High risk of anxiety and depression in caregivers of adult patients with epilepsy and its negative impact on patients' quality of life

AbstractIdentifying highly disabled patients or at high risk of psychiatric comorbidity is crucial for migraine management. The burden of migraine increases with headache frequency, but the number of headache days (HDs) per month after which disability becomes severe or the risk of anxiety and depression is higher has not been established. Here, we estimate the number of HDs per month after which migraine is associated with higher risk of anxiety and depression, severe disability and lower quality of life. We analysed 468 migraine patients (mean age 36.8 ± 10.7; 90.2% female), of whom 38.5% had ≥ 15 HDs per month. Our results show a positive linear correlation between the number of HDs per month and the risk of anxiety (r = 0.273; p < 0.001), depression (r = 0.337; p < 0.001) and severe disability (r = 0.519; p < 0.001). The risk of anxiety is higher in patients having ≥ 3HDs per month, and those with ≥ 19HDs per month are at risk of depression. Moreover, patients suffering ≥ 10HDs per month have very severe disability. Our results suggest that migraine patients with ≥ 10HDs per month are very disabled and also that those with ≥ 3HDs per month should be screened for anxiety.

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The effects of epileptic seizures upon quality of life

Journal of Epilepsy and Clinical Neurophysiology ◽

10.1590/s1676-26492009000300003 ◽

2009 ◽

Vol 15 (3) ◽

pp. 110-113 ◽

Cited By ~ 5

Author(s):

Priscila Camile Barioni Salgado ◽

Fernando Cendes

Keyword(s):

Quality Of Life ◽

Seizure Frequency ◽

Seizure Control ◽

Epileptic Seizures ◽

Anxiety And Depression ◽

Co Morbidity ◽

Item Quality ◽

Patients With Epilepsy ◽

And Control

OBJECTIVE: understand the psychological considerations of the relationship between the effect of seizures upon the patients' perception of seizure control, depression, anxiety and quality of life (QoL). METHODS: 151 adult patients with epilepsy diagnosed for over two years were interviewed and responded the 31-Item Quality of Life in Epilepsy (QOLIE-31), the Trait Form of the State/Trait Anxiety Inventory (STAI II) and the Beck Depression Inventory (BDI). RESULTS: 45 patients were depressed (29.8%) and 29 (19.2%) had anxiety. Depression scores ranged from 0 to 49 (M=7.4; SD=8.9) and anxiety scores ranged from 19 to 69 (M=41.5, SD=11.9). Total QoL score was correlated to seizure control (p<0.001), perception of epilepsy control (p<0.001), anxiety (p<0.001), and depression (p=0.003). The perception of epilepsy control was correlated to seizure control (p<0.001), seizure frequency (p=0.001), anxiety (p<0.001) and depression (p<0.001). Seizure control was associated to anxiety (p=0.033) and depression (p<0.001). There was co-morbidity between anxiety and depression (p<0.001). CONCLUSION: This study highlights the importance of the seizure frequency and control to the evaluation of perception of epilepsy control and shows that anxiety and depression in epilepsy are predicted by seizure-related (seizure frequency and control) and psychosocial aspects (perception of control and QoL) together.

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Influence of Occupational Status on the Quality of Life of Chinese Adult Patients with Epilepsy

Chinese Medical Journal ◽

10.4103/0366-6999.182827 ◽

2016 ◽

Vol 129 (11) ◽

pp. 1285-1290 ◽

Cited By ~ 8

Author(s):

Xiang-Min Gu ◽

Cheng-Yun Ding ◽

Ning Wang ◽

Cheng-Feng Xu ◽

Ze-Jie Chen ◽

...

Keyword(s):

Quality Of Life ◽

Occupational Status ◽

Adult Patients ◽

Chinese Adult ◽

Patients With Epilepsy

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Prevalence of Depression and Anxiety in Parkinson Disease and Impact on Quality of Life: A Community-Based Study in Spain

Journal of Geriatric Psychiatry and Neurology ◽

10.1177/0891988719874130 ◽

2019 ◽

Vol 33 (4) ◽

pp. 207-213 ◽

Cited By ~ 5

Author(s):

Fany Chuquilín-Arista ◽

Tania Álvarez-Avellón ◽

Manuel Menéndez-González

Keyword(s):

Quality Of Life ◽

Parkinson Disease ◽

Negative Impact ◽

Anxiety And Depression ◽

Sociodemographic Characteristics ◽

Depression And Anxiety ◽

Community Based ◽

Increased Risk ◽

Prevalence Of Depression

Background: Identifying neuropsychiatric disorders is essential for prompt treatment to reduce morbidity. Among these disorders, anxiety and depression have been frequently associated with Parkinson disease (PD), particularly among elderly population. Objective: The objective of this study is to determine the prevalence of anxiety and depression in a series of community-based PD cases in Spain, their relationship with different clinical and sociodemographic characteristics, and quality of life. Methods: This is an observational, descriptive, survey-based study with 95 community-based patients with PD diagnosis at different disease stages. Anxiety and depression were assessed using the State-Trait Anxiety Inventory and the Beck Depression Inventory II, respectively. Quality of life was assessed using the Parkinson’s Disease Questionnaire 39. Results: The prevalence of depression and anxiety was 32.63% and 68.42%, respectively. Concomitant depression and anxiety were observed in 31.58% of patients. Patients with longer than 10 years’ PD duration had an increased risk of depression. We found a relationship between the presence of anxiety, depression, and the patient’s quality of life. Conclusions: Depression is present in one-third and anxiety in two-thirds of PD cases in community settings in Spain. Depression and anxiety have a very negative impact on quality of life in PD. Both anxiety and depression are independent from sociodemographic characteristics, patient’s comorbidities, or antiparkinsonian treatments; presenting as intrinsic symptoms in PD.

