Prognostic factors for survival from esophageal carcinoma (ECA) in the United States: The effect of tumor size and lymph node status

2001 ◽  
Vol 120 (5) ◽  
pp. A255-A255
Author(s):  
M ELOUBEIDI ◽  
R DESMOND ◽  
C WILCOX
Keyword(s):  
United States ◽  
Prognostic Factors ◽  
Lymph Node ◽  
Esophageal Carcinoma ◽  
Tumor Size ◽  
The United States ◽  
Lymph Node Status ◽  
Node Status

Impact of Preoperative CA 15-3 Levels in Operable Breast Cancer. Comparison with Tissue Polypeptide Antigen (TPA) and Carcinoembryonic Antigen (CEA)

1991 ◽  
Vol 6 (1) ◽  
pp. 21-24 ◽  
Author(s):  
R.V. Iaffaioli ◽  
F. Caponigro ◽  
G. Esposito ◽  
C. Pagliarulo ◽  
S. Deplacido ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Lymph Node ◽  
Carcinoembryonic Antigen ◽  
Tumor Size ◽  
Operable Breast Cancer ◽  
Lymph Node Status ◽  
Tissue Polypeptide Antigen ◽  
Node Status ◽  
Similar Association

CA 15-3, TPA and CEA were assayed before surgery in 60 patients with breast cancer. A significant association was found between preoperative CA 15-3 levels and some of the most important prognostic factors in breast cancer, such as lymph node status and tumor size. No similar association was discovered for CEA and TPA. Preoperative CA 15-3 levels were also significantly associated with early recurrences of the disease, thus adding useful information to prognosis especially in N + patients.

scholarly journals The impact of primary tumor size, lymph node status, and other prognostic factors on the risk of cancer death

Cancer ◽  
2009 ◽  
Vol 115 (21) ◽  
pp. 5071-5083 ◽  
Author(s):  
L. Leon Chen ◽  
Matthew E. Nolan ◽  
Melvin J. Silverstein ◽  
Martin C. Mihm ◽  
Arthur J. Sober ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Lymph Node ◽  
Tumor Size ◽  
Primary Tumor ◽  
Lymph Node Status ◽  
Cancer Death ◽  
Primary Tumor Size ◽  
Node Status ◽  
Risk Of Cancer ◽  
The Impact

Pathologic analysis of tumor size and lymph node status in multifocal/multicentric breast carcinoma

Cancer ◽  
2002 ◽  
Vol 94 (5) ◽  
pp. 1383-1390 ◽  
Author(s):  
Aleodor A. Andea ◽  
Tracie Wallis ◽  
Lisa A. Newman ◽  
David Bouwman ◽  
Jyotirmoy Dey ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Tumor Size ◽  
Lymph Node Status ◽  
Node Status ◽  
Pathologic Analysis

Sentinel Node Status and Tumor Characteristics: A Study of 234 Invasive Breast Carcinomas

2005 ◽  
Vol 129 (1) ◽  
pp. 82-84 ◽  
Author(s):  
Ying Cao ◽  
Gladell P. Paner ◽  
Prabha B. Rajan
Keyword(s):  
Lymph Node ◽  
Tumor Size ◽  
Lymphovascular Invasion ◽  
Frozen Section ◽  
Paraffin Section ◽  
Lymph Node Status ◽  
Axillary Lymph ◽  
Breast Carcinomas ◽  
Node Status ◽  
Size Grade

Abstract Context.—Axillary lymph node status is the most important prognostic factor in patients with breast cancer. Tumor size and lymph node status, the most reliable pathologic bases of the tumor staging system, are practical parameters for estimating survival status. With the advent of lymphatic mapping and sentinel node (SN) identification, there is potential for a more efficient and sensitive evaluation of the axillary lymph node status. Objective.—To correlate SN status with tumor size, grade, and lymphovascular invasion. Design.—We examined 234 patients with unifocal breast carcinomas measuring 25 mm or less as detected by preoperative ultrasound during the period May 1998 through December 2002. Sentinel nodes were examined by frozen section and paraffin section as per protocol. Results.—Of the 234 patients, SN was identified in 221 (94.5%). An average of 1.38 SNs were examined per patient. Seventy-seven of 221 patients were SN positive on paraffin section. Sixty-six (85.7%) of these 77 cases could be correctly diagnosed as positive for metastatic carcinoma on frozen section. Two cases reported as positive on paraffin section were reported as suspicious on frozen section. Logistic regression indicated that tumor size, grade, and lymphovascular invasion were all significantly associated with SN status (P < .001). Conclusions.—Tumor size, grade, and lymphovascular invasion were significantly associated with SN status in unifocal invasive breast carcinoma.

