Human Plasma Concentrations of Tolbutamide and Acetaminophen Extrapolated from <i>in vivo</i> Animal Pharmacokinetics Using <i>in vitro</i> Human Hepatic Clearances and Simple Physiologically Based Pharmacokinetic Modeling for Radio-labeled Microdose Clinical Studies

Physiologically Based ◽

Animal Pharmacokinetics

Human plasma concentrations of herbicidal carbamate molinate extrapolated from the pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and physiologically based pharmacokinetic modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2014.06.028 ◽

2014 ◽

Vol 70 (1) ◽

pp. 214-221 ◽

Cited By ~ 17

Author(s):

Masanao Yamashita ◽

Hiroshi Suemizu ◽

Norie Murayama ◽

Sayako Nishiyama ◽

Makiko Shimizu ◽

...

Keyword(s):

Human Plasma ◽

Plasma Concentrations ◽

Chimeric Mice ◽

In Vivo Experiments ◽

Plasma concentrations of melengestrol acetate in humans extrapolated from the pharmacokinetics established in in vivo experiments with rats and chimeric mice with humanized liver and physiologically based pharmacokinetic modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2013.01.008 ◽

2013 ◽

Vol 65 (3) ◽

pp. 316-324 ◽

Cited By ~ 24

Author(s):

Ai Tsukada ◽

Hiroshi Suemizu ◽

Norie Murayama ◽

Ryohji Takano ◽

Makiko Shimizu ◽

...

Keyword(s):

Plasma Concentrations ◽

Chimeric Mice ◽

In Vivo Experiments ◽

Melengestrol Acetate ◽

Physiologically Based Pharmacokinetic Modeling of Benzene Metabolism in Mice Through Extrapolation from In Vitro to In Vivo

Journal of Toxicology and Environmental Health Part A ◽

10.1080/00984100150501178 ◽

2001 ◽

Vol 62 (6) ◽

pp. 439-465 ◽

Cited By ~ 18

Author(s):

Cammey E. Cole ◽

Hien T. Tran ◽

Paul M. Schlosser

Keyword(s):

Blood Concentrations of 1,4-Dioxane in Humans after Oral Administration Extrapolated from In Vivo Rat Pharmacokinetics, In Vitro Human Metabolism, and Physiologically Based Pharmacokinetic Modeling

JOURNAL OF HEALTH SCIENCE ◽

10.1248/jhs.56.557 ◽

2010 ◽

Vol 56 (5) ◽

pp. 557-565 ◽

Cited By ~ 7

Author(s):

Ryohji Takano ◽

Norie Murayama ◽

Kana Horiuchi ◽

Masato Kitajima ◽

Fumiaki Shono ◽

...

Keyword(s):

Oral Administration ◽

Human Metabolism ◽

Blood Concentrations ◽

Blood concentrations of acrylonitrile in humans after oral administration extrapolated from in vivo rat pharmacokinetics, in vitro human metabolism, and physiologically based pharmacokinetic modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2010.06.008 ◽

2010 ◽

Vol 58 (2) ◽

pp. 252-258 ◽

Cited By ~ 22

Author(s):

Ryohji Takano ◽

Norie Murayama ◽

Kana Horiuchi ◽

Masato Kitajima ◽

Masatoshi Kumamoto ◽

...

Keyword(s):

Oral Administration ◽

Human Metabolism ◽

Blood Concentrations ◽

Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling

Xenobiotica ◽

10.3109/00498254.2016.1147102 ◽

2016 ◽

Vol 46 (12) ◽

pp. 1049-1055 ◽

Cited By ~ 26

Author(s):

Masahiro Utoh ◽

Hiroshi Suemizu ◽

Marina Mitsui ◽

Mirai Kawano ◽

Akiko Toda ◽

...

Keyword(s):

Cytochrome P450 ◽

Human Plasma ◽

Plasma Concentrations ◽

Human Hepatocytes ◽

Common Marmosets ◽

Human plasma concentrations of five cytochrome P450 probes extrapolated from pharmacokinetics in dogs and minipigs using physiologically based pharmacokinetic modeling

Xenobiotica ◽

10.3109/00498254.2015.1118650 ◽

2015 ◽

Vol 46 (9) ◽

pp. 759-764 ◽

Cited By ~ 11

Author(s):

Satomi Shida ◽

Hiroshi Yamazaki

Keyword(s):

Cytochrome P450 ◽

Human Plasma ◽

Plasma Concentrations ◽

CYP2B6 Pharmacogenetics–Based In Vitro–In Vivo Extrapolation of Efavirenz Clearance by Physiologically Based Pharmacokinetic Modeling

Drug Metabolism and Disposition ◽

10.1124/dmd.113.051755 ◽

2013 ◽

Vol 41 (12) ◽

pp. 2004-2011 ◽

Cited By ~ 19

Author(s):

Cong Xu ◽

Sara K. Quinney ◽

Yingying Guo ◽

Stephen D. Hall ◽

Lang Li ◽

...

Keyword(s):

Physiologically Based ◽

In Vivo Extrapolation

Addressing Early Life Sensitivity Using Physiologically Based Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation

Toxicological Research ◽

10.5487/tr.2016.32.1.015 ◽

2016 ◽

Vol 32 (1) ◽

pp. 15-20 ◽

Cited By ~ 11

Author(s):

Miyoung Yoon ◽

Harvey J. Clewell

Keyword(s):

Early Life ◽

Physiologically Based ◽

In Vivo Extrapolation

Human plasma concentrations of cytochrome P450 probes extrapolated from pharmacokinetics in cynomolgus monkeys using physiologically based pharmacokinetic modeling

Xenobiotica ◽

10.3109/00498254.2015.1028511 ◽

2015 ◽

Vol 45 (10) ◽

pp. 881-886 ◽

Cited By ~ 15

Author(s):

Satomi Shida ◽

Masahiro Utoh ◽

Norie Murayama ◽

Makiko Shimizu ◽

Yasuhiro Uno ◽

...

Keyword(s):

Cytochrome P450 ◽

Human Plasma ◽

Plasma Concentrations ◽

Cynomolgus Monkeys ◽