Significantly higher salivary bicarbonate and non-bicarbonate output during the upper esophageal mucosal exposure to acid and pepsin could be a factor in prevention of the upper esophagal mucosal injury during gastroesophageal reflux

2000 ◽  
Vol 118 (4) ◽  
pp. A33
Author(s):  
Cezary Poplawski ◽  
Mazen Asadi ◽  
Tomasz Skoczylas ◽  
Michele Loftiss ◽  
Jerzy Sarosiek
Author(s):  
Khaled Hassan

Gastroesophageal reflux is defined as a common physiologic phenomenon encountered intermittently by a large population, especially following a feed. Gastroesophageal reflux disease (GERD) happens if the number of gastric juices that refluxes into the esophagus passes the accepted limit, making symptoms with or without correlated esophageal mucosal injury (i.e., esophagitis). Diagnosis and treatment guidelines of gastroesophageal reflux disease (GERD) were announced in 1995 and updated in 2005 and lastly reviewed in 2013 by the American College of Gastroenterology (ACG). These and other guidelines undergo periodic review. Advances continue to be made in GERD, leading us to review and revise previous guideline statements. Here we aimed to review the different updated guidelines of diagnosis and treatment of Gastroesophageal reflux disease (GERD). A web-based search utilizing the advanced characteristics of different databases like PubMed, Google Scholar, Embase, Scopus, and Cochrane electronic databases was carried out. Keywords: Gastroesophageal reflux disease (GERD), Updates, Guidelines, Diagnosis, and Treatment.


2014 ◽  
Vol 59 (10) ◽  
pp. 2411-2416 ◽  
Author(s):  
Tomasz Skoczylas ◽  
Harathi Yandrapu ◽  
Cezary Poplawski ◽  
Mazen Asadi ◽  
Grzegorz Wallner ◽  
...  

Author(s):  
Khaled Hassan

Background: Gastroesophageal reflux is defined as a common physiologic phenomenon encountered intermittently by a large population, especially following a feed. Gastroesophageal reflux disease (GERD) happens if the number of gastric juice that refluxes into the esophagus passes the accepted limit, making symptoms with or without correlated esophageal mucosal injury (i.e., esophagitis). Diagnosis and treatment guidelines of gastroesophageal reflux disease (GERD) were announced in 1995 and updated in 2005 and lastly reviewed in 2013 by the American College of Gastroenterology (ACG). These and other guidelines undergo periodic review. Advances continue to be made in GERD, leading us to review and revise previous guideline statements. Here we aimed to review the different updated guidelines of diagnosis and treatment of Gastroesophageal reflux disease (GERD). A web-based search utilizing the advanced characteristics of different databases like PubMed, Google Scholar, Embase, Scopus, and Cochrane electronic databases was carried out. Keywords: Gastroesophageal reflux disease (GERD), Updates, Guidelines, Diagnosis, and Treatment.


2020 ◽  
Vol 115 (1) ◽  
pp. S221-S222
Author(s):  
Christopher A. Toivonen ◽  
Yazan Addasi ◽  
Sirish Rao ◽  
Ryan Walters ◽  
Kalyana Nandipati ◽  
...  

2015 ◽  
Vol 31 (6) ◽  
pp. 320-327 ◽  
Author(s):  
Chung-Hsien Li ◽  
Tsung-Cheng Hsieh ◽  
Tsung-Hsien Hsiao ◽  
Pin-Chao Wang ◽  
Tai-Chung Tseng ◽  
...  

2011 ◽  
Vol 21 (3) ◽  
pp. 89-99
Author(s):  
Michael F. Vaezi

Gastroesophageal reflux disease (GERD) is a commonly diagnosed condition often associated with the typical symptoms of heartburn and regurgitation, although it may present with atypical symptoms such as chest pain, hoarseness, chronic cough, and asthma. In most cases, the patient's reduced quality of life drives clinical care and diagnostic testing. Because of its widespread impact on voice and swallowing function as well as its social implications, it is important that speech-language pathologists (SLPs) understand the nature of GERD and its consequences. The purpose of this article is to summarize the nature of GERD and GERD-related complications such as GERD-related peptic stricture, Barrett's esophagus and adenocarcinoma, and laryngeal manifestations of GERD from a gastroenterologist's perspective. It is critical that SLPs who work with a multidisciplinary team understand terminology, diagnostic tools, and treatment to ensure best practice.


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