Electroretinographic and visual evoked potentials changes in children with optic pathway tumours

Visual evoked potentials (VEPs) have a role in evaluating patients with neurologic disease affecting the optic pathway. In patients with lesions involving the optic nerve and anterior chiasm, VEPs have several important advantages: (1) they are objective and reproducible and may demonstrate a functional abnormality that is not evident on physical examination or with neuroimaging studies; (2) abnormalities may persist over time even when there is clinical resolution of visual symptoms; (3) they may be a more reliable indicator of disease than MRI, (4) they may be more sensitive than MRI for detecting abnormalities in optic nerves; and (5) they are less expensive than MRI studies and can be used in situations where MRI studies are contraindicated (i.e., pacemakers, aneurysm clips, etc). This chapter discusses the technical aspects, limitations, and roles of VEPs in the evaluation of neurologic symptoms.

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P3-p22 Role of diffusion tensor imaging and visual evoked potentials in brain tumor surgery adjacent to the optic pathway

Neuroscience Research ◽

10.1016/j.neures.2010.07.1906 ◽

2010 ◽

Vol 68 ◽

pp. e430

Author(s):

Keiji Shimizu ◽

Yu Kawanishi ◽

Motonobu Nonaka ◽

Eiichi Nakai ◽

Syohta Kitahara ◽

...

Keyword(s):

Brain Tumor ◽

Diffusion Tensor Imaging ◽

Evoked Potentials ◽

Visual Evoked Potentials ◽

Diffusion Tensor ◽

Optic Pathway ◽

Tumor Surgery ◽

Brain Tumor Surgery ◽

Visual Evoked

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A.02 Assessing visual functions in children with an optic pathway glioma using steady-state visual evoked potentials

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/cjn.2017.66 ◽

2017 ◽

Vol 44 (S2) ◽

pp. S8-S9

Author(s):

S Zakaib Rassi ◽

L Ospina ◽

Y Samson ◽

D Saint-Amour ◽

S Perreault

Keyword(s):

Steady State ◽

Visual Field ◽

Evoked Potentials ◽

Visual Evoked Potentials ◽

Visual Fields ◽

Optic Pathway Glioma ◽

Optic Pathway ◽

Central Visual Field ◽

Non Invasive ◽

Visual Evoked

Background: Optic pathway gliomas (OPG) represent 5% of pediatric brain tumours. Visual acuity measures are used to evaluate treatment response. Current clinical tests to assess visual field integrity are subjective and require verbal cooperation. Thus, the objective of this study was to evaluate the clinical effectiveness of Steady State Visual Evoked Potentials (ssVEPs) to measure visual field integrity in a non-invasive and objective manner. Methods: SsVEPs were obtained in ten children with OPGs and 42 controls ages 3 to 21. The stimuli consisted of two circular dartboard patterns stimulating fovea and peripheral zones at two flickering frequencies, so that central and peripheral visual fields could be assessed simultaneously. The test consisted of eight stimuli presentations of 10 seconds. Results: Results indicate significantly lower ssVEP amplitudes in children with OPGs (M=2.52, 95% CI [1.13, 3.92]) compared to controls (M=13.26, 95% CI [8.85, 17.67]) in the central visual field (p=.021). However, no between group differences were detected in the peripheral field (p >.05). There were no significant differences between age groups (p>0.05). Conclusions: This objective, affordable, and non-invasive method appears to be effective in detecting central visual field deficits in children with OPGs rapidly and consistently.

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