A phase I, single-arm, open-label, dose escalation study of intraperitoneal cisplatin and doxorubicin in patients with recurrent ovarian cancer and peritoneal carcinomatosis

Clemens B. Tempfer; Urs Giger-Pabst; Veronika Seebacher; Miriam Petersen; Askin Dogan; Günther A. Rezniczek

doi:10.1016/j.ygyno.2018.05.001

A phase I, single-arm, open-label, dose escalation study of intraperitoneal cisplatin and doxorubicin in patients with recurrent ovarian cancer and peritoneal carcinomatosis

Gynecologic Oncology ◽

10.1016/j.ygyno.2018.05.001 ◽

2018 ◽

Vol 150 (1) ◽

pp. 23-30 ◽

Cited By ~ 25

Author(s):

Clemens B. Tempfer ◽

Urs Giger-Pabst ◽

Veronika Seebacher ◽

Miriam Petersen ◽

Askin Dogan ◽

...

Keyword(s):

Ovarian Cancer ◽

Phase I ◽

Peritoneal Carcinomatosis ◽

Dose Escalation ◽

Recurrent Ovarian Cancer ◽

Open Label ◽

Dose Escalation Study ◽

Label Dose

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A Phase IB open-label, dose-escalation study of NUC‑1031 in combination with carboplatin for recurrent ovarian cancer

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-20-4403 ◽

2021 ◽

pp. clincanres.4403.2020

Author(s):

Farasat Kazmi ◽

Shibani Nicum ◽

Rene L Roux ◽

Laura Spiers ◽

Chat Gnanaranjan ◽

...

Keyword(s):

Ovarian Cancer ◽

Dose Escalation ◽

Recurrent Ovarian Cancer ◽

Open Label ◽

Dose Escalation Study ◽

Phase Ib ◽

Label Dose

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Abstract 1752: A phase I/IIa, first time in human, open-label dose-escalation study of GSK2636771 in subjects with advanced solid tumors with PTEN deficiency

10.1158/1538-7445.am2012-1752 ◽

2012 ◽

Cited By ~ 4

Author(s):

Samuel C. Blackman ◽

Shelby D. Gainer ◽

Benjamin B. Suttle ◽

Konstantine W. Skordos ◽

Joel D. Greshock ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Dose Escalation ◽

Advanced Solid Tumors ◽

Open Label ◽

Dose Escalation Study ◽

Label Dose ◽

First Time

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A first-in-human phase I, multicenter, open-label, dose-escalation study of the oral RAF/VEGFR-2 inhibitor (RAF265) in locally advanced or metastatic melanoma independent from BRAF mutation status

Cancer Medicine ◽

10.1002/cam4.1140 ◽

2017 ◽

Vol 6 (8) ◽

pp. 1904-1914 ◽

Cited By ~ 11

Author(s):

Benjamin Izar ◽

William Sharfman ◽

F. Stephen Hodi ◽

Donald Lawrence ◽

Keith T. Flaherty ◽

...

Keyword(s):

Phase I ◽

Metastatic Melanoma ◽

Dose Escalation ◽

Braf Mutation ◽

Locally Advanced ◽

Open Label ◽

Dose Escalation Study ◽

Mutation Status ◽

Label Dose

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Combination of CpG7909 and rituximab in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma (NHL): A phase I, open label dose-escalation study of safety and tolerability

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.6594 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 6594-6594

Author(s):

G. J. Weiner ◽

B. K. Link ◽

J. Leonard ◽

C. Emmanouilides ◽

G. Albert ◽

...

Keyword(s):

Phase I ◽

B Cell ◽

Dose Escalation ◽

Hodgkin’S Lymphoma ◽

Hodgkin's Lymphoma ◽

Open Label ◽

Dose Escalation Study ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma ◽

Label Dose

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Phase I, open-label, dose-escalation study of AZD7762 in combination with irinotecan (irino) in patients (pts) with advanced solid tumors.

