Altering behavioral responses and dopamine transporter protein with antisense peptide nucleic acids 1 1Abbreviations: DAT, dopamine transporter; and PNA, peptide nucleic acid.

2001 ◽  
Vol 62 (7) ◽  
pp. 929-932 ◽  
Author(s):  
Beth M Tyler-McMahon ◽  
Jennifer A Stewart ◽  
Joshua Jackson ◽  
M.D Bitner ◽  
Abdul Fauq ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Dopamine Transporter ◽  
Peptide Nucleic Acid ◽  
Peptide Nucleic Acids ◽  
Behavioral Responses ◽  
Transporter Protein ◽  
Antisense Peptide

Molecular insights on the dynamic stability of peptide nucleic acid functionalized carbon and boron nitride nanotubes

2021 ◽  
Vol 23 (1) ◽  
pp. 219-228
Author(s):  
Nabanita Saikia ◽  
Mohamed Taha ◽  
Ravindra Pandey
Keyword(s):  
Nucleic Acid ◽  
Boron Nitride ◽  
Nucleic Acids ◽  
Dynamic Stability ◽  
Peptide Nucleic Acid ◽  
Rational Design ◽  
Peptide Nucleic Acids ◽  
Boron Nitride Nanotubes ◽  
Molecular Hybrids ◽  
Single Wall Nanotubes

The rational design of self-assembled nanobio-molecular hybrids of peptide nucleic acids with single-wall nanotubes rely on understanding how biomolecules recognize and mediate intermolecular interactions with the nanomaterial's surface.

scholarly journals Peptide Nucleic Acids: Applications in Biomedical Sciences

Molecules ◽  
2020 ◽  
Vol 25 (15) ◽  
pp. 3317
Author(s):  
Eylon Yavin
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Peptide Nucleic Acid ◽  
Peptide Nucleic Acids ◽  
Biomedical Sciences

The DNA mimic, PNA (peptide nucleic acid), has been with us now for almost 3 decades [...]

Synthesis of nucleobase-caged peptide nucleic acids having improved photochemical properties

2014 ◽  
Vol 12 (28) ◽  
pp. 5089-5093 ◽  
Author(s):  
Takayoshi Watanabe ◽  
Tomoko Hoshida ◽  
Jun Sakyo ◽  
Mariko Kishi ◽  
Satoshi Tanabe ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Peptide Nucleic Acid ◽  
Peptide Nucleic Acids ◽  
Photochemical Properties ◽  
Caged Peptide

A nucleobase-caged peptide nucleic acid (PNA) having a (6-bromo-7-methoxycoumarin)-4-ylmethoxycarbonyl (Bmcmoc) caging group was newly synthesized.

scholarly journals Strand displacement and duplex invasion into double-stranded DNA by pyrrolidinyl peptide nucleic acids

2015 ◽  
Vol 13 (35) ◽  
pp. 9223-9230 ◽  
Author(s):  
Peggy R. Bohländer ◽  
Tirayut Vilaivan ◽  
Hans-Achim Wagenknecht
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Peptide Nucleic Acid ◽  
Peptide Nucleic Acids ◽  
Dna Duplexes ◽  
Strand Displacement ◽  
Nucleic Acid Probes ◽  
Double Stranded Dna

Strand displacement and duplex invasion of DNA duplexes by pyrrolidinyl peptide nucleic acid are demonstrated using the concept of wavelength-shifting nucleic acid probes.

scholarly journals Special Issue: Molecular Properties and the Applications of Peptide Nucleic Acids

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 1977 ◽  
Author(s):  
Roberto Corradini
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Peptide Nucleic Acid ◽  
Peptide Nucleic Acids ◽  
Molecular Properties ◽  
Special Issue ◽  
Science Paper

Polyamide analogs of DNA, or peptide nucleic acid (PNA), were first proposed in 1991 by a group of chemists and biochemists in a memorable Science paper [1].[…]

Addressing the challenges of cellular delivery and bioavailability of peptide nucleic acids (PNA)

2005 ◽  
Vol 38 (4) ◽  
pp. 345-350 ◽  
Author(s):  
Peter E. Nielsen
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acid ◽  
Peptide Nucleic Acids ◽  
Cell Penetrating Peptides ◽  
Endosomal Escape ◽  
Cellular Delivery ◽  
Peptide Conjugation ◽  
Cell Penetrating ◽  
Antisense Peptide

1. Introduction 3452. Peptide nucleic acid (PNA) 3463. ‘Cell penetrating peptides’ (CPPs) 3464. Endosomal escape 3475. Cellular delivery of PNA 3476.In vivobioavailability of PNA 3497. References 350Recent results on the cellular delivery of antisense peptide nucleic acids (PNA) via peptide conjugation is briefly discussed, in particular in the context of endosomal entrapment and escape.

scholarly journals Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions

2015 ◽  
Vol 13 (45) ◽  
pp. 11052-11071 ◽  
Author(s):  
Reuben Ovadia ◽  
Aurélien Lebrun ◽  
Ivan Barvik ◽  
Jean-Jacques Vasseur ◽  
Carine Baraguey ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Structural Characterization ◽  
Peptide Nucleic Acid ◽  
Multicomponent Reactions ◽  
Peptide Nucleic Acids ◽  
Solution Phase ◽  
Phase Synthesis ◽  
Solution Phase Synthesis

A solution phase synthesis of peptide nucleic acid monomers and dimers was developed by using microwave-promoted Ugi multicomponent reactions.

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