Prognostic Importance of the Cause of Renal Failure in Patients With Cirrhosis

2011 ◽  
Vol 2011 ◽  
pp. 259-260
Author(s):  
D.M. Harnois
Keyword(s):  
Renal Failure ◽  
Prognostic Importance

scholarly journals Liver Cirrhosis and Kidney

2016 ◽  
Vol 34 (4) ◽  
pp. 387-390 ◽  
Author(s):  
Alexander L. Gerbes
Keyword(s):  
Renal Failure ◽  
Liver Cirrhosis ◽  
Beta Blockers ◽  
Kidney Injury ◽  
Good Control ◽  
Intrahepatic Portosystemic Shunt ◽  
Prognostic Importance ◽  
Large Volume Paracentesis ◽  
Recent Attention

Background: Renal failure in cirrhosis may be due to various causes. While treatment for patients with ascites and hepatorenal syndrome is established, recent attention has been focused on acute kidney injury (AKI) in cirrhosis. Key Messages: The reduction of centrally effective blood volume is the key to the pathophysiology of renal failure and ascites formation in cirrhosis. Therefore, albumin infusion following large volume paracentesis is recommended by all guidelines. In selected patients, transjugular intrahepatic portosystemic shunt provides good control of ascites and improves survival. The role of non-selective beta-blockers in patients with cirrhosis and ascites is being controversially discussed. AKI in cirrhosis has been redefined and has prognostic importance. Conclusions: The role of kidney function in patients with liver cirrhosis is receiving increasing attention. In particular, the use of beta-blockers and novel definitions of AKI seem to be of clinical relevance.

scholarly journals The elderly patient with acute renal failure.

1995 ◽  
Vol 6 (2) ◽  
pp. 144-153
Author(s):  
J Pascual ◽  
F Liaño ◽  
J Ortuño
Keyword(s):  
Elderly Patient ◽  
Renal Failure ◽  
Renal Function ◽  
Acute Renal Failure ◽  
The Elderly ◽  
Functional Changes ◽  
Therapeutic Decisions ◽  
Prognostic Importance ◽  
Work Up ◽  
Aging Kidney

Structural and functional changes observed in the aging kidney predispose the elderly patient to acute renal failure. Up to 36% of the patients with acute renal failure from this institution were over 70 yr, and the literature is full of similar experiences. The elderly patient with abrupt cessation of adequate renal function requires a special work-up in diagnosis and treatment. Prerenal and obstructive causes are of particular interest. Although the question of whether or not age has an independent prognostic importance during an episode of acute renal failure remains debated; when these and other authors compared the outcome of young and old populations with these disorders, a similar evolution was always observed. Age should not be used as a discriminant factor in therapeutic decisions concerning acute renal failure.

Presentation, clinical behavior, outcomes and therapies for patients with advanced pancreas adenocarcinoma (PAC) who present with or develop ascites.

2016 ◽  
Vol 34 (4_suppl) ◽  
pp. 209-209
Author(s):  
Angel Mier Hicks ◽  
Eileen Mary O'Reilly ◽  
Marinela Capanu ◽  
Maeve Aine Lowery ◽  
Kenneth H. Yu
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Bowel Perforation ◽  
Malignant Ascites ◽  
Cancer Center ◽  
Poor Prognostic Factor ◽  
Indwelling Catheters ◽  
Bacterial Peritonitis ◽  
Catheter Malfunction ◽  
Prognostic Importance

