Sa1893 Predictive Factors of Response to Intravenous Cyclosporine in Severe Ulcerative Colitis: Development of a Novel Calculation Formula for Earlier Clinical Decision-Making

2012 ◽  
Vol 142 (5) ◽  
pp. S-352
Author(s):  
Keiko Saito ◽  
Tatsuro Katsuno ◽  
Sayuri Sazuka ◽  
Masaya Saito ◽  
Yuhoko Furuya ◽  
...  
Author(s):  
Axel U. Dignass ◽  
Kristine Paridaens ◽  
Sameer Al Awadhi ◽  
Jakob Begun ◽  
Jae Hee Cheon ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. e0223893
Author(s):  
Anna Luisa Bathe ◽  
Eirini Mavropoulou ◽  
Nicolae-Catalin Mechie ◽  
Golo Petzold ◽  
Volker Ellenrieder ◽  
...  

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
C Waugh ◽  
N Jain ◽  
A Bhutta ◽  
T Havenhand ◽  
M Qureshi ◽  
...  

Abstract Introduction Covid-19 caused many service changes including limitations on operations due to potential increased mortality risk to patients. We report our findings from Trauma & Orthopaedic (T&O) surgical mortality through this period and the effectiveness of using a scoring system (The Manchester Equation) to predict likelihood of mortality. Method We reviewed all T&O admissions that underwent surgical intervention during the height of the pandemic. We recorded numerous factors for each patient including mortality and Covid status. From this we created a scoring system which is the product of Covid status, Anaesthetic type, Medical co-morbidities and other medical factors and ASA Score. We then analysed the findings to determine whether the score could be predictive of mortality rate. Results Of 123 patients undergoing surgery 6 deaths were observed (mean score of 51.3) compared to 117 patients surviving (mean score 31.9), p = 0.001. A score of less than 32 carried a 0% chance of death whereas a score of 32 or more resulted in a 14.6% mortality rate (p = 0.01). Conclusion The Manchester Equation can be used to help predict the mortality rate of T&O surgery in the presence of Covid-19 and may be useful for clinical decision making and consent purposes.


2011 ◽  
Vol 20 (4) ◽  
pp. 121-123
Author(s):  
Jeri A. Logemann

Evidence-based practice requires astute clinicians to blend our best clinical judgment with the best available external evidence and the patient's own values and expectations. Sometimes, we value one more than another during clinical decision-making, though it is never wise to do so, and sometimes other factors that we are unaware of produce unanticipated clinical outcomes. Sometimes, we feel very strongly about one clinical method or another, and hopefully that belief is founded in evidence. Some beliefs, however, are not founded in evidence. The sound use of evidence is the best way to navigate the debates within our field of practice.


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