistance was accompanied by a significant increase in larval establishment sheep (22 %) and was associated with more severe pathology, higher egg count and worm recovery 3 months post- infection.

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in vivo anthelmintic activity of Syzygium cumini leaves against Haemonchus contortus in sheep

Planta Medica ◽

10.1055/s-0032-1321100 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

LDR Oliveira ◽

JPHV Miranda ◽

GS Curado ◽

JP Costa Neto ◽

BF Santos ◽

...

Keyword(s):

Haemonchus Contortus ◽

Anthelmintic Activity ◽

Syzygium Cumini

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Haemonchus contortus: in vivo anthelmintic activity of leaves of anacardium humile

Planta Medica ◽

10.1055/s-0032-1321116 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

LDR Oliveira ◽

JPHV Miranda ◽

GS Curado ◽

JP Costa Neto ◽

BF Santos ◽

...

Keyword(s):

Haemonchus Contortus ◽

Anthelmintic Activity

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Additional feeding of Asa foetida to sheep infested with Haemonchus contortus: Evaluation of fecal egg count and haematocrit

Planta Medica ◽

10.1055/s-0033-1352326 ◽

2013 ◽

Vol 79 (13) ◽

Author(s):

L Podstatzky ◽

R Chizzola ◽

GM Witschnig

Keyword(s):

Haemonchus Contortus ◽

Fecal Egg Count

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Effect of Jatropha curcas Latex on L3 Haemonchus contortus Larval Motility

International Journal of Pharmaceutical and Clinical Research ◽

10.25258/ijpcr.v9i3.8317 ◽

2017 ◽

Vol 9 (3) ◽

Cited By ~ 1

Author(s):

Noorzaid Muhamad ◽

Syahirah Sazeli ◽

Resni Mona ◽

Jannathul Firdous

Keyword(s):

Larvicidal Activity ◽

Jatropha Curcas ◽

Haemonchus Contortus ◽

Anthelmintic Resistance ◽

Small Ruminants ◽

Gastrointestinal Nematodes ◽

Dose Dependent ◽

Plants Extract

The anthelmintic resistance has limited the control of gastrointestinal nematodes of small ruminants and thus has awakened interest in the study of plants extract as a source of anthelmintics. These experiments were carried out to evaluate the in vitro efficacy of Jatrophacurcas latex extract against Haemonchuscontortus larval motility. To evaluate the larvicidal activity, H.contortus L3 were incubated with the extracts with varying concentration of 5 mg/mL, 10 mg/mL, 15 mg/mL and 20 mg/mL at 27°C for 48, 72 and 96 hrs. The results were subjected to the Kruskal-Wallis test (P less than 0.05). The extracts showed dose-dependent larvicidal effects. These results suggest that J.curcas can be used to control gastrointestinal nematodes of small ruminants.

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