scholarly journals Neopterin Is an Independent Prognostic Variable in Females with Breast Cancer

1999 ◽  
Vol 45 (11) ◽  
pp. 1998-2004 ◽  
Author(s):  
Christian Murr ◽  
Anton Bergant ◽  
Martin Widschwendter ◽  
Kurt Heim ◽  
Hans Schröcksnadel ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Tumor Size ◽  
Distant Metastases ◽  
Cell Immune Response ◽  
Lymph Node Status ◽  
Risk Of Death ◽  
Node Status ◽  
Urinary Neopterin

Abstract Background: Neopterin, produced by human monocytes/macrophages upon stimulation by interferon-γ, is a sensitive marker for monitoring Th1-cell immune response in humans. In malignant diseases, the frequency of increases in neopterin in the serum and urine of patients depends on tumor stage and type. Methods: In a retrospective study comprising 129 females with breast cancer, urinary neopterin/creatinine ratios were measured at the time of diagnosis. Tumor characteristics were determined concomitantly. Results: Urinary neopterin was increased in 18% of the patients. It did not correlate with tumor size or lymph node status, but it was influenced by the presence of distant metastases (P <0.05) and by tumor differentiation (P = 0.01). When product-limit estimates were calculated after follow-up for up to 13 years (median follow-up, 56 months), the presence of distant metastases (P <0.001), neopterin (P <0.001), tumor size (P = 0.001), and lymph node status (P <0.01) were significant predictors of survival. By multivariate analysis, a combination of the variables presence of distant metastases (P <0.001), neopterin (P <0.01), and lymph node status (P <0.05) was found to jointly predict survival. In lymph node-negative patients without distant metastases, the relative risk of death associated with increased neopterin concentrations was 2.5 compared with patients with neopterin concentrations within the reference interval. Conclusion: Urinary neopterin provides additional prognostic information in patients with breast cancer.

Tumor Size and Lymph Node Status in Multifocal Breast Cancer

2007 ◽  
Vol 13 (1) ◽  
pp. 68-71 ◽  
Author(s):  
Francisco Tresserra ◽  
Ignacio Rodriguez ◽  
Marta García-Yuste ◽  
Pedro J. Grases ◽  
Carmen Ara ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Tumor Size ◽  
Lymph Node Status ◽  
Node Status ◽  
Multifocal Breast Cancer

ATL

2012 ◽  
Vol 22 (7) ◽  
pp. 1226-1233 ◽  
Author(s):  
Jang Yoo ◽  
Joon Young Choi ◽  
Seung Hwan Moon ◽  
Duk Soo Bae ◽  
Soo Bin Park ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Prognostic Factors ◽  
Lymph Node ◽  
Fdg Pet ◽  
Tumor Volume ◽  
Metabolic Tumor Volume ◽  
Uterine Cervical Cancer ◽  
Lymph Node Status ◽  
Free Survival ◽  
Node Status

ObjectiveWe compared the prognostic value of volume-based metabolic parameters determined using fluorine 18 (18F) fluorodeoxyglucose (FDG) positron emission tomography (PET) (18F-FDG PET) (with other prognostic parameters in uterine cervical cancer.MethodsThe subjects were 73 female patients who had an initial diagnosis of uterine cervical cancer and who underwent 18F-FDG PET. Various metabolic or volume-based PET parameters including maximum and average standardized uptake values, metabolic tumor volume, and total lesion glycolysis (TLG) were measured in primary cervical tumors. Survival analysis for disease-free survival or progression-free survival was performed with a Kaplan-Meier method using PET parameters and other clinical variables. For determining independent prognostic factors, Cox regression analysis was performed.ResultsRecurrence or disease progression occurred in 23 patients (31.5%). In univariate analysis, patient age (cutoff, 57 years, P < 0.05), International Federation of Gynecology and Obstetrics stage (P = 0.07), primary tumor size (cutoff, 6.7 cm; P < 0.05), lymph node status on PET (P < 0.005), treatment method (P < 0.01), metabolic tumor volume (cutoff, 82 cm3; P = 0.001), and TLG (cutoff, 7600; P = 0.005) were significant predictors of recurrence or progression. In multivariate analysis, both lymph node status on PET (hazard ratio, 1.042 [negative vs intrapelvic metastasis only], 7.008 [negative vs extrapelvic metastasis]; P < 0.001) and TLG (cutoff, 7600; hazard ratio, 2.981; P < 0.05) were independent prognostic factors for predicting recurrence.ConclusionsIn uterine cervical cancer, TLG, a volume-based metabolic parameter, and lymph node status on PET may be significant independent prognostic factors for event-free survival.

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