Neuroprotective action of group I metabotropic glutamate receptor agonists against oxygen–glucose deprivation-induced neuronal death

2000 ◽  
Vol 853 (2) ◽  
pp. 370-373 ◽  
Author(s):  
Anti Kalda ◽  
Allen Kaasik ◽  
Vitali Vassiljev ◽  
Paavo Pokk ◽  
Alexander Zharkovsky
Keyword(s):  
Glutamate Receptor ◽  
Neuronal Death ◽  
Metabotropic Glutamate Receptor ◽  
Glucose Deprivation ◽  
Oxygen Glucose Deprivation ◽  
Receptor Agonists ◽  
Metabotropic Glutamate ◽  
Group I ◽  
Glutamate Receptor Agonists ◽  
Neuroprotective Action

scholarly journals Metabotropic glutamate receptor agonists for schizophrenia

2008 ◽  
Vol 192 (2) ◽  
pp. 86-87 ◽  
Author(s):  
Paul J. Harrison
Keyword(s):  
Glutamate Receptors ◽  
Dopamine Receptor ◽  
Glutamate Receptor ◽  
Metabotropic Glutamate Receptors ◽  
Metabotropic Glutamate Receptor ◽  
Receptor Blocking ◽  
Receptor Agonists ◽  
Metabotropic Glutamate ◽  
Glutamate Receptor Agonists

SummaryA drug acting at metabotropic glutamate receptors has recently been reported to be an effective antipsychotic, breaking the rule that only dopamine receptor-blocking drugs have this property. The finding complements accumulating evidence that glutamatergic abnormalities are important in the pathophysiology of schizophrenia.

Sign in / Sign up

Export Citation Format

Share Document