Genetic pathogenesis of the epileptogenic lesions in Tuberous Sclerosis Complex: Therapeutic targeting of the mTOR pathway

2021 ◽  
pp. 107713
Author(s):  
Romina Moavero ◽  
Angelika Mühlebner ◽  
Mark Jasper Luinenburg ◽  
Dana Craiu ◽  
Eleonora Aronica ◽  
...  
Keyword(s):  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Mtor Pathway ◽  
Therapeutic Targeting

scholarly journals Therapeutic Targeting of the Secreted Lysophospholipase D Autotaxin Suppresses Tuberous Sclerosis Complex-Associated Tumorigenesis

2020 ◽  
Vol 80 (13) ◽  
pp. 2751-2763
Author(s):  
You Feng ◽  
William J. Mischler ◽  
Ashish C. Gurung ◽  
Taylor R. Kavanagh ◽  
Grigoriy Androsov ◽  
...  
Keyword(s):  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Therapeutic Targeting ◽  
Lysophospholipase D

Cardiac Rhabdomyomas in Tuberous Sclerosis Complex Show Apoptosis Regulation and mTOR Pathway Abnormalities

2009 ◽  
Vol 12 (2) ◽  
pp. 89-95 ◽  
Author(s):  
Katarzyna Kotulska ◽  
Magdalena Larysz-Brysz ◽  
Wiesława Grajkowska ◽  
Jarosław Jóźwiak ◽  
Paweł Włodarski ◽  
...  
Keyword(s):  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Mtor Pathway ◽  
Apoptosis Regulation

scholarly journals Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e57445 ◽  
Author(s):  
Bo Zhang ◽  
Sharon S. McDaniel ◽  
Nicholas R. Rensing ◽  
Michael Wong
Keyword(s):  
Mouse Model ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Mtor Pathway ◽  
Pathway Activation

scholarly journals Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex

2021 ◽  
Vol 81 (8) ◽  
pp. 2086-2100
Author(s):  
Andrii Kovalenko ◽  
Andres Sanin ◽  
Kosmas Kosmas ◽  
Long Zhang ◽  
Ji Wang ◽  
...  
Keyword(s):  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Therapeutic Targeting

scholarly journals Growth controls connect: Interactions between c-myc and the tuberous sclerosis complex-mTOR pathway

Cell Cycle ◽  
2009 ◽  
Vol 8 (9) ◽  
pp. 1344-1351 ◽  
Author(s):  
Emmett V. Schmidt ◽  
Michael J. Ravitz ◽  
Li Chen ◽  
Mary Lynch
Keyword(s):  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Mtor Pathway ◽  
Growth Controls

scholarly journals Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions

2011 ◽  
Vol 9 (5) ◽  
pp. 447-462 ◽  
Author(s):  
Laura Magri ◽  
Marco Cambiaghi ◽  
Manuela Cominelli ◽  
Clara Alfaro-Cervello ◽  
Marco Cursi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Mtor Pathway ◽  
Associated Lesions ◽  
Sustained Activation

Cardiac rhabdomyomas in tuberous sclerosis complex show apoptosis regulation and mTOR pathway abnormalities

2006 ◽  
Vol preprint (2007) ◽  
pp. 1
Author(s):  
Katarzyna Kotulska ◽  
Magdalena Larysz-Brysz ◽  
Wiesława Grajkowska ◽  
Jarosław Jóźwiak ◽  
Paweł Włodarski ◽  
...  
Keyword(s):  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Mtor Pathway ◽  
Apoptosis Regulation
Sign in / Sign up

Export Citation Format

Share Document