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Quality of life, anxiety and depression in adult patients after add-on of levetiracetam and conversion to levetiracetam monotherapy

Epilepsy Research ◽

10.1016/j.eplepsyres.2012.08.005 ◽

2013 ◽

Vol 104 (1-2) ◽

pp. 140-150 ◽

Cited By ~ 13

Author(s):

Anne Hagemann ◽

Theodor W. May ◽

Esther Nieder ◽

Karin Witte-Bölt ◽

Bernd Pohlmann-Eden ◽

...

Keyword(s):

Quality Of Life ◽

Adult Patients ◽

Anxiety And Depression

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Quality of life and related factors in adult patients with epilepsy in China

Epilepsy & Behavior ◽

10.1016/j.yebeh.2011.07.025 ◽

2011 ◽

Vol 22 (2) ◽

pp. 376-379 ◽

Cited By ~ 21

Author(s):

Yongqing Zhao ◽

Huili Wu ◽

Jianguo Li ◽

Yueqing Dong ◽

Jin Liang ◽

...

Keyword(s):

Quality Of Life ◽

Adult Patients ◽

Related Factors ◽

Patients With Epilepsy

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Quality of life in 1931 adult patients with epilepsy: Seizures do not tell the whole story

Epilepsy & Behavior ◽

10.1016/j.yebeh.2011.08.039 ◽

2011 ◽

Vol 22 (4) ◽

pp. 723-727 ◽

Cited By ~ 38

Author(s):

Lara Jehi ◽

George Tesar ◽

Nancy Obuchowski ◽

Eric Novak ◽

Imad Najm

Keyword(s):

Quality Of Life ◽

Adult Patients ◽

Patients With Epilepsy

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Quality of Life in Adult Patients with Epilepsy

Epilepsia ◽

10.1111/j.1528-1157.1996.tb01818.x ◽

1996 ◽

Vol 37 (s3) ◽

pp. 37-40 ◽

Cited By ~ 19

Author(s):

Toshiaki Kugoh

Keyword(s):

Quality Of Life ◽

Adult Patients ◽

Patients With Epilepsy

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THE RELATIONSHIP OF QUALITY OF LIFE INDICATORS AND PSYCHOLOGICAL STATUS FEATURES IN CADETS OF THE UFA LAW INSTITUTE OF THE MINISTRY OF INTERNAL AFFAIRS OF THE RUSSIAN FEDERATION WITH CHRONIC GENERALIZED CATARRHAL GINGIVITIS

The actual problems in dentistry ◽

10.18481/2077-7566-2020-16-3-66-73 ◽

2020 ◽

Vol 16 (3) ◽

pp. 66-73

Author(s):

Olesya Sitdikova ◽

Milyausha Kabirova ◽

Oksana Gubina

Keyword(s):

Quality Of Life ◽

Physical Health ◽

Social Life ◽

Depressive Disorders ◽

Negative Impact ◽

Clinical Manifestations ◽

Well Being ◽

Psychological Status ◽

Anxiety And Depression

Subject. Chronic generalized catarrhal gingivitis affects the physical condition of a person, as well as the psychology of their behavior, emotional reactions, as well as their role in social life. Doctors are not always set up to assess the quality of life and patient satisfaction with the therapy. The peculiarity of this disease is the vastness of its clinical manifestations, and the need to start treatment in a timely manner, and patients taking medications themselves, affects poor adherence to treatment. These characteristics have an impact on the quality of life, and if the quality of life improves as a result of therapy, this motivates patients to effectively control their condition. Goal ― to assess the quality of life, frequency and severity of anxiety and depressive disorders in cadets with chronic generalized catarrhal gingivitis. Methodology. We conducted a survey of 140 cadets aged 18 to 25 years. Results.The revealed patterns suggest that bleeding, gum pain,and halitosis often contribute to the clinical manifestation of anxiety and depressive disorders in cadets with chronic generalized catarrhal gingivitis, thereby impairing the quality of life. The combination of various metabolic factors in a closed circle mutually increases the severity of not only clinical manifestations of chronic generalized catarrhal gingivitis, but also affects the mental status of the patient, increasing the degree of neurosis-like manifestations Conclusion. Chronic generalized catarrhal gingivitis significantly affects the decline in indicators of not only physical health, but also mental well-being. High levels of anxiety and depression are most significantly correlated with indicators of mental and physical health of cadets . Thus, anxiety and depression of a somatogenic nature has a negative impact on the quality of life, aggravates the course of the underlying disease, significantly affecting the General well-being of the patient.

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