Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling

Human Hepatocytes ◽

Common Marmosets ◽

Human plasma concentrations of five cytochrome P450 probes extrapolated from pharmacokinetics in dogs and minipigs using physiologically based pharmacokinetic modeling

Xenobiotica ◽

10.3109/00498254.2015.1118650 ◽

2015 ◽

Vol 46 (9) ◽

pp. 759-764 ◽

Cited By ~ 11

Author(s):

Satomi Shida ◽

Hiroshi Yamazaki

Keyword(s):

Cytochrome P450 ◽

Human Plasma ◽

Plasma Concentrations ◽

Human plasma concentrations of cytochrome P450 probes extrapolated from pharmacokinetics in cynomolgus monkeys using physiologically based pharmacokinetic modeling

Xenobiotica ◽

10.3109/00498254.2015.1028511 ◽

2015 ◽

Vol 45 (10) ◽

pp. 881-886 ◽

Cited By ~ 15

Author(s):

Satomi Shida ◽

Masahiro Utoh ◽

Norie Murayama ◽

Makiko Shimizu ◽

Yasuhiro Uno ◽

...

Keyword(s):

Cytochrome P450 ◽

Human Plasma ◽

Plasma Concentrations ◽

Cynomolgus Monkeys ◽

Human Plasma Concentrations of Tolbutamide and Acetaminophen Extrapolated from in vivo Animal Pharmacokinetics Using in vitro Human Hepatic Clearances and Simple Physiologically Based Pharmacokinetic Modeling for Radio-labeled Microdose Clinical Studies

RADIOISOTOPES ◽

10.3769/radioisotopes.64.509 ◽

2015 ◽

Vol 64 (8) ◽

pp. 509-519 ◽

Cited By ~ 4

Author(s):

Hiroshi YAMAZAKI ◽

Eriko KUNIKANE ◽

Sayako NISHIYAMA ◽

Norie MURAYAMA ◽

Makiko SHIMIZU ◽

...

Keyword(s):

Human Plasma ◽

Clinical Studies ◽

Plasma Concentrations ◽

Physiologically Based ◽

Animal Pharmacokinetics

Human plasma concentrations of herbicidal carbamate molinate extrapolated from the pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and physiologically based pharmacokinetic modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2014.06.028 ◽

2014 ◽

Vol 70 (1) ◽

pp. 214-221 ◽

Cited By ~ 17

Author(s):

Masanao Yamashita ◽

Hiroshi Suemizu ◽

Norie Murayama ◽

Sayako Nishiyama ◽

Makiko Shimizu ◽

...

Keyword(s):

Human Plasma ◽

Plasma Concentrations ◽

Chimeric Mice ◽

In Vivo Experiments ◽

Plasma concentrations of melengestrol acetate in humans extrapolated from the pharmacokinetics established in in vivo experiments with rats and chimeric mice with humanized liver and physiologically based pharmacokinetic modeling

Regulatory Toxicology and Pharmacology ◽

10.1016/j.yrtph.2013.01.008 ◽

2013 ◽

Vol 65 (3) ◽

pp. 316-324 ◽

Cited By ~ 24

Author(s):

Ai Tsukada ◽

Hiroshi Suemizu ◽

Norie Murayama ◽

Ryohji Takano ◽

Makiko Shimizu ◽

...

Keyword(s):

Plasma Concentrations ◽

Chimeric Mice ◽

In Vivo Experiments ◽

Melengestrol Acetate ◽

Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-016-0412-5 ◽

2016 ◽

Vol 55 (11) ◽

pp. 1435-1445 ◽

Cited By ~ 16

Author(s):

Nageshwar R. Budha ◽

Tao Ji ◽

Luna Musib ◽

Steve Eppler ◽

Mark Dresser ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

Modeling And Simulation ◽

Interaction Potential ◽

Cytochrome P450 3A4 ◽

Physiologically Based ◽

Drug Drug Interaction

Predicting the Effect of Cytochrome P450 Inhibitors on Substrate Drugs: Analysis of Physiologically Based Pharmacokinetic Modeling Submissions to the US Food and Drug Administration

Clinical Pharmacokinetics ◽

10.1007/s40262-014-0188-4 ◽

2014 ◽

Vol 54 (1) ◽

pp. 117-127 ◽

Cited By ~ 70

Author(s):

Christian Wagner ◽

Yuzhuo Pan ◽

Vicky Hsu ◽

Joseph A. Grillo ◽

Lei Zhang ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Administration ◽

Food And Drug Administration ◽

The Us ◽

Physiologically Based ◽

Drugs Analysis ◽

P450 Inhibitors

Physiologically-Based Pharmacokinetic Modeling and Simulation to Assess Potential Cytochrome P450 3A4 and Transporter-Mediated Drug−drug Interactions with Prucalopride as Victim

10.26226/morressier.57d6b2b9d462b8028d88ea6f ◽

2016 ◽

Author(s):

Aiqun Li

Keyword(s):

Cytochrome P450 ◽

Drug Interactions ◽

Modeling And Simulation ◽

Cytochrome P450 3A4 ◽

Pharmacokinetic Modeling And Simulation

Physiologically Based ◽

Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling

Pediatric Research ◽

10.1038/s41390-019-0609-z ◽

2019 ◽

Vol 87 (3) ◽

pp. 441-449 ◽

Cited By ~ 1

Author(s):

Gaëlle Magliocco ◽

Frédérique Rodieux ◽

Jules Desmeules ◽

Caroline Flora Samer ◽

Youssef Daali

Keyword(s):

Cytochrome P450 ◽

Precision Medicine ◽

Pediatric Population ◽

Meta-analysis of hepatic cytochrome P450 ontogeny to underwrite the prediction of pediatric pharmacokinetics using physiologically based pharmacokinetic modeling

The Journal of Clinical Pharmacology ◽

10.1002/jcph.585 ◽

2015 ◽

Vol 56 (3) ◽

pp. 266-283 ◽

Cited By ~ 44

Author(s):

Vijay V. Upreti ◽

Jan L. Wahlstrom

Keyword(s):

Cytochrome P450 ◽

Meta Analysis ◽

Physiologically Based ◽

Hepatic Cytochrome