209 Background: Ascites develops in a subset of patients with PAC at presentation or as the disease advances. Limited data exist on the prognostic importance of malignant ascites in PAC. Our hypothesis is that this information will provide an understanding of the natural history and facilitate management decisions. Methods: We conducted a retrospective analysis of N = 180 patients treated at Memorial Sloan Kettering Cancer Center diagnosed between January 1, 2009 and December 31, 2014, with PAC and ascites either at presentation or which developed during the disease course. Results: For the 180 patients, overall survival was 15 months. Time from diagnosis to ascites presentation was 11 months and survival time after ascites development was 4 months. Of 62 patients (34%) who had ascitic fluid analyzed, N = 36 (58%) had positive cytology, N = 51 (82%) patients had a serum ascites albumin gradient (SAAG) ≥ 1 and N = 11 (18%) had SAAG < 1.1. Sixty-four (36%) of patients had their ascites managed solely by serial paracenteses. A total of 116 patients required a catheter, from these, N = 108 (93%) had a Tenckhoff catheter, N = 4 (3%) Pleurx catheter, N = 3 (2%) Pigtail catheter and one (1%) a Denver catheter. Eight (4%) patients required two catheters to be placed and N = 6 (3%) Tenckhoff catheters had to be removed. Main observed complications: spontaneous bacterial peritonitis in N = 7 (11%) of patients managed with paracenteses vs. N = 34 (19%) who had a catheter placed, catheter malfunction in N = 8 (4%), acute renal failure in N = 6 (3%). After ascites development N = 79 (44%) of patients received active therapy and N = 101 (56%) patients were managed with supportive care alone. Conclusions: In patients with PAC the presence of ascites is a poor prognostic factor. Serial paracenteses and indwelling catheters are common methods used for alleviating patients’ discomfort. The complication rate was higher with indwelling catheters, primarily associated with infections (e.g. bacterial peritonitis) with low rates of complications occurring related to catheter malfunction, acute renal failure or bowel perforation.

scholarly journals Prognostic Importance of the Cause of Renal Failure in Patients With Cirrhosis

2011 ◽  
Vol 140 (2) ◽  
pp. 488-496.e4 ◽  
Author(s):  
Marta Martín–Llahí ◽  
Mónica Guevara ◽  
Aldo Torre ◽  
Claudia Fagundes ◽  
Tea Restuccia ◽  
...  
Keyword(s):  
Renal Failure ◽  
Prognostic Importance

scholarly journals Incidence and Prognostic Importance of Acute Renal Failure After Percutaneous Coronary Intervention

Circulation ◽  
2002 ◽  
Vol 105 (19) ◽  
pp. 2259-2264 ◽  
Author(s):  
Charanjit S. Rihal ◽  
Stephen C. Textor ◽  
Diane E. Grill ◽  
Peter B. Berger ◽  
Henry H. Ting ◽  
...  
Keyword(s):  
Renal Failure ◽  
Percutaneous Coronary Intervention ◽  
Acute Renal Failure ◽  
Coronary Intervention ◽  
Percutaneous Coronary ◽  
Prognostic Importance

Immunolabelling of glomerular deposits in kidney biopsies routinely fixed in glutaraldehyde

1989 ◽  
Vol 47 ◽  
pp. 910-911
Author(s):  
Ś Lhoták ◽  
I. Alexopoulou ◽  
G. T. Simon
Keyword(s):  
Uv Light ◽  
Kidney Diseases ◽  
Light Chains ◽  
Microscopical Level ◽  
Accurate Identification ◽  
Light Microscopical Level ◽  
Dense Deposits ◽  
Cacodylate Buffer ◽  
Glomerular Deposits ◽  
Prognostic Importance

Various kidney diseases are characterized by the presence of dense deposits in the glomeruli. The type(s) of immunoglobulins (Igs) present in the dense deposits are characteristic of the disease. The accurate Identification of the deposits is therefore of utmost diagnostic and prognostic importance. Immunofluorescence (IF) used routinely at the light microscopical level is unable to detect and characterize small deposits found in early stages of glomerulonephritis. Although conventional TEM is able to localize such deposits, it is not capable of determining their nature. It was therefore attempted to immunolabel at EM level IgG, IgA IgM, C3, fibrinogen and kappa and lambda Ig light chains commonly found in glomerular deposits on routinely fixed ( 2% glutaraldehyde (GA) in 0.1M cacodylate buffer) kidney biopsies.The unosmicated tissue was embedded in LR White resin polymerized by UV light at -10°C. A postembedding immunogold technique was employed

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