Introduction. Chronic pancreatitis (CP) causes inflammatory changes in the
tissue of the pancreas, resulting in irreversible tissue damage. Pain,
endocrine, and exocrine pancreatic insufficiency develop, thereby reducing
the quality of life of patients. The study aims to explore the role of
surgical treatment in improving the quality of life of patients with CP.
Methods. Quality of life assessment of 50 patients diagnosed with CP was
performed using a certified Euro Quality of life-5 dimension-5 level
questionnaire translated into Serbian (EuroQol-5D-5L). Patients completed
the questionnaire. Patients were divided into two groups (conservative - CT
vs. surgical - ST), and all comparations was made between groups. Results.
Patients in stage B chronic pancreatitis were divided into two groups of 25
patients. The first group of patients with CP was treated with conservative,
and the second group with surgical approach. Mane age in surgically treated
(ST) group was 48.56 ? 11.91, and in conservatively treated (CT) group was
51.08 ? 11.61 (p=0.452). Male/female ratio in ST group was 18/7, and in CT
group was 22/3 (p=0.289). Pain in ST group was present in 23 patients, and
in CT group was present in 18 patients (p=0.141). Loss of appetite in ST
group was present in 7 patients, and in CT group was present in 10 patients
(p=0.256). Weight loss in both groups was equal (p=1.000). Based on
EuroQol-5D-5L it was found significant differences (p<0.001) between group
in Mobility and Pain / Discomfort; in Anxiety / Depression (p=0.003); in
Self-care (p=0.004); in Usual activities (p=0.008). Conclusion. CP
significantly reduce the quality of life (QoL) of patients treated
conservatively or by surgical approach. This study showed that surgical
treatment is more beneficial in QoL in patients with CP then conservative
approach
Quality of life assessment in patients treated with chronic pancreatitis