Journal of Clinical Oncology ◽

10.1200/jco.2011.29.15_suppl.3033 ◽

2011 ◽

Vol 29 (15_suppl) ◽

pp. 3033-3033 ◽

Cited By ~ 19

Author(s):

A. L. Ho ◽

J. C. Bendell ◽

J. M. Cleary ◽

G. K. Schwartz ◽

H. A. Burris ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Dose Escalation ◽

Advanced Solid Tumors ◽

Open Label ◽

Dose Escalation Study ◽

Label Dose

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Abstract CT038: A phase I, open-label, dose-escalation study to investigate the safety, pharmacokinetics, pharmacodynamics, and clinical activity of GSK3326595 in subjects with solid tumors and non-Hodgkin's lymphoma

10.1158/1538-7445.am2017-ct038 ◽

2017 ◽

Cited By ~ 2

Author(s):

Drew Rasco ◽

Anthony Tolcher ◽

Lillian L. Siu ◽

Kimberley Heinhuis ◽

Sophie Postel-Vinay ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Dose Escalation ◽

Hodgkin’S Lymphoma ◽

Hodgkin's Lymphoma ◽

Clinical Activity ◽

Open Label ◽

Dose Escalation Study ◽

Non Hodgkin's Lymphoma ◽

Label Dose

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A Phase I, first-in-human, open label, dose escalation study of MGD007, a humanized gpA33 × CD3 dual-affinity re-targeting (DART®) protein in patients with relapsed/refractory metastatic colorectal carcinoma

Journal for ImmunoTherapy of Cancer ◽

10.1186/2051-1426-2-s3-p86 ◽

2014 ◽

Vol 2 (Suppl 3) ◽

pp. P86 ◽

Cited By ~ 7

Author(s):

Herbert Hurwitz ◽

Todd Crocenzi ◽

Joanna Lohr ◽

Ezio Bonvini ◽

Syd Johnson ◽

...

Keyword(s):

Colorectal Carcinoma ◽

Phase I ◽

Dose Escalation ◽

Metastatic Colorectal Carcinoma ◽

Open Label ◽

Dose Escalation Study ◽

Label Dose

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A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer

BMC Cancer ◽

10.1186/s12885-017-3641-6 ◽

2017 ◽

Vol 17 (1) ◽

Cited By ~ 8

Author(s):

Kerry Lynn Reynolds ◽

Philippe L. Bedard ◽

Se-Hoon Lee ◽

Chia-Chi Lin ◽

Josep Tabernero ◽

...

Keyword(s):

Gastric Cancer ◽

Monoclonal Antibody ◽

Squamous Cell Carcinoma ◽

Phase I ◽

Dose Escalation ◽

Advanced Squamous Cell Carcinoma ◽

Open Label ◽

Dose Escalation Study ◽

Carcinoma Of The Esophagus ◽

Label Dose

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Phase I, open-label, dose-escalation study of SNX-5422 plus everolimus in neuroendocrine tumors (NETs)

Annals of Oncology ◽

10.1093/annonc/mdw369.08 ◽

2016 ◽

Vol 27 ◽

pp. vi138

Author(s):

M.E. Gutierrez ◽

G. Giaccone ◽

S.V. Liu ◽

A. Rajan ◽

U. Guha ◽

...

Keyword(s):

Phase I ◽

Neuroendocrine Tumors ◽

Dose Escalation ◽

Open Label ◽

Dose Escalation Study ◽

Label Dose

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A Phase I, open-label, dose-escalation study of continuous once-daily oral treatment with afatinib in patients with advanced solid tumors

Investigational New Drugs ◽

10.1007/s10637-012-9904-9 ◽

2012 ◽

Vol 31 (2) ◽

pp. 409-416 ◽

Cited By ~ 28

Author(s):

Michael S. Gordon ◽

David S. Mendelson ◽

Mitchell Gross ◽

Martina Uttenreuther-Fischer ◽

Mahmoud Ould-Kaci ◽

...

Keyword(s):

Phase I ◽

Solid Tumors ◽

Dose Escalation ◽

Oral Treatment ◽

Advanced Solid Tumors ◽

Open Label ◽

Dose Escalation Study ◽

Once Daily ◽

Label Dose

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