Helicobacter pylori alters API, OCT1, AND NF-k B DNA-binding activity and pERK expression in gastric epithelial cells

2000 ◽  
Vol 118 (4) ◽  
pp. A868
Author(s):  
Hassan Ashktorab ◽  
Caren Bancroft ◽  
Matthew Neapolitano ◽  
Cornell R. Allen ◽  
Andre Dubois ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Dna Binding ◽  
Epithelial Cells ◽  
Binding Activity ◽  
Gastric Epithelial Cells ◽  
Dna Binding Activity ◽  
Perk Expression

scholarly journals CbpA Acts as a Modulator of HspR Repressor DNA Binding Activity in Helicobacter pylori

2011 ◽  
Vol 193 (20) ◽  
pp. 5629-5636 ◽  
Author(s):  
D. Roncarati ◽  
A. Danielli ◽  
V. Scarlato
Keyword(s):  
Helicobacter Pylori ◽  
Dna Binding ◽  
Binding Activity ◽  
Dna Binding Activity

Ozone-induced IL-8 expression and transcription factor binding in respiratory epithelial cells

1997 ◽  
Vol 272 (3) ◽  
pp. L504-L511 ◽  
Author(s):  
I. Jaspers ◽  
E. Flescher ◽  
L. C. Chen
Keyword(s):  
Transcription Factors ◽  
Dna Binding ◽  
Epithelial Cells ◽  
Inflammatory Cells ◽  
Binding Activity ◽  
Ozone Exposure ◽  
Air Exposure ◽  
Dna Binding Activity ◽  
Nf Kappab

Ozone, one of the most reactive oxidant gases to which humans are routinely exposed, induces inflammation in the lower airways. The airway epithelium is one of the first targets that inhaled ozone will encounter, but its role in airway inflammation is not well understood. Expression of inducible genes involved in the inflammatory response, such as interleukin (IL)-8, is controlled by transcription factors. Expression of the IL-8 gene is regulated by the transcription factors nuclear factor (NF)-kappaB, NF-IL-6, and possibly activator protein-1 (AP-1). Type II-like epithelial cells (A549) were grown on a collagen-coated membrane and exposed in vitro to 0.1 ppm ozone or air. Exposure to ozone induced DNA-binding activity of NF-kappaB, NF-IL-6, and AP-1. IL-8 mRNA and IL-8 protein levels were also increased after ozone exposure. These results link ozone-induced DNA-binding activity of transcription factors and the production of IL-8 by epithelial cells thus demonstrating a potential cellular cascade resulting in the recruitment of inflammatory cells into the airway lumen.

Arsenic-induced p53-DNA binding activity in epithelial cells

2008 ◽  
pp. 489-494
Author(s):  
M Sandoval ◽  
M Morales ◽  
A Ortega ◽  
E López-Bayghen ◽  
P Ostrosky-Wegman
Keyword(s):  
Dna Binding ◽  
Epithelial Cells ◽  
Binding Activity ◽  
Dna Binding Activity

pH-Responsive DNA-Binding Activity of Helicobacter pylori NikR†

Biochemistry ◽  
2009 ◽  
Vol 48 (11) ◽  
pp. 2486-2496 ◽  
Author(s):  
Yanjie Li ◽  
Deborah B. Zamble
Keyword(s):  
Helicobacter Pylori ◽  
Dna Binding ◽  
Binding Activity ◽  
Ph Responsive ◽  
Dna Binding Activity

Crystal Structure of the TNF-α-Inducing Protein (Tipα) from Helicobacter pylori: Insights into Its DNA-Binding Activity

2009 ◽  
Vol 392 (1) ◽  
pp. 191-197 ◽  
Author(s):  
Jun Young Jang ◽  
Hye-Jin Yoon ◽  
Ji Young Yoon ◽  
Hyoun Sook Kim ◽  
Sang Jae Lee ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Helicobacter Pylori ◽  
Dna Binding ◽  
Binding Activity ◽  
Dna Binding Activity ◽  
Tnf Α

scholarly journals DNA binding activity of Helicobacter pylori DnaB helicase: the role of the N-terminal domain in modulating DNA binding activities

FEBS Journal ◽  
2011 ◽  
Vol 279 (2) ◽  
pp. 234-250 ◽  
Author(s):  
Ram G. Nitharwal ◽  
Vijay Verma ◽  
Naidu Subbarao ◽  
Santanu Dasgupta ◽  
Nirupam R. Choudhury ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Dna Binding ◽  
Binding Activity ◽  
Terminal Domain ◽  
Dna Binding Activity ◽  
Dnab Helicase
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