Human plasma concentrations of herbicidal carbamate molinate extrapolated from the pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and physiologically based pharmacokinetic modeling

Chimeric Mice ◽

In Vivo Experiments ◽

Plasma concentrations of melengestrol acetate in humans extrapolated from the pharmacokinetics established in in vivo experiments with rats and chimeric mice with humanized liver and physiologically based pharmacokinetic modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2013.01.008 ◽

2013 ◽

Vol 65 (3) ◽

pp. 316-324 ◽

Cited By ~ 24

Author(s):

Ai Tsukada ◽

Hiroshi Suemizu ◽

Norie Murayama ◽

Ryohji Takano ◽

Makiko Shimizu ◽

...

Keyword(s):

Plasma Concentrations ◽

Chimeric Mice ◽

In Vivo Experiments ◽

Melengestrol Acetate ◽

Human Plasma Concentrations of Tolbutamide and Acetaminophen Extrapolated from in vivo Animal Pharmacokinetics Using in vitro Human Hepatic Clearances and Simple Physiologically Based Pharmacokinetic Modeling for Radio-labeled Microdose Clinical Studies

RADIOISOTOPES ◽

10.3769/radioisotopes.64.509 ◽

2015 ◽

Vol 64 (8) ◽

pp. 509-519 ◽

Cited By ~ 4

Author(s):

Hiroshi YAMAZAKI ◽

Eriko KUNIKANE ◽

Sayako NISHIYAMA ◽

Norie MURAYAMA ◽

Makiko SHIMIZU ◽

...

Keyword(s):

Human Plasma ◽

Clinical Studies ◽

Plasma Concentrations ◽

Physiologically Based ◽

Animal Pharmacokinetics

Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling

Xenobiotica ◽

10.3109/00498254.2016.1147102 ◽

2016 ◽

Vol 46 (12) ◽

pp. 1049-1055 ◽

Cited By ~ 26

Author(s):

Masahiro Utoh ◽

Hiroshi Suemizu ◽

Marina Mitsui ◽

Mirai Kawano ◽

Akiko Toda ◽

...

Keyword(s):

Cytochrome P450 ◽

Human Plasma ◽

Plasma Concentrations ◽

Human Hepatocytes ◽

Common Marmosets ◽

Human plasma concentrations of five cytochrome P450 probes extrapolated from pharmacokinetics in dogs and minipigs using physiologically based pharmacokinetic modeling

Xenobiotica ◽

10.3109/00498254.2015.1118650 ◽

2015 ◽

Vol 46 (9) ◽

pp. 759-764 ◽

Cited By ~ 11

Author(s):

Satomi Shida ◽

Hiroshi Yamazaki

Keyword(s):

Cytochrome P450 ◽

Human Plasma ◽

Plasma Concentrations ◽

Human plasma concentrations of cytochrome P450 probes extrapolated from pharmacokinetics in cynomolgus monkeys using physiologically based pharmacokinetic modeling

Xenobiotica ◽

10.3109/00498254.2015.1028511 ◽

2015 ◽

Vol 45 (10) ◽

pp. 881-886 ◽

Cited By ~ 15

Author(s):

Satomi Shida ◽

Masahiro Utoh ◽

Norie Murayama ◽

Makiko Shimizu ◽

Yasuhiro Uno ◽

...

Keyword(s):

Cytochrome P450 ◽

Human Plasma ◽

Plasma Concentrations ◽

Cynomolgus Monkeys ◽

Comment on M.V. Evans and J.C. Caldwell: Evaluation of two different metabolic hypotheses for dichloromethane toxicity using physiologically based pharmacokinetic modeling of in vivo gas uptake data exposure in female B6C3F1 mice, Toxicol. Appl. Pharmacol., 244, 280–290, 2010

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2010.07.012 ◽

2010 ◽

Vol 248 (1) ◽

pp. 63-64 ◽

Cited By ~ 2

Author(s):

M.W. Anders ◽

Melvin E. Andersen ◽

Harvey J. Clewell III ◽

Michael L. Gargas ◽

F. Peter Guengerich ◽

...

Keyword(s):

Gas Uptake ◽

Physiologically Based ◽

B6c3f1 Mice ◽

Uptake Data

Human urine and plasma concentrations of bisphenol A extrapolated from pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and semi-physiological pharmacokinetic modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2015.03.010 ◽

2015 ◽

Vol 72 (1) ◽

pp. 71-76 ◽

Cited By ~ 16

Author(s):

Takamori Miyaguchi ◽

Hiroshi Suemizu ◽

Makiko Shimizu ◽

Satomi Shida ◽

Sayako Nishiyama ◽

...

Keyword(s):

Bisphenol A ◽

Human Urine ◽

Plasma Concentrations ◽

Chimeric Mice ◽

In Vivo Experiments

Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo

Drug Metabolism and Disposition ◽

10.1124/dmd.116.069542 ◽

2016 ◽

Vol 44 (7) ◽

pp. 1123-1138 ◽

Cited By ~ 10

Author(s):

Q. J. Yang ◽

J. Fan ◽

S. Chen ◽

L. Liu ◽

H. Sun ◽

...

Keyword(s):

Flow Model ◽

Whole Body ◽

Metabolite Kinetics ◽

Segregated Flow ◽

Physiologically Based Pharmacokinetic Modeling of Benzene Metabolism in Mice Through Extrapolation from In Vitro to In Vivo

Journal of Toxicology and Environmental Health Part A ◽

10.1080/00984100150501178 ◽

2001 ◽

Vol 62 (6) ◽

pp. 439-465 ◽

Cited By ~ 18

Author(s):

Cammey E. Cole ◽

Hien T. Tran ◽

Paul M. Schlosser

Keyword(s):

Artemisinin Cocrystals for Bioavailability Enhancement. Part 2: In Vivo Bioavailability and Physiologically Based Pharmacokinetic Modeling

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.1c00385 ◽

2021 ◽

Author(s):

Manreet Kaur ◽

Vanessa Yardley ◽

Ke Wang ◽

Jinit Masania ◽

Randolph R. J. Arroo ◽

...

Keyword(s):

Bioavailability Enhancement ◽