Clinical implications for MSI, MLH1 methylation analysis and IHC in Lynch screening for endometrial cancer patients: An analysis of 940 endometrioid endometrial cancer cases from the GOG 0210 study

2015 ◽  
Vol 137 ◽  
pp. 4-5
Author(s):  
C.C. Billingsley ◽  
D.E. Cohn ◽  
D.G. Mutch ◽  
R. Broaddus ◽  
N. Ramirez ◽  
...  
2010 ◽  
Vol 6 ◽  
pp. 937-944 ◽  
Author(s):  
Leszek Gottwald ◽  
Piotr Pluta ◽  
Janusz Piekarski ◽  
Michał Spych ◽  
Katarzyna Hendzel ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Yusuf Cakmak ◽  
Duygu Kavak Comert ◽  
Isik Sozen ◽  
Tufan Oge

After minimally invasive surgery gained popularity in gynecology, laparoscopic operations became widespread among oncologic operations. However, more studies evaluating experiences of oncologic surgeons during the learning period of laparoscopy are needed. To compare the surgical outcomes and perioperative complications of laparoscopic surgery and laparotomy in the treatment of early-stage endometrioid endometrial cancer patients, we retrospectively investigated patients who underwent surgery due to endometrial cancer at our institution between 2014 and 2018. Early-stage (stage I) endometrioid endometrial cancer patients were included in the study. Operative times, length of hospital stay, extracted pelvic lymph nodes, perioperative complications, and blood loss were compared. A total of 128 patients were treated for stage I endometrial cancer during the study period. Sixty-two patients (48.4%) underwent laparoscopic surgery, and 66 (51.6%) patients underwent laparotomy. Median operation time and pelvic lymph node count in the laparotomy and laparoscopy groups did not demonstrate statistically significant differences. However, the length of hospital stay, estimated blood loss, and perioperative complication rate were lower in the laparoscopic surgery group. Laparoscopic surgery in early-stage endometrial cancer may be performed with less blood loss, shorter duration of hospital stays, and similar lymph node counts compared to laparotomic surgery.


Cancer ◽  
2017 ◽  
Vol 123 (20) ◽  
pp. 4004-4012 ◽  
Author(s):  
Nicholas W. Bateman ◽  
Elizabeth A. Dubil ◽  
Guisong Wang ◽  
Brian L. Hood ◽  
Julie M. Oliver ◽  
...  

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