M1189 Statin Treatment of Colon Cancer Cells Leads to an Overall Downregulation of Receptor Tyrosine Kinase Activity

Gastroenterology ◽

10.1016/s0016-5085(10)61615-0 ◽

2010 ◽

Vol 138 (5) ◽

pp. S-351

Author(s):

Rutger J. Jacobs ◽

Liudmila L. Kodach ◽

Sander H. Diks ◽

Jarom Heijmans ◽

Daniel W. Hommes ◽

...

Keyword(s):

Colon Cancer ◽

Tyrosine Kinase ◽

Cancer Cells ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Statin Treatment ◽

Colon Cancer Cells ◽

Tyrosine Kinase Activity

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Abstract B130: Monoclonal antibody (mAb)‐induced down‐regulation of the RON receptor tyrosine kinase impairs malignant phenotypes of colon cancer cells

10.1158/1535-7163.targ-09-b130 ◽

2009 ◽

Author(s):

Zhuzhu Li ◽

Sunny Guin ◽

Snehal Padhyep ◽

Hangping Yao ◽

Monghai Wang

Keyword(s):

Monoclonal Antibody ◽

Colon Cancer ◽

Tyrosine Kinase ◽

Cancer Cells ◽

Receptor Tyrosine Kinase ◽

Colon Cancer Cells ◽

Down Regulation ◽

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Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells

International Journal of Oncology ◽

10.3892/ijo_00000696 ◽

2010 ◽

Vol 37 (2) ◽

Author(s):

Wang

Keyword(s):

Monoclonal Antibody ◽

Colon Cancer ◽

Tyrosine Kinase ◽

Cancer Cells ◽

Receptor Tyrosine Kinase ◽

Colon Cancer Cells ◽

Down Regulation ◽

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The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells

Molecular Cancer ◽

10.1186/1476-4598-10-82 ◽

2011 ◽

Vol 10 (1) ◽

pp. 82 ◽

Author(s):

Hang-Ping Yao ◽

Yong-Qing Zhou ◽

Qi Ma ◽

Sunny Guin ◽

Snehal S Padhye ◽

...

Keyword(s):

Monoclonal Antibody ◽

Colon Cancer ◽

Tyrosine Kinase ◽

Tumor Growth ◽

Cancer Cells ◽

Receptor Tyrosine Kinase ◽

Colon Cancer Cells ◽

Ron Receptor ◽

Potential Therapeutics

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Overexpression of membrane glycoprotein PC-1 in MDA-MB231 breast cancer cells is associated with inhibition of insulin receptor tyrosine kinase activity.

Molecular Endocrinology ◽

10.1210/mend.10.11.8923458 ◽

1996 ◽

Vol 10 (11) ◽

pp. 1318-1326 ◽

Author(s):

A Belfiore ◽

A Costantino ◽

F Frasca ◽

G Pandini ◽

R Mineo ◽

...

Keyword(s):

Breast Cancer ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Cancer Cells ◽

Receptor Tyrosine Kinase ◽

Breast Cancer Cells ◽

Kinase Activity ◽

Membrane Glycoprotein ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase

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Prostaglandin E2Synergistically Enhances Receptor Tyrosine Kinase-dependent Signaling System in Colon Cancer Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m313276200 ◽

2004 ◽

Vol 279 (14) ◽

pp. 14287-14293 ◽

Author(s):

Jinyi Shao ◽

B. Mark Evers ◽

Hongmiao Sheng

Keyword(s):

Colon Cancer ◽

Tyrosine Kinase ◽

Cancer Cells ◽

Receptor Tyrosine Kinase ◽

Colon Cancer Cells ◽

Signaling System

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Overexpression of membrane glycoprotein PC-1 in MDA-MB231 breast cancer cells is associated with inhibition of insulin receptor tyrosine kinase activity

Molecular Endocrinology ◽

10.1210/me.10.11.1318 ◽

1996 ◽

Vol 10 (11) ◽

pp. 1318-1326 ◽

Author(s):

A. Belfiore

Keyword(s):

Breast Cancer ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Cancer Cells ◽

Receptor Tyrosine Kinase ◽

Breast Cancer Cells ◽

Kinase Activity ◽

Membrane Glycoprotein ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase

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The homeodomain transcription factor Cdx1 reduces the growth of human colon cancer cells by reducing G1 Cdk kinase activity and cyclin D1 expression

Gastroenterology ◽

10.1016/s0016-5085(01)80687-9 ◽

2001 ◽

Vol 120 (5) ◽

pp. A139-A139

Author(s):

J LYNCH ◽

M KELLER ◽

E RANSUH ◽

P TRABER

Keyword(s):

Colon Cancer ◽

Transcription Factor ◽

Cyclin D1 ◽

Cancer Cells ◽

Kinase Activity ◽

Human Colon ◽

Colon Cancer Cells ◽

Human Colon Cancer ◽

Homeodomain Transcription Factor ◽

Human Colon Cancer Cells

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Insulin receptor tyrosine kinase activity is reduced in type-2 (non-insulin-dependent) diabetes but not in obesity

Acta Endocrinologica ◽

10.1530/acta.0.114s183 ◽

1987 ◽

Vol 116 (3_Suppl) ◽

pp. S183

Author(s):

H.H. KLEIN ◽

G.R. FREIDENBERG ◽

R.R. HENRY ◽

J.M. OLEFSKY

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Insulin Dependent Diabetes ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Dependent

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Effect of streptozocin-induced diabetes on insulin-receptor tyrosine kinase activity in obese Zucker rats

Diabetes ◽

10.2337/diabetes.39.5.619 ◽

1990 ◽

Vol 39 (5) ◽

pp. 619-625 ◽

Author(s):

L. J. Slieker ◽

E. F. Roberts ◽

W. N. Shaw ◽

W. T. Johnson

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Zucker Rats ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Obese Zucker Rats

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Substitution of isoleucine for methionine at position 1153 in the beta-subunit of the human insulin receptor. A mutation that impairs receptor tyrosine kinase activity, receptor endocytosis, and insulin action.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42456-8 ◽

1992 ◽

Vol 267 (12) ◽

pp. 8383-8389 ◽

Author(s):

A Cama ◽

M.J. Quon ◽

M de la Luz Sierra ◽

S.I. Taylor

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Human Insulin ◽

Receptor Tyrosine Kinase ◽

Insulin Action ◽

Kinase Activity ◽

Beta Subunit ◽

Tyrosine Kinase Activity ◽

Receptor Endocytosis ◽

Human Insulin Receptor

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