Biochemical analysis of DNA synthesis blockage by G-quadruplex structure and bypass facilitated by a G4-resolving helicase

Methods ◽  
2021 ◽  
Author(s):  
Joshua A. Sommers ◽  
Katrina N. Estep ◽  
Robert W. Maul ◽  
Robert M. Brosh
2005 ◽  
Vol 127 (9) ◽  
pp. 2944-2959 ◽  
Author(s):  
Jeyaprakashnarayanan Seenisamy ◽  
Sridevi Bashyam ◽  
Vijay Gokhale ◽  
Hariprasad Vankayalapati ◽  
Daekyu Sun ◽  
...  

2020 ◽  
Vol 132 (13) ◽  
pp. 5331-5335
Author(s):  
Chun‐Yin Chan ◽  
Chun Kit Kwok

2011 ◽  
Vol 44 (13) ◽  
pp. S94-S95
Author(s):  
Zahra Karami ◽  
Bijan Ranjbar ◽  
Arastoo Badoei-Dalfard

2013 ◽  
Vol 41 ◽  
pp. 262-267 ◽  
Author(s):  
Hui Zhou ◽  
Zai-Sheng Wu ◽  
Guo-Li Shen ◽  
Ru-Qin Yu

2015 ◽  
Vol 51 (72) ◽  
pp. 13744-13747 ◽  
Author(s):  
Chang Yeol Lee ◽  
Ki Soo Park ◽  
Hyun Gyu Park

A G-quadruplex probe incorporating 2-AP is utilized to develop a novel strategy to accurately determine UDG activity. The excision reaction promoted by UDG is designed to trigger the formation of G-quadruplex structure with significant fluorescence enhancement of 2-AP within the probe. By employing this strategy, UDG activity can be reliably determined with high sensitivity and specificity